[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100518971":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":36,"centralContacts":40,"locations":50,"responsibleParty":69,"collaborators":72,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":10,"eligibilityCriteria":81,"healthyVolunteers":77,"sex":82,"minAge":10,"maxAge":83,"enrollmentInfo":84,"targetDuration":10,"studyType":87,"phases":10,"briefSummary":88,"conditions":89,"keywords":10,"overallStatus":53,"whyStopped":10,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Beijing Children's Hospital","OTHER",[8,14,18,22,26],{"label":9,"type":10,"description":11,"interventionNames":12},"growth hormone deficiency(GHD)",null,"Growth hormone deficiency (GHD) is a rare and treatable condition that causes short height in children and metabolic issues in adults.",[13],"Drug: Polyethylene glycol recombinant human growth hormone injection",{"label":15,"type":10,"description":16,"interventionNames":17},"Idiopathic short stature (ISS)","Idiopathic short stature is a condition in which the height of the individual is more than 2 SD below the corresponding mean height for a given age, sex and population, in whom no identifiable disorder is present.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"small for gestational age (SGA)","Small for gestational age (SGA) is defined as a birth weight of less than 10th percentile for gestational age.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Turner Syndrome (TS)","Turner syndrome, a condition that affects only females, results when one of the X chromosomes (sex chromosomes) is missing or partially missing.",[13],{"label":27,"type":10,"description":28,"interventionNames":29},"others","others who with the height of the individual is more than 2 SD below the corresponding mean height for a given age, sex and population.",[13],[31],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":10},"DRUG","Polyethylene glycol recombinant human growth hormone injection","0.1-0.3mg\u002Fkg.w",[15,23,9,27,19],[37],{"name":38,"affiliation":5,"role":39},"Bingyan Cao, Dr.","PRINCIPAL_INVESTIGATOR",[41,46],{"name":42,"role":43,"phone":44,"phoneExt":10,"email":45},"Chunxiu Gong, Dr.","CONTACT","13370115001","chunxiugong@163.com",{"name":47,"role":43,"phone":48,"phoneExt":10,"email":49},"Jiajia Chen, Dr.","13810773718","chenjiaj2009@126.com",[51],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Department of Endocrinology, Genetics, Metabolism","RECRUITING","Beijing","Beijing Municipality","010","China","CN",{"type":60,"coordinates":61},"Point",[62,63],116.39723,39.9075,{"lat":63,"lon":62},[66],{"name":67,"role":43,"phone":44,"phoneExt":68,"email":45},"chunxiu Gong, doctor","59616326",{"type":39,"investigatorFullName":70,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Chunxiu Gong","Principal Investigator",[73],{"name":74,"class":6},"University of Glasgow","100518971","the-efficacy-and-safety-of-pegylated-gh-for-the-treatment-of-short-stature-in-chinese-children-globe-reg-100518971",false,"NCT06037473","The Efficacy and Safety of PEGylated GH for the Treatment of Short Stature in Chinese Children-GLOBE Reg","A Real-world Study of the Efficacy and Safety of PEGylated Recombinant Human Growth Hormone Injection in the Treatment of Short Stature in Chinese Children From the Global Registry for Novel Therapies For Rare Bone or Endocrine Conditions","Inclusion Criteria:\n\nPatients with endogenous growth hormone deficiency, Turner Syndrome, SGA, idiopathic short stature, etc. treated with polyethylene glycol recombinant human growth hormone injection\n\nExclusion Criteria:\n\nPatients with serious heart and lung, blood system, malignant tumors and other diseases or systemic infections, immune function is low and Persons with mental illness;","ALL","18 Years",{"count":85,"type":86},2600,"ESTIMATED","OBSERVATIONAL","In order to further observe the long-term safety and effectiveness of real-world polyethylene glycol-recombinant human growth hormone(PEG-rhGH) treatment of GHD, idiopathic short stature, and SGA in children, explore and analyze the factors affecting the efficacy of PEG-rhGH and the height prediction model after treatment, etc., collect and analyze more scientifically and rationally, and understand the situation of real-world PEG-GH treatment. A database registration study was developed.",[90,91],"Growth Hormone Treatment","Growth Disorders","2025-08-28",{"date":94,"type":95},"2025-09-04","ACTUAL",{"date":97,"type":95},"2023-08-01",{"date":99,"type":86},"2029-08-01",{"name":5,"class":6},1]