[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594782":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":40,"responsibleParty":59,"collaborators":26,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":26,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":26,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":26,"overallStatus":82,"whyStopped":26,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Guang'anmen Hospital of China Academy of Chinese Medical Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"elecrtoacupuncture group (EA group)","EXPERIMENTAL","Participants will be treated by electroacupuncture. During the first week (from day -3 to +4 of menstruation), they will receive 1-2 sessions, followed by 2-3 sessions per week for the next three weeks. This treatment schedule will be repeated for three consecutive menstrual cycles, totaling a 12-week treatment period and 30 sessions. All treatment sessions will be monitored and recorded using a treatment diary.",[13],"Device: electroacupuncture",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham elecrtoacupuncture group (sham EA group)","SHAM_COMPARATOR","Participants will be treated by sham electroacupuncture. The treatment frequency and sessions will be the same as in EA group, and the treatment diary will also be used in SEA group.",[19],"Device: Sham electroacupuncture",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","electroacupuncture","The supine position, the local skin of the acupoints was routinely sterilized, and the selected acupoints were pasted with Acupuncture auxiliary device. The main acupuncture points are DU20, bilateral EX-HN5, ST8, GB20, GB20, LI4, LR3, ST40. Select compatible acupoints based on the patient's accompanying symptoms: 1.Discomfort in the neck: EX-B2 of Cervical 3-4; 2.Emotional anxiety, depression or sleep disorders: GV29, HT7; 3.Stomach or abdominal discomfort: CV12, ST25 and CV6. The disposable acupuncture needles and the electronic acupuncture treatment instrument SDZ-V nerve and muscle intimulator both manufactured by Suzhou Medical Appliance Factory Co., Ltd., China.The specifications of acupuncture needles are Φ0.30×25mm, Φ0.30×40mm. The needles will be inserted into the skin of acupuncture points and manipulated manually by using the techniques such as lifting, thrusting, and twirling, until the internal compound sensation known as deqi.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham electroacupuncture","The SEA group will use Hua Tuo brand disposable blunt-tip sham needles (Φ0.3mm×25mm) and the electronic acupuncture treatment instrument SDZ-V nerve and muscle intimulator both manufactured by Suzhou Medical Appliance Factory Co., Ltd., China. Sham points 1-2, 3-4, 5-6, and 7-8 are bilaterally located at the midpoints between the following pairs of acupoints: SP19 and EX-UE12, SP6 and LR5, EX-UE1 and HT1, and HT7 and SI8. sham LI4: Bilateral of midpoint between acupoint LI4 and LU9; sham LR3: Bilateral of midpoint between acupoint LR3 and ST44; sham ST40: Bilateral of midpoint between acupoint ST40 and GB35. Compatible acupoints: EX-B2 of Cervical 3-4 horizontal side by 0.5 cun; sham GV29: midpoint between acupoint GV29 and BL2. sham CV12: midpoint between acupoint CV12 and ST21; sham ST25: Bilateral of midpoint between acupoint ST25 and SP15; sham CV6: 3 cun lateral to the level of the CV6; The width of the interphalangeal joint of the patient's thumb was 1 \"cun\".",[15],[32],{"name":33,"affiliation":5,"role":34},"Weiming Wang, Ph.D","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","+8613426424993","wangweiming1a1@163.com",[41],{"facility":42,"status":26,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Department of Acupuncture, China Academy of Chinese Medical Sciences Guang'anmen Hospital","Beijing","Beijing Municipality","100053","China","CN",{"type":49,"coordinates":50},"Point",[51,52],116.39723,39.9075,{"lat":52,"lon":51},[55],{"name":56,"role":37,"phone":57,"phoneExt":26,"email":58},"Xinkun Liu","+8613876859860","liuxinkunleo@qq.com",{"type":34,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"weiming wang","Principal Investigator","100594782","the-efficacy-and-safety-of-acupuncture-for-prophylaxis-of-menstrually-related-migraine-100594782",false,"NCT07023926","The Efficacy and Safety of Acupuncture for Prophylaxis of Menstrually Related Migraine","The Efficacy and Safety of Acupuncture for Prophylaxis of Menstrually Related Migraine: a Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n1. meet the diagnostic criteria for MRM according to the ICHD-3, with a documented history of MRM for at least 12 months;\n2. have a confirmed diagnosis of migraine by a neurologist;\n3. aged 18-45 years;\n4. have regular menstrual cycles (28 ± 7 days) with menstruation lasting 3-7 days;\n5. have experienced ≥3 headache days during each menstrual cycle (days -2 to +3) and ≥5 total headache days per cycle over the past 3 months and baseline period; migraine attacks must last 4-72 hours without acute medication, or at least 2 hours when treated;\n6. have completed a headache diary during the screening period (covering at least one full menstrual cycle), demonstrating good compliance;\n7. headache diary data during screening period must meet the ICHD-3 criteria for MRM and fulfill criteria (4) and (5);\n8. voluntarily sign the informed consent.\n\nExclusion Criteria:\n\n1. irregular menstrual cycles, defined as cycle length outside the range of 28±7 days or menstruation duration \\\u003C3 days or \\>7 days;\n2. presence of secondary headache disorders, facial neuralgia, or cranial neuralgia;\n3. combined with serious primary diseases such as cardiovascular, hepatic, renal, gastrointestinal, or hematological disorders that may interfere with the treatment protocol, or comorbid neurological conditions such as epilepsy, parkinson's disease, or other central nervous system disorders;\n4. headache symptoms caused by other conditions, such as moderate to severe head or neck trauma, perimenstrual infections, intracranial tumors, intracranial infections, endocrine or metabolic disorders;\n5. receipt of preventive treatment for headache within 1 month prior to the screening visit;\n6. afraid of needles or received acupuncture treatment within 3 months;\n7. unwillingness to undergo the study intervention or failure to sign the informed consent.","FEMALE","18 Years","45 Years",{"count":73,"type":74},40,"ESTIMATED","INTERVENTIONAL",[77],"NA","Acupuncture is commonly used for the prevention of migraine and tension-type headaches, and has been found to be effective in reducing both the frequency and severity of these conditions. However, studies on acupuncture for menstrually related migraine (MRM) are limited, and current research has not been able to determine whether its efficacy is due to the actual therapeutic effects of acupuncture or psychological benefits. To address this issue, the investigators have designed a clinical trial to evaluate the efficacy of acupuncture for MRM.",[80,81],"Menstrually Related Migraine","Electroacupuncture","NOT_YET_RECRUITING","2025-06-14",{"date":85,"type":86},"2025-06-17","ACTUAL",{"date":88,"type":74},"2025-07-01",{"date":90,"type":74},"2027-01-31",{"name":5,"class":6},1]