[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579976":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":50,"collaborators":18,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":18,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":77,"overallStatus":34,"whyStopped":18,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Ostergotland County Council, Sweden","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Diet intervention- Nordic nutrition recommendations","ACTIVE_COMPARATOR","The intervention group will receive groceries with planned recipes during the hormonal treatment period for the woman (11-14 days) before IVF. The meal plan will be according to the Nordic dietary guidelines and individualized to match total energy expenditure.",[13],"Dietary Supplement: Diet intervention NMR",{"label":15,"type":16,"description":17,"interventionNames":18},"No diet intervention","NO_INTERVENTION","No intervention - this group will only receive standard care",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DIETARY_SUPPLEMENT","Diet intervention NMR","Participants will receive groceries to their homes with planned recipes. The recipes are planned by using the Nordic nutrition councils recommendations.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Susanne Liffner, M.D, Ph.D.","CONTACT","+46 (0)101030000","susanne.liffner@liu.se",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"University Hospital","RECRUITING","Linköping","Östergötland County","58185","Sweden","SE",{"type":41,"coordinates":42},"Point",[43,44],15.62157,58.41086,{"lat":44,"lon":43},[47],{"name":48,"role":28,"phone":49,"phoneExt":18,"email":30},"Susanne Liffner, MD, PhD","+46101030000",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":54,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Susanne Liffner","Principal Investigator","Region Östergötland","100579976","the-effects-of-diet-on-small-non-coding-rna-i-sperm-cells-and-the-possible-effects-on-reproductive-success-diet-intervention-effects-on-sperm-100579976",false,"NCT06831292","The Effects of Diet on Small Non-coding RNA i Sperm Cells and the Possible Effects on Reproductive Success: Diet Intervention Effects on Sperm","Molecular Mechanisms for Male Fertility: Can Diet Change Sperm sncRNA and the Reproductive Potential?","DIET-IS","Inclusion Criteria:\n\n* Male (biological) partner in infertile couple, scheduled for first IVF treatment\n* Mature sperm cells in semen\n* Able to speak and read Swedish\n* Omnivore\n* Will refrain from nicotine and alcohol during intervention\n* Sperm sampled provided no more than 3 weeks before intervention start\n\nExclusion Criteria:\n\n* Former or present malignant disease\n* Former radiotherapy in pelvic area\n* Former chemotherapy\n* Known genetic\u002Fchromosomal disorder\n* Food allergy","MALE","23 Years","56 Years",{"count":67,"type":68},100,"ESTIMATED","INTERVENTIONAL",[71],"NA","In this study, patients with infertility treated with IVF at the Center of Reproductive Medicine in Linköping, Sweden, will receive recipes and food according to Nordic dietary guidelines. The purpose is to investigate whether a short diet intervention is sufficient to improve sperm quality and shift the small non-coding RNA profile. In our previous study sperm showed rapid response to diet.",[74,75,76],"Changes in sncRNA in Sperm","Male Fertility","RNA Profile",[78,79,80,81,82,83],"male fertility","small non-coding RNA","diet","infertility","reproduction","diet intervention","2026-05-04",{"date":86,"type":87},"2026-05-05","ACTUAL",{"date":89,"type":87},"2024-12-26",{"date":91,"type":68},"2027-12",{"name":5,"class":6},1]