[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638614":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":54,"collaborators":26,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":26,"enrollmentInfo":66,"targetDuration":26,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":80,"overallStatus":82,"whyStopped":26,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Hacettepe University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MICT Group (Moderate-Intensity Continuous Training)","ACTIVE_COMPARATOR","Cycle ergometer-based MICT, twice weekly for 8 weeks, starting at 60% of peak workload, progressing to 80%. Sessions include 5-min warm-up, 20-30 min exercise, 5-min cool-down, followed by 30-min individualized physiotherapy.",[13],"Behavioral: Moderate-Intensity Continuous Training (MICT)",{"label":15,"type":16,"description":17,"interventionNames":18},"HIIT Group (High-Intensity Interval Training)","EXPERIMENTAL","HIIT on cycle ergometer, twice weekly for 8 weeks. Protocol: 5-min warm-up (40% peak workload), 10 × 1-min intervals at 90% peak workload with 1-min active recovery (60% peak workload) between each, followed by 5-min cool-down. Total session: \\~20 min aerobic + 30-min individualized physiotherapy.",[19],"Behavioral: High-Intensity Interval Training (HIIT)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Moderate-Intensity Continuous Training (MICT)","Cycle ergometer-based exercise, twice weekly for 8 weeks. Starting intensity at 60% of peak workload, progressing to 80%. Each session includes 5-min warm-up, 20-30 min continuous exercise, and 5-min cool-down, followed by 30-min individualized physiotherapy program.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"High-Intensity Interval Training (HIIT)","Cycle ergometer-based exercise, twice weekly for 8 weeks. Each session includes 5-min warm-up (40% peak workload), 10 × 1-min intervals at 90% peak workload with 1-min active recovery (60% peak workload) between each interval, and 5-min cool-down. Total aerobic exercise duration: \\~20 min, followed by 30-min individualized physiotherapy program.",[15],[32],{"name":33,"affiliation":5,"role":34},"Yeliz SALCI","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Kübra Turan, Msc, PT","CONTACT","+90 506 516 41 58","kubraaturann5@gmail.com",[42],{"facility":5,"status":26,"city":43,"state":26,"zip":26,"country":44,"countryCode":26,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Ankara","Turkey (Türkiye)",{"type":46,"coordinates":47},"Point",[48,49],32.85427,39.91987,{"lat":49,"lon":48},[52],{"name":53,"role":38,"phone":39,"phoneExt":26,"email":40},"Kübra Turan",{"type":34,"investigatorFullName":53,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PhD Candidate \u002F Physiotherapist","100638614","the-effects-of-high-intensity-interval-training-on-gait-balance-and-cognitive-functions-in-individuals-with-multiple-sclerosis-100638614",false,"NCT07578740","The Effects of High-Intensity Interval Training on Gait, Balance, and Cognitive Functions in Individuals With Multiple Sclerosis","Investigating the Effects of High-Intensity Interval Training on Gait, Balance, and Cognition in Individuals With Multiple Sclerosis","HIIT-MS","Inclusion Criteria:\n\n* Diagnosed with Multiple Sclerosis by a neurologist (Hacettepe University Hospitals, Neurology Outpatient Clinic)\n* Age 18 years and older\n* EDSS score between 0 and 4\n* Score of 24 or above on the Standardized Mini Mental State Examination\n* No relapse in the past 3 months\n* Medically stable for at least 6 months\n\nExclusion Criteria:\n\n• Any additional cardiopulmonary, neurological, or systemic disease other than MS","ALL","18 Years",{"count":67,"type":68},40,"ESTIMATED","INTERVENTIONAL",[71],"NA","This study aims to comparatively investigate the effects of low-volume High-Intensity Interval Training (HIIT) versus Moderate-Intensity Continuous Training (MICT) on gait, balance, cognitive functions, and neurovascular biomarkers (BDNF, VEGF) in individuals with Multiple Sclerosis (MS). This randomized controlled trial will be conducted at Hacettepe University, Faculty of Physical Therapy and Rehabilitation.",[74,75,76,77,78,79],"Multiple Sclerosis","High-intensity Interval Training","Gait","Balance","Cognition","Biomarkers",[81],"Multiple Sclerosis, High-Intensity Interval Training, HIIT, Gait, Balance, Cognition, BDNF, VEGF, Randomized Controlled Trial","NOT_YET_RECRUITING","2026-05-18",{"date":85,"type":86},"2026-05-20","ACTUAL",{"date":88,"type":68},"2026-07",{"date":90,"type":68},"2028-06",{"name":5,"class":6},1]