[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622301":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":42,"responsibleParty":67,"collaborators":23,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":23,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":23,"enrollmentInfo":78,"targetDuration":23,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":91,"overallStatus":95,"whyStopped":23,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Hacettepe University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Manual therapy Group","EXPERIMENTAL","Muscle energy techniques and diaphragmatic relaxation techniques",[13],"Other: Manual therapy Group",{"label":15,"type":6,"description":16,"interventionNames":17},"Control Group","Respiratory exercises and stretching exercises Stretching will be applied to the following muscle groups: pectoralis major and minor, upper trapezius, scalene muscles, sternocleidomastoid, and latissimus dorsi.",[18],"Other: Control group",[20,24],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":23},"For muscle energy techniques, the post-isometric relaxation (PIR) technique will be applied. Participants will be instructed to perform an isometric contraction against mild resistance (20-30% of maximal effort), which will be maintained for 7-10 seconds, followed by a 3-second relaxation period. PIR applications will be performed bilaterally for each muscle group, in 2 sets with a total of 10 repetitions. The muscle groups to which MET will be applied include the pectoralis major and minor, upper trapezius, scalene muscles, sternocleidomastoid, and latissimus dorsi. For the diaphragmatic relaxation technique, the therapist will follow the elevation of the ribs and gently draw the contact points cranially and slightly laterally. During expiration, the therapist will maintain resistance by deepening the contact toward the internal costal margin. The maneuver will be applied in two sets of 10 deep breaths, with a 1-minute rest interval between sets.",[9],null,{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":23},"Control group","Self-stretching and breathing exercise",[15],[29],{"name":30,"affiliation":5,"role":31},"Aynur Demirel","STUDY_CHAIR",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":23,"email":37},"Aynur Demirel, PT, PhD, Assoc. Prof.","CONTACT","+903051576168","aynur.demirel@hacettepe.edu.tr",{"name":39,"role":35,"phone":40,"phoneExt":23,"email":41},"Hidaye Yamikan, PT, MSc.","+905349898724","hidaye.yamikan@hacettepe.edu.tr",[43],{"facility":5,"status":23,"city":44,"state":45,"zip":46,"country":47,"countryCode":23,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Ankara","Samanpazari","06100","Turkey (Türkiye)",{"type":49,"coordinates":50},"Point",[51,52],32.85427,39.91987,{"lat":52,"lon":51},[55,56,57,59,61,63,65],{"name":34,"role":35,"phone":36,"phoneExt":23,"email":37},{"name":39,"role":35,"phone":23,"phoneExt":23,"email":41},{"name":39,"role":58,"phone":23,"phoneExt":23,"email":23},"SUB_INVESTIGATOR",{"name":34,"role":60,"phone":23,"phoneExt":23,"email":23},"PRINCIPAL_INVESTIGATOR",{"name":62,"role":58,"phone":23,"phoneExt":23,"email":23},"Semra Topuz, PT, PhD, Prof.",{"name":64,"role":58,"phone":23,"phoneExt":23,"email":23},"Ali Yalcin, PT, PhD.",{"name":66,"role":58,"phone":23,"phoneExt":23,"email":23},"Oguz Karcioglu, MD, Assoc. Prof.",{"type":60,"investigatorFullName":30,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"PT, PhD, Assoc. Prof.","100622301","the-effects-of-manual-therapy-on-the-spatiotemporal-gait-characteristics-in-patients-with-chronic-obstructive-pulmonary-disease-100622301",false,"NCT07381842","The Effects of Manual Therapy on the Spatiotemporal Gait Characteristics in Patients With Chronic Obstructive Pulmonary Disease","An Investigation of the Effects of Manual Therapy on the Spatiotemporal Gait Characteristics in Patients With Chronic Obstructive Pulmonary Disease","Inclusion Criteria:\n\n* Age 40 years or older\n* Clinically stable for at least the past 4 weeks\n* Classified as GOLD stage 1, 2, or 3 according to the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) airflow limitation classification\n* Classified as group A, B, or E according to the GOLD ABE assessment tool\n\nExclusion Criteria:\n\n* Use of walking assistive devices\n* Receiving long-term oxygen therapy\n* Presence of additional orthopedic, neuromuscular, neurological, or cardiac conditions that may affect gait and balance\n* History of lung cancer, sarcoidosis, tuberculosis, and\u002For lung surgery\n* Presence of musculoskeletal conditions such as fibromyalgia, rheumatoid arthritis, or osteoarthritis\n* Presence of a known mental or cognitive impairment","ALL","40 Years",{"count":79,"type":80},40,"ESTIMATED","INTERVENTIONAL",[83],"NA","The primary aim of this study is to investigate the effects of manual therapy on spatiotemporal characteristics of gait and gait variability, functional exercise capacity, and pulmonary function in patients with chronic obstructive pulmonary disease (COPD).\n\nThe secondary aims of the study are to determine the effects of manual therapy on balance, respiratory muscle strength, quality of life, physical activity, symptom severity, accessory respiratory muscle activation, peripheral muscle strength, chest wall mobility, dysfunctional breathing, pain, and posture.",[86,87,88,89,90],"COPD (Chronic Obstructive Pulmonary Disease)","Manuel Therapy","Gait Biomechanics","Muscle Energy Technique","Functional Capacity",[92,93,94],"COPD","Gait","Manuel therapy","NOT_YET_RECRUITING","2026-01-26",{"date":98,"type":99},"2026-02-02","ACTUAL",{"date":101,"type":80},"2026-02-08",{"date":103,"type":80},"2028-01-08",{"name":5,"class":6},1]