[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601123":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":27,"responsibleParty":44,"collaborators":20,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":20,"eligibilityCriteria":52,"healthyVolunteers":49,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":20,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":30,"whyStopped":20,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"The University of Hong Kong","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"healthy adults","EXPERIMENTAL","Healthy adults aged 18-65 Self-reported food craving or weight control issues",[13],"Device: repetitive transcranial magnetic stimulation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","repetitive transcranial magnetic stimulation","Six sessions of rTMS using the EXOMIND™ device, administered once or twice a week.\n\nEach session will deliver 6,300 pulses at alternating frequencies of 12, 15, and 18 Hz, with a total duration of 24 minutes and 30 seconds.\n\nThe target site would be left dorsolateral prefrontal cortex (DLPFC), determined by the most common used 5-cm rule. The procedure would be conducted in the research centre with medical staff supported.",[9],null,[22],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Pak Wing Cheng","CONTACT","85290169487","chengpsy@hku.hk",[28],{"facility":29,"status":30,"city":31,"state":32,"zip":20,"country":31,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Sassoon Road Campus, HKU","RECRUITING","Hong Kong","Pok Fu Lam","HK",{"type":35,"coordinates":36},"Point",[37,38],114.17469,22.27832,{"lat":38,"lon":37},[41,42],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},{"name":23,"role":43,"phone":20,"phoneExt":20,"email":20},"PRINCIPAL_INVESTIGATOR",{"type":43,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Dr. Cheng Pak Wing, Calvin","Clinical Assistant Professor","100601123","the-effectiveness-of-rtms-on-improving-food-craving-and-weight-control-in-adults-without-serious-mental-illness-100601123",false,"NCT07106398","The Effectiveness of rTMS on Improving Food Craving and Weight Control in Adults Without Serious Mental Illness","Inclusion Criteria:\n\n* Healthy adults\n* Aged between 18-65\n* Self-reported food craving or weight control issues\n\nExclusion Criteria:\n\n* People with serious mental illness\n* Severe neurological conditions\n* Contraindications for rTMS\n* People on weight-reduction medications","ALL","18 Years","65 Years",{"count":57,"type":58},30,"ESTIMATED","INTERVENTIONAL",[61],"NA","Department of Psychiatry \\| Li Ka Shing Faculty of Medicine\n\nThe University of Hong Kong\n\nThe Effectiveness of rTMS on Improving Food Cravings and Weight Control\n\nin Adults without Serious Mental Illness\n\nIntroduction\n\nThe investigators would like to invite participants to participate in an observational study on the efficacy of using magnetic fields to improve food cravings and weight control in adults without serious mental illness.\n\nThe research leader is Dr. Cheng Pak Wing, Assistant Professor, Department of Psychiatry, Queen Mary Hospital\u002FHKU Li Ka Shing Faculty of Medicine.\n\nPlease read the following information carefully. If necessary, participants can discuss it with relatives, friends or doctors. If anything is unclear, or if participants would like more information, please ask us. Please carefully consider whether participants are willing to participate in this research.\n\nResearch Purpose\n\nFood cravings are a common experience that can significantly impact an individual's mental and physical health. These intense desires for specific foods often lead to overconsumption of unhealthy foods, contributing to obesity, poor nutritional intake, and associated health conditions. Understanding the neural mechanisms behind food cravings is crucial for developing effective interventions to manage them.\n\nrTMS is a non-invasive brain stimulation technique that uses magnetic fields to modulate neural activity in targeted brain regions. Over the years, rTMS has shown promise in treating various mental health conditions, including depression, obsessive-compulsive disorder (OCD) and eating disorders.\n\nResearch Methods\n\nParticipants\n\nHealthy adults aged 18-65 with self-reported food cravings or weight control issues.\n\nTreatment protocol\n\nSix sessions of rTMS using the EXOMIND™ device, administered once or twice a week.\n\nEach session will deliver 6,300 pulses at alternating frequencies of 12, 15, and 18 Hz, with a total duration of 24 minutes and 30 seconds.\n\nThe target site would be left dorsolateral prefrontal cortex (DLPFC), determined by the most common used 5-cm rule. The procedure would be conducted in the research centre with medical staff supported.\n\nA checklist of potential adverse effects from TMS administration will be referenced from existing literature to monitor tolerability and adverse events during each session. Blood pressure and heart rate will be recorded at the beginning and end of each session.\n\nAssessment\n\nParticipants will be assessed at three time points: baseline (pre-intervention), post-intervention, and four weeks post-intervention.\n\nAssessments: Food Cravings Questionnaire-Trait (FCQ-T), Perceived Stress Scale (PSS), Patient Health Questionnaire-9 (PHQ-9), and BMI.\n\nDemographics: Age, gender, years of education, place of birth, marital status, number of children, financial condition, household income, family history of eating problems will be collected upon study entry. Medical history in relation to mental illnesses and medications will also be assessed.",[64,65],"Food Cravings","rTMS",[67,68,9],"rtms","food cravings","2025-08-06",{"date":71,"type":72},"2025-08-11","ACTUAL",{"date":74,"type":72},"2025-07-04",{"date":76,"type":58},"2028-06-27",{"name":5,"class":6},1]