[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633111":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":24,"locations":30,"responsibleParty":44,"collaborators":18,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":18,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":55,"minAge":56,"maxAge":18,"enrollmentInfo":57,"targetDuration":18,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":67,"overallStatus":69,"whyStopped":18,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"University of Auckland, New Zealand","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Open label placebo","EXPERIMENTAL","Participants in this arm are assigned to receive a placebo nasal spray. This arm allows testing of the effects on an open-label placebo compared to a control condition. Participants in this arm will self-administer the nasal spray once in each nostril before entering through the gate to jump.",[13],"Other: Open Label Placebo",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","Participants in this arm receive no treatment and will continue as normal. This group serves as a no intervention comparator to assess the effects of the open label placebo.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Open Label Placebo","Participants allocated to the placebo arm will self-administer the nasal spray before entering through the gate to jump. The nasal spray contains no active ingredients. It is made of a saline solution and is described to participants as a placebo. Participants are informed that placebos can produce powerful effects and have been shown to reduce stress and anxiety through expectations and prior learning - processes where the body learns to respond automatically to cues that are associated with a relief in symptoms.",[9],[25],{"name":26,"role":27,"phone":28,"phoneExt":18,"email":29},"Keith J Petrie, PhD","CONTACT","6493737599","kj.petrie@auckland.ac.nz",[31],{"facility":32,"status":18,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":18},"Canyon Swing","Queenstown","Otago","9300","New Zealand","NZ",{"type":39,"coordinates":40},"Point",[41,42],168.66271,-45.03023,{"lat":42,"lon":41},{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Keith J Petrie","Professor","100633111","the-effects-of-open-label-placebos-on-acute-stress-100633111",false,"NCT07522437","The Effects of Open-label Placebos on Acute Stress","Inclusion Criteria:\n\n* Signed-up to complete the canyon swing\n* Aged 18 years and over\n* Able to speak and understand English\n* Comfortable being randomised to either the open-label placebo or no-treatment control condition\n\nExclusion Criteria:\n\n* Under 18 years of age\n* Unable to speak or understand English\n* Unable to provide informed consent",true,"ALL","18 Years",{"count":58,"type":59},260,"ESTIMATED","INTERVENTIONAL",[62],"NA","The goal of this study is to find out whether an open-label placebo nasal spray can reduce stress among individuals engaging in a high-stress canyon swing. The main questions the study aims to answer are: 1) Does an open-label placebo increase likelihood of participants completing another jump? 2) Does the placebo affect how long it takes participants to jump, reduce the reported stress levels before the jump 3) Does the placebo change how enjoyable participants find the jump?\n\nResearchers will compare participants who receive an open-label placebo nasal spray (a spray that contains no active medication and is clearly described as a placebo) with participants who receive no treatment (control). The aim is to see whether the placebo nasal spray can increase likelihood of participants completing another jump, reduce reported stress and improve participants overall enjoyment of the jump.\n\nParticipants will:\n\n* Complete a short questionnaire before they jump\n* Either self administer a placebo nasal spray (one spray in each nostril) right before stepping through the gate to jump, or receive no treatment (control).\n* Complete a short questionnaire after completing the jump\n* Whether they complete another jump will be noted",[65,66],"Acute Stress","Stress",[9,68,32],"Acute stress","NOT_YET_RECRUITING","2026-04-09",{"date":72,"type":73},"2026-04-13","ACTUAL",{"date":75,"type":59},"2026-04",{"date":77,"type":59},"2026-11",{"name":5,"class":6},1]