[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100350609":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":27,"centralContacts":32,"locations":37,"responsibleParty":55,"collaborators":57,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":24,"eligibilityCriteria":70,"healthyVolunteers":67,"sex":71,"minAge":72,"maxAge":24,"enrollmentInfo":73,"targetDuration":24,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":24,"overallStatus":40,"whyStopped":24,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"University of Oklahoma","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"DASH Diet plus Home-Based Exercise","EXPERIMENTAL","The DASH dietary program consists of a diet emphasizing foods rich in fruits, vegetables, whole grains, and low-fat dairy, in which patients record daily servings of fruits and vegetables. The home-based exercise program consists of intermittent walking to moderate claudication pain 3 times per week for 3 months in a home-based setting.",[13],"Behavioral: DASH Diet plus Home-Based Exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"Home-Based Exercise","ACTIVE_COMPARATOR","The home-based exercise program consists of intermittent walking to moderate claudication pain 3 times per week for 3 months in a home-based setting.",[19],"Behavioral: Home-Based Exercise",[21,25],{"type":22,"name":9,"description":11,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL",[9],null,{"type":22,"name":15,"description":17,"armGroupLabels":26,"otherNames":24},[15],[28],{"name":29,"affiliation":30,"role":31},"Andrew Gardner, Ph.D.","Professor, Department of Medicine, Cardiology","PRINCIPAL_INVESTIGATOR",[33],{"name":29,"role":34,"phone":35,"phoneExt":24,"email":36},"CONTACT","405-271-4742","andrew-gardner@ouhsc.edu",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"O'Donoghue Research Building, University of Oklahoma Health Sciences Center","RECRUITING","Oklahoma City","Oklahoma","73117","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-97.51643,35.46756,{"lat":50,"lon":49},[53],{"name":54,"role":34,"phone":35,"phoneExt":24,"email":36},"Andrew W Gardner, PhD",{"type":56,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[58,60,63],{"name":59,"class":6},"Milton S. Hershey Medical Center",{"name":61,"class":62},"National Institute on Aging (NIA)","NIH",{"name":64,"class":6},"Case Western Reserve University","100350609","the-effects-of-diet-and-exercise-interventions-in-peripheral-artery-disease-100350609",false,"NCT03845036","The Effects of Diet and Exercise Interventions in Peripheral Artery Disease","Inclusion Criteria:\n\n1. History of claudication,\n2. Presence of PAD, defined by meeting at least one of the following criteria (ABI at rest \\\u003C 0.90, or \\> 20% decrease in ABI following a heel-rise exercise test in patients with a normal ABI at rest (\\> 0.90), or history of peripheral revascularization.\n\nExclusion Criteria:\n\n1. absence of PAD, defined by meeting all of the following 3 criteria (ABI at rest \\> 0.90), \\\u003C 20% decrease in ABI following a heel-rise exercise test, and no history of peripheral revascularization,\n2. non-compressible vessels (ABI \\> 1.40),\n3. rest pain due to PAD (Fontaine stage III; Rutherford Grade II),\n4. tissue loss due to PAD (Fontaine stage IV; Rutherford Grade III),\n5. use of medications indicated for the treatment of intermittent claudication (cilostazol and pentoxifylline) initiated within three months prior to investigation,\n6. peripheral revascularization within one month prior to investigation,\n7. active cancer,\n8. end stage renal disease defined as stage 5 chronic kidney disease,\n9. medical conditions that are contraindicative for exercise according to the American College of Sports Medicine,\n10. cognitive dysfunction (mini-mental state examination score \\\u003C 24), and\n11. failure to complete the baseline tests within three weeks.","ALL","40 Years",{"count":74,"type":75},150,"ESTIMATED","INTERVENTIONAL",[78],"NA","This study is a 3-month, prospective, randomized controlled clinical trial designed to address the efficacy of the DASH dietary program combined with a home-based exercise program, quantified by a step activity monitor, to improve exercise and vascular outcome measures in patients with PAD.",[81,82],"Claudication","Peripheral Artery Disease","2026-04-13",{"date":85,"type":86},"2026-04-17","ACTUAL",{"date":88,"type":86},"2024-09-16",{"date":90,"type":75},"2029-05-31",{"name":5,"class":6},1]