[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100500762":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":38,"centralContacts":42,"locations":47,"responsibleParty":66,"collaborators":30,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":30,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":30,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":89,"overallStatus":49,"whyStopped":30,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"National Yang Ming Chiao Tung University","OTHER",[8,15,21],{"label":9,"type":10,"description":11,"interventionNames":12},"Neurofeedback combined with MI (NFB-MI)","EXPERIMENTAL","Participants in both NFB-MI and MI groups will receive a total of 12 sessions of training in 4 weeks. NFB-MI group will receive fNIRS-based neurofeedback during MI training in lab. Prior to each NFB-MI session, participants will watch a video of a person executing balance tasks and walking in different environments. The explicit instruction will be given by the researcher. Each MI training session (consisting of 5 trials for balance and walking tasks) includes 45 seconds of imagery tasks followed by 15 seconds of rest, repeated twice. The training will take approximately 20 minutes. Visual feedback with a thermometer based on the changes of HbO concentration will be displayed on the screen during NFB-MI training.\n\nIn each training session, actual balance and gait tasks will be practiced for 20 min. The difficulty of the tasks will be modified individually for each participant.",[13,14],"Other: fNIRS-based neurofeedback with motor imagery","Other: Motor training",{"label":16,"type":17,"description":18,"interventionNames":19},"Motor imagery","ACTIVE_COMPARATOR","Participants in both NFB-MI and MI groups will receive a total of 12 sessions of training in 4 weeks. MI group will practice kinesthetic MI under supervision in lab setting. Participants will watch a video of a person executing balance tasks and walking in different environments before MI training. The explicit instruction will be given by the researcher. Each MI training session (consisting of 5 trials for balance and walking tasks) includes 45 seconds of imagery tasks followed by 15 seconds of rest, repeated twice. The training will take approximately 20 minutes.\n\nIn each training session, actual balance and gait tasks will be practiced for 20 min after MI training. The difficulty of the tasks will be modified individually for each participant. The researcher will ensure the safety of executing each task during lab visit.",[20,14],"Other: Kinesthetic motor imagery",{"label":22,"type":17,"description":23,"interventionNames":24},"Motor training","The tasks for balance and gait training are similar to those during the MI training. The balance and gait training will be practiced for 20 min in MI and NFB-MI groups, and will be practiced for 40 min in MT group. The difficulty of the tasks will be modified individually for each participant. The researcher will ensure the safety.",[14],[26,31,35],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"fNIRS-based neurofeedback with motor imagery","A multichannel wearable fNIRS (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) will be used to detect the cortical activity in SMA. The HbO concentration will be processed and displayed as a visual feedback during MI training.",[9],null,{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Kinesthetic motor imagery","Prior to each task, participants will watch a video of a person executing balance tasks and walking tasks. The balance tasks will include static and dynamic standing tasks such as sit-to-stand, tandem stance, standing on a balance board, reaching out to different directions and single leg stance. The walking tasks consists of tandem walking, crossing obstacles, sideward walking, backward walking, and turning. The participants will be asked to kinesthetically imagine movements in the first-person perspective, and the researcher will give the explicit instruction encouraging them to focus on the feeling (i.e. tactile, proprioceptive and kinesthetic sensations). Each MI session consists of 10-min of balance tasks and 10-min of walking tasks.",[16],{"type":6,"name":22,"description":36,"armGroupLabels":37,"otherNames":30},"The tasks for balance and gait training are similar to those during the MI training. The difficulty of the tasks will be modified individually for each participant. The researcher will ensure the safety.",[16,22,9],[39],{"name":40,"affiliation":5,"role":41},"Ray-Yau Wang","PRINCIPAL_INVESTIGATOR",[43],{"name":40,"role":44,"phone":45,"phoneExt":30,"email":46},"CONTACT","+88628267210","rywang@nycu.edu.tw",[48],{"facility":5,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"RECRUITING","Taipei","None Selected","112","Taiwan","TW",{"type":56,"coordinates":57},"Point",[58,59],121.52639,25.05306,{"lat":59,"lon":58},[62,65],{"name":63,"role":44,"phone":64,"phoneExt":30,"email":46},"Ray-Yau Wang, Ph.D","88628267210",{"name":63,"role":41,"phone":30,"phoneExt":30,"email":30},{"type":41,"investigatorFullName":40,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Professor","100500762","the-effects-of-fnirs-based-neurofeedback-training-on-balance-and-gait-in-parkinsons-disease-100500762",false,"NCT05800470","The Effects of fNIRS-based Neurofeedback Training on Balance and Gait in Parkinson's Disease","The Novel Application of fNIRS-based Neurofeedback to Enhance Effects of Motor Imagery on Balance and Gait Performance in Individuals With Parkinson's Disease","Part 1\n\nAdditional Inclusion Criteria for PD:\n\n1. diagnosis of idiopathic PD by neurologist with Hoehn and Yahr stage \\\u003C 4;\n2. stable medical condition;\n3. capability of walking independently without walking devices.\n\nExclusion Criteria:\n\n1. cognitive impairment indicated by MMSE score \\\u003C 24;\n2. motor imagery ability indicated by KVIQ score \\\u003C 25;\n3. unable recognize 26 letters in the English alphabet\n4. history of diseases or conditions known to interfere with participating this study (e.g. epilepsy, metal implants in the brain, or deep brain stimulation);\n5. diagnosis of any other neurological disease or psychiatric disorder (e.g. stroke, anxiety disorder, or depression);\n6. using central nervous system medications other than for PD, e.g. antiepileptic drugs in recent 3 months.\n\nPart 2\n\nInclusion Criteria:\n\n1. aged 40-85 y\u002Fo;\n2. diagnosis of idiopathic PD by neurologist with Hoehn and Yahr stage \\\u003C 4;\n3. stable medical condition;\n4. capability of walking independently for 10 minutes, which is the time needed for imagery walking training in order to eliminate the possible influence of physical fatigue.\n\nExclusion Criteria:\n\n1. cognitive impairment indicated by MMSE score \\\u003C 24;\n2. history of diseases or conditions known to interfere with participating this study (e.g. epilepsy, metal implants in the brain, or deep brain stimulation);\n3. diagnosis of any other neurological disease or psychiatric disorder (e.g. stroke, anxiety disorder, or depression);\n4. using central nervous system medications other than for PD, e.g. antiepileptic drugs in recent 3 months.",true,"ALL","40 Years","85 Years",{"count":80,"type":81},93,"ESTIMATED","INTERVENTIONAL",[84],"NA","A cross-sectional study (part 1) aims to investigate the influence of fatigue on the MI ability in PD compared to healthy controls. A randomized controlled trial (part 2) aims to compare the effect of fNIRS-based NFB-MI on balance and gait performance versus MI only in people with PD.",[87,88],"Parkinson Disease","Movement Disorder, Functional",[90,16,91],"Neurofeedback","Parkinson's disease","2025-08-03",{"date":94,"type":95},"2025-08-07","ACTUAL",{"date":97,"type":95},"2025-03-19",{"date":99,"type":81},"2025-08-01",{"name":5,"class":6},1]