[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100475706":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":28,"responsibleParty":45,"collaborators":49,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":10,"eligibilityCriteria":60,"healthyVolunteers":57,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":10,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"University of Iowa","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Cystic Fibrosis Carrier Group",null,"Participants who have been identified as Cystic Fibrosis Carriers via previous genetic testing.",{"label":13,"type":10,"description":14,"interventionNames":10},"Control Group","Participants who have been identified as not being Cystic Fibrosis Carriers via previous genetic testing.",[16],{"name":17,"affiliation":5,"role":18},"Philip M Polgreen, MD","PRINCIPAL_INVESTIGATOR",[20,24],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","(319) 384-6194","philip-polgreen@uiowa.edu",{"name":25,"role":21,"phone":26,"phoneExt":10,"email":27},"Shelby L Francis, PhD","319-678-8037","shelby-francis@uiowa.edu",[29],{"facility":30,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"University of Iowa Hospitals and Clinics","RECRUITING","Iowa City","Iowa","52242","United States","US",{"type":38,"coordinates":39},"Point",[40,41],-91.53017,41.66113,{"lat":41,"lon":40},[44],{"name":25,"role":21,"phone":26,"phoneExt":10,"email":27},{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Philip Polgreen","Professor, Internal Medicine",[50,53],{"name":51,"class":52},"National Institutes of Health (NIH)","NIH",{"name":54,"class":52},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","100475706","the-effects-of-the-cf-carrier-state-on-the-kidneys-and-pancreas-100475706",false,"NCT05474417","The Effects of the CF Carrier State on the Kidneys and Pancreas","CF Carrier Inclusion Criteria:\n\n* A CF Carrier identified via genetic testing\n\nControl Inclusion Criteria:\n\n* No previous CF carrier test results\n\nExclusion Criteria:\n\n* CF patient status\n* Unable to speak English\n* Currently pregnant\n* Unable to provide written informed consent\n* Prisoner status\n* Currently taking any medications for the treatment of diabetes","ALL","18 Years","100 Years",{"count":65,"type":66},1250,"ESTIMATED","OBSERVATIONAL","The overarching hypothesis is that CF carriers are at increased risk for developing most of the extrapulmonary conditions associated with CF compared to the general population. Specifically, it is hypothesized that this pilot data will detect subclinical evidence of pancreatic and kidney disorders among CF carriers. This will be determined by bringing CF carriers and controls to the CRU for one visit where they will answer survey questions and undergo laboratory testing. Additionally, they will collect urine and stool samples at home that will be sent to outside laboratories for testing.",[70,71,72],"Carrier State","Pancreatic Disease","Kidney Diseases","2026-01-05",{"date":75,"type":76},"2026-01-07","ACTUAL",{"date":78,"type":76},"2021-12-20",{"date":80,"type":66},"2026-07",{"name":47,"class":6},1]