[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100494843":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":27,"locations":35,"responsibleParty":62,"collaborators":64,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":19,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":37,"whyStopped":19,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Rhode Island Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Low Glycemic Load Diet","EXPERIMENTAL","Feeding study with dietary composition (approximately) 50% fat, 20% protein, 30% carbohydrate.",[13],"Behavioral: Low Glycemic Load Diet",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"BEHAVIORAL","Food delivery service will provide a low glycemic load diet for 8 weeks, followed by a 4-month period of self-adherence to a low glycemic load diet with close nutritionist follow up",[9],null,[21,24],{"name":22,"affiliation":5,"role":23},"Kevin J Scully, MB BCh BAO","PRINCIPAL_INVESTIGATOR",{"name":25,"affiliation":26,"role":23},"Melissa S Putman, MD, MSc","Boston Children's Hospital",[28,32],{"name":22,"role":29,"phone":30,"phoneExt":19,"email":31},"CONTACT","401-444-5504","kevin_scully@brown.edu",{"name":25,"role":29,"phone":33,"phoneExt":19,"email":34},"617-355-7476","melissa.putman@childrens.harvard.edu",[36,51],{"facility":26,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Boston","Massachusetts","02115","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-71.05977,42.35843,{"lat":47,"lon":46},[50],{"name":25,"role":29,"phone":33,"phoneExt":19,"email":34},{"facility":5,"status":37,"city":52,"state":53,"zip":54,"country":41,"countryCode":42,"cosmosGeoPoint":55,"geoPoint":59,"contacts":60},"Providence","Rhode Island","02903",{"type":44,"coordinates":56},[57,58],-71.41283,41.82399,{"lat":58,"lon":57},[61],{"name":22,"role":29,"phone":30,"phoneExt":19,"email":31},{"type":63,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR",[65],{"name":66,"class":6},"Cystic Fibrosis Foundation","100494843","the-effects-of-a-low-glycemic-load-diet-on-dysglycemia-and-body-composition-in-adults-with-cystic-fibrosis-related-diabetes-100494843",false,"NCT05723445","The Effects of a Low Glycemic Load Diet on Dysglycemia and Body Composition in Adults With Cystic Fibrosis-Related Diabetes","DINE","Inclusion Criteria:\n\n* 18 years and above\n* Genetically confirmed diagnosis of CF\n* Diagnosis of pancreatic insufficiency, requiring pancreatic enzyme replacement\n* Criteria for CFRD:\n\nA.) Most recent OGTT 2-hour glucose \\>200 mg\u002FdL within the past two years, and\u002For; B.) HbA1c \\>6.5% in the past two years, and\u002For; C.) Current use of insulin\n\nExclusion Criteria:\n\n* FEV1 \\\u003C50% predicted on most recent pulmonary function testing\n* BMI \\\u003C18 kg\u002Fm2\n* Currently receiving enteral nutrition support via GT feeds\n* Pregnancy, plan to become pregnant in the next 3-months, or sexually active without use of contraception\n* Use of IV antibiotics or systemic supraphysiologic glucocorticoids for CF exacerbation within 1 month\n* Started or stopped treatment with a CFTR modulator within 3 months of enrollment\n* Currently adhering to an LGL or other carbohydrate-restricted diet (carbohydrate intake \\\u003C30% of total daily caloric intake)","ALL","18 Years","70 Years",{"count":78,"type":79},15,"ESTIMATED","INTERVENTIONAL",[82],"NA","This study will evalute the effect of a low glycemic load (LGL diet on dysglycemia, insulin requirements, DXA-derived body composition, gastrointestinal symptoms and quality of life measures in adults with cystic fibrosis-related diabetes (CFRD). We will use continuous glucose monitors (CGM) to assess the LGL diet both in a controlled setting (via a meal delivery company) and in free-living conditions.",[85,86,87],"Cystic Fibrosis","Cystic Fibrosis-related Diabetes","Cystic Fibrosis With Intestinal Manifestations",[89,90,91,92],"Cystic Fibrosis-Related Diabetes","Low Glycemic Load","Continuous Glucose Monitoring","Body Composition","2025-08-16",{"date":95,"type":96},"2025-08-22","ACTUAL",{"date":98,"type":96},"2023-09-01",{"date":100,"type":79},"2026-07-01",{"name":5,"class":6},2]