[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100509355":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":42,"centralContacts":46,"locations":52,"responsibleParty":71,"collaborators":24,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":24,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":24,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":24,"overallStatus":55,"whyStopped":24,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"University of New Hampshire","OTHER",[8,14,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"Low Physical Activity and Added Carbohydrate Group","EXPERIMENTAL","10-days of low physical activity (\\~5,000 steps\u002Fday) while consuming added sugar-sweetened beverages (\\~180 g\u002Fday).",[13],"Behavioral: Low Physical Activity and Added Carbohydrate Group",{"label":15,"type":16,"description":17,"interventionNames":18},"Low Physical Activity Control","PLACEBO_COMPARATOR","10-days of sedentary activity (\\~5,000 steps\u002Fday).",[19],"Behavioral: Low physical Activity Control",{"label":21,"type":22,"description":23,"interventionNames":24},"Normal Activity Control","NO_INTERVENTION","Maintains normal physical activity levels and exercise training",null,{"label":26,"type":10,"description":27,"interventionNames":28},"High Physical Activity and Added Carbohydrate Group","10-days of high physical activity (\\~11,000 steps\u002Fday) while consuming added sugar-sweetened beverages (\\~180 g\u002Fday).",[29],"Behavioral: High Physical Activity and Added Carbohydrate Group",[31,35,39],{"type":32,"name":9,"description":33,"armGroupLabels":34,"otherNames":24},"BEHAVIORAL","Young men and women will transition into a low physically active lifestyle for 10 days and consume added sugar-sweetened beverages. The intervention group will be compared to two control groups and one experimental group. One of the control groups will undergo a low physical activity intervention.",[9],{"type":32,"name":36,"description":37,"armGroupLabels":38,"otherNames":24},"Low physical Activity Control","Young men and women will transition into a low physically active lifestyle for 10 days.",[15],{"type":32,"name":26,"description":40,"armGroupLabels":41,"otherNames":24},"Young men and women will transition into a high physically active lifestyle for 10 days and consume added sugar-sweetened beverages. The intervention group will be compared to two control groups and one experimental group.",[26],[43],{"name":44,"affiliation":5,"role":45},"Michael S Brian, PhD","PRINCIPAL_INVESTIGATOR",[47],{"name":48,"role":49,"phone":50,"phoneExt":24,"email":51},"Michael Brian, PhD","CONTACT","603-714-8899","Michael.Brian@unh.edu",[53],{"facility":54,"status":55,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"University of New Hampshire Cardiometabolic Research Laboratory","RECRUITING","Durham","New Hampshire","03824","United States","US",{"type":62,"coordinates":63},"Point",[64,65],-70.92645,43.13397,{"lat":65,"lon":64},[68,70],{"name":48,"role":49,"phone":69,"phoneExt":24,"email":51},"603-862-1693",{"name":48,"role":45,"phone":24,"phoneExt":24,"email":24},{"type":45,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Michael Brian","Assistant Professor of Kinesiology","100509355","the-effects-of-an-obesogenic-lifestyle-in-recreationally-active-young-adults-100509355",false,"NCT05912348","The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults","Inclusion Criteria:\n\n* 18-30 years of age\n* Recreationally active completing 75-150 minutes of moderate-to-vigorous intensity exercise (\\>2 days\u002Fweek).\n* Fair cardiorespiratory fitness levels (Men: VO2\\>38.4 ml\u002Fkg\u002Fmin; Women: VO2\\>32.6 ml\u002Fkg\u002Fmin).\n\nExclusion Criteria:\n\n* Hypertension (resting or diagnosed)\n* Impaired fasting blood glucose (\\>100mg\u002FdL)\n* Diagnosed cardiovascular disease\n* Diagnosed diabetes\n* Diagnosed cancer\n* Diagnosed chronic kidney disease\n* Diagnosed musculoskeletal disorders that prevents the individual from exercising on a bike.",true,"ALL","18 Years","30 Years",{"count":85,"type":86},45,"ESTIMATED","INTERVENTIONAL",[89],"NA","This clinical trial aims to learn about the alterations in insulin resistance and metabolic flexibility following a transition to an obesogenic lifestyle in fit young men and women. The main questions it aims to answer are:\n\n1. Does adding excess carbohydrates when transitioning to a sedentary lifestyle promote insulin resistance and impaired 24hr glucose regulation in healthy men and women?\n2. Does adding excess carbohydrates when transitioning to a sedentary lifestyle lower the body's ability to break down fats and carbohydrates in healthy men and women?\n3. Does the added physical activity blunt shifts in carbohydrate and fat oxidation in healthy men and women?",[92,93,94,95],"Insulin Resistance","Impaired Glucose Tolerance","Obesity","Metabolic Disturbance","2024-07-16",{"date":98,"type":99},"2024-07-17","ACTUAL",{"date":101,"type":99},"2023-02-08",{"date":103,"type":86},"2026-09-30",{"name":5,"class":6},1]