[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100585677":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":40,"responsibleParty":54,"collaborators":26,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":26,"enrollmentInfo":66,"targetDuration":26,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":81,"whyStopped":26,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Swiss Paraplegic Research, Nottwil","NETWORK",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Eccentric arm-crank (KREHA) training","EXPERIMENTAL","The eccentric training intervention consists of 20 training sessions performed on a symmetric arm-crank (Krafttraining mittels exzentrischer Handkurbel, KREHA) device. The training sessions have a duration of approximately 30 min and will be completed within twelve weeks, with a maximum of three sessions per week.",[13],"Procedure: Eccentric (KREHA) training",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard clinical routine strength (STAN) training","ACTIVE_COMPARATOR","The standard strength training intervention consists of a total of 20 training sessions at the gym of the study center, performed following clinical routine procedures. The training sessions have a duration of approximately 60 min and will be completed within twelve weeks, with around three sessions per week.",[19],"Procedure: Standard clinical routine strength (STAN) training",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Eccentric (KREHA) training","20 eccentric resistance training sessions will be performed on a symmetric arm-crank ergometer in a supine position.",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"The regular strength training intervention consists of a total of 20 training sessions at the gym of the study center, performed following clinical routine procedures.",[15],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Anneke Hertig-Godeschalk, PhD","CONTACT","+414 9396603","anneke.hertig@paraplegie.ch",{"name":37,"role":33,"phone":38,"phoneExt":26,"email":39},"Fabian Ammann, MSc","+41419396624","fabian.ammann@paraplegie.ch",[41],{"facility":42,"status":26,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":26},"Swiss Paraplegic Centre","Nottwil","Canton of Lucerne","6207","Switzerland","CH",{"type":49,"coordinates":50},"Point",[51,52],8.13774,47.13469,{"lat":52,"lon":51},{"type":55,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100585677","the-effects-of-eccentric-compared-to-standard-strength-training-in-primary-spinal-cord-injury-rehabilitation-100585677",false,"NCT06905470","The Effects of Eccentric Compared to Standard Strength Training in Primary Spinal Cord Injury Rehabilitation","The Effects of Eccentric Compared to Standard Strength Training in Primary Spinal Cord Injury Rehabilitation - a Matched-Pair Randomized Controlled Trial","KREHA3","Inclusion Criteria:\n\n* 18 years or older.\n* informed consent as confirmed per signature.\n* traumatic or disease-related SCI.\n* participating in the routine strength training program during primary SCI rehabilitation at the study center (generally this is initiated around one month after SCI onset).\n* wheelchair dependency during activities of daily living, defined by a score of 0-2 in the SCIM subsection regarding \"Mobility in the house\".\n* passed sports medical assessment and having sufficient biceps\u002Ftriceps function to perform arm-crank training, as determined by an experienced sports medicine physician\n\nExclusion Criteria:\n\n* inflammatory or neurodegenerative diseases (including multiple sclerosis or Guillain-Barré syndrome).\n* comorbidities or other health issues that may interfere with study participation, inability or contraindications to undergo the investigated intervention.\n* MRI contraindications (magnetic metal parts or electronic implants such as pacemakers in the body).\n* pregnancy (anamnestic).","ALL","18 Years",{"count":67,"type":68},20,"ESTIMATED","INTERVENTIONAL",[71],"NA","The goal of this clinical trial is to assess the effects of eccentric arm-crank (KREHA) training compared to standard clinical routine strength (STAN) training in individuals undergoing primary spinal cord injury (SCI) rehabilitation.\n\nThe main questions this trail aims to answer are:\n\n* what are the effects of the training on upper body strength, aerobic performance, muscle volume, functional independence, and health-related quality of life?\n* is the KREHA training feasible to implement into the rehabilitation routine?\n\nParticipants will:\n\n* perform either 20 KREHA sessions or 20 STAN sessions within 12 weeks\n* perform a test battery to collect data on training effects before (pretest) and after (posttest) the study intervention",[74],"Spinal Cord Injury",[76,77,78,79,80],"eccentric training","strength training","upper body","aerobic performance","muscle volume","NOT_YET_RECRUITING","2025-12-01",{"date":84,"type":85},"2025-12-02","ACTUAL",{"date":87,"type":68},"2026-03-01",{"date":89,"type":68},"2028-03-01",{"name":5,"class":6},1]