[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616182":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":48,"locations":55,"responsibleParty":70,"collaborators":73,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":33,"eligibilityCriteria":81,"healthyVolunteers":77,"sex":82,"minAge":83,"maxAge":33,"enrollmentInfo":84,"targetDuration":33,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":57,"whyStopped":33,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Karamanoğlu Mehmetbey University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1 (home based exercise program)","ACTIVE_COMPARATOR","Group 1 will receive training on median nerve gliding exercises and self-stretching exercises for the carpal ligament. Patients will be asked to perform 3 sets of median nerve gliding exercises, each consisting of 10 repetitions, and self-stretching exercises for the carpal ligament 3 times a day for 30 seconds as part of home program.",[13],"Other: Exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"Group 2 (home based exercise program and pain neuroscience education)","EXPERIMENTAL","Group 2 will receive exercise and pain neuroscience education. The exercise will be taught as a home program, similar to the other group. Pain neuroscience training will be provided twice a week for a total of 6 sessions by a trained physical therapist.",[13,19],"Behavioral: Pain neuroscience education",[21,28],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Exercise","Stretching the transverse carpal ligament helps correct imbalance and provides more space for the median nerve, supporting nerve mobility. Stretching also balances flexor and extensor muscles, reduces tension, and supports overall hand health.\n\nNerve gliding exercises, similar to stretching, aim to restore nerve mobility and reduce symptoms.",[9,15],[26,27],"Median nerve gliding exercises","Self-stretching of carpal ligament",{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"BEHAVIORAL","Pain neuroscience education","PNE is an educational intervention aiming to alter a patient's beliefs and cognitions regarding their pain experience. The main contents addressed in the educational session were: neurophysiological aspects of pain, biopsychosocial aspects of pain, concept of peripheral and central sensitization, using audio-visual support, examples and metaphors for a better understanding by the patient, as reported in previous studies.",[15],null,[35,39,41,43,45],{"name":36,"affiliation":37,"role":38},"Mahmut Talha Susam, MD","Karamanoglu Mehmetbey University Physical Medicine and Rehabilitation","STUDY_CHAIR",{"name":36,"affiliation":37,"role":40},"PRINCIPAL_INVESTIGATOR",{"name":42,"affiliation":37,"role":40},"Aynur Başaran, Prof.MD",{"name":44,"affiliation":37,"role":40},"Süleyman Gül, PhD",{"name":46,"affiliation":47,"role":40},"Elif Dilara Durmaz, Pt","Karaman Training and Research Hospital",[49],{"name":50,"role":51,"phone":52,"phoneExt":53,"email":54},"Mahmut Talha Susam, MD.","CONTACT","5458445753","90","mahmuttalhasusam@kmu.edu.tr",[56],{"facility":47,"status":57,"city":58,"state":58,"zip":59,"country":60,"countryCode":33,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"RECRUITING","Karaman","70200","Turkey (Türkiye)",{"type":62,"coordinates":63},"Point",[64,65],33.215,37.18111,{"lat":65,"lon":64},[68],{"name":36,"role":51,"phone":69,"phoneExt":53,"email":54},"5458445752",{"type":40,"investigatorFullName":71,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":33,"oldOrganization":33},"MAHMUT TALHA SUSAM","MD",[74],{"name":47,"class":6},"100616182","the-effectiveness-of-pain-neuroscience-education-for-patients-with-carpal-tunnel-syndrome-100616182",false,"NCT07302282","The Effectiveness of Pain Neuroscience Education for Patients With Carpal Tunnel Syndrome","The Effectiveness of Pain Neuroscience Education for Patients With Mild to Moderate Carpal Tunnel Syndrome","Inclusion Criteria:\n\n* Being 18 years of age or older\n* Having a diagnosis of mild or moderate CTS confirmed by ENMG\n* Having complaints of pain and numbness in the first three fingers of the hand for at least 3 months\n\nExclusion Criteria:\n\n* Presence of severe CTS findings on electrophysiological examination\n* Presence of metabolic diseases such as uncontrolled diabetes and hypothyroidism\n* Presence of inflammatory rheumatic disease (e.g., rheumatoid arthritis)\n* Presence of other neuromuscular diseases affecting the hand and wrist (Polyneuropathy, Cervical radiculopathy, peripheral nerve damage, Brachial plexus damage, other entrapment neuropathies, etc.)\n* History of hand and wrist trauma\n* History of neck and wrist surgery\n* History of steroid injection into the carpal tunnel within the last 3 months\n* History of physical therapy application to wrist within the last 3 months\n* Deformity preventing the use of a splint on the wrist\n* Previous participation in a program for the psychological management of chronic pain\n* Cognitive dysfunction preventing cooperation with tests","ALL","18 Years",{"count":85,"type":86},48,"ESTIMATED","INTERVENTIONAL",[89],"NA","The goal of this clinical trial is to investigate the effects of Pain Neuroscience Education applied in the treatment of mild and moderate carpal tunnel syndrome (CTS).\n\nThe main question it aims to answer is: Does PNE have a therapeutic effect on carpal tunnel syndrome in clinical and ultrasonographic terms? Researchers will compare whether PNE creates a synergistic effect alongside home based exercise programs and splint application in mild to moderate CTS, and will objectively demonstrate potential benefits such as relief from pain and numbness.",[92],"Carpal Tunnel Syndrome (CTS)",[94,95,96,97,22,30,98,99],"Median Neuropathy","Mononeuropathies","Nerve Compression Syndromes","Education","Carpal tunnel syndrome","Median nerve gliding exercise","2026-01-02",{"date":102,"type":103},"2026-01-06","ACTUAL",{"date":105,"type":103},"2025-12-29",{"date":107,"type":86},"2026-08-17",{"name":5,"class":6},1]