[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100541038":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":52,"collaborators":26,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":26,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":26,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Necmi Kadıoğlu Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Crystallized phenol","ACTIVE_COMPARATOR","Crystallized phenol group: The patients will undergo to crystallized phenol application.",[13],"Procedure: crystallized phenol",{"label":15,"type":16,"description":17,"interventionNames":18},"Crystallized phenol + platelet rich plasma","EXPERIMENTAL","Crystallized phenol + platelet rich plasma group. Alongside the crystallized phenol application + patients also will receive platelet rich plasma injections in the same session.",[19],"Procedure: crystallized phenol + platelet rich plasma application",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","crystallized phenol + platelet rich plasma application","At our pilonidal care clinic, patients will undergo a comprehensive treatment regimen starting with manual or laser hair removal to reduce hair by over 90%. For pilonidal abscesses, we will perform incision, drainage, and antibiotic therapy. Treatments will include local anesthesia with lidocaine and epinephrine, thorough disinfection with povidone-iodine, and wound irrigation. Sinuses will be treated by removing hair and curettage, followed by protective ointment application and crystallized phenol to fill the cavity, ensuring precise dosing and safety.\n\nFor enhanced healing, crystallized phenol + platelet-rich plasma application patients will receive platelet-rich plasma injections to minimize infection risk and promote tissue regeneration, all under strict sterilization to maintain cleanliness and efficacy.",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"crystallized phenol","At our pilonidal care clinic, patients will undergo a comprehensive treatment regimen starting with manual or laser hair removal to reduce hair by over 90%. For pilonidal abscesses, we will perform incision, drainage, and antibiotic therapy. Treatments will include local anesthesia with lidocaine and epinephrine, thorough disinfection with povidone-iodine, and wound irrigation. Sinuses will be treated by removing hair and curettage, followed by protective ointment application and crystallized phenol to fill the cavity, ensuring precise dosing and safety.",[9],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Mustafa Azizoğlu, MD, PhD","CONTACT","+905447448244","mdmazizoglu@gmail.com",[38],{"facility":39,"status":40,"city":41,"state":26,"zip":42,"country":43,"countryCode":26,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Mustafa Azizoğlu","RECRUITING","Istanbul","34430","Turkey (Türkiye)",{"type":45,"coordinates":46},"Point",[47,48],28.94966,41.01384,{"lat":48,"lon":47},[51],{"name":39,"role":34,"phone":35,"phoneExt":26,"email":36},{"type":53,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100541038","the-efficacy-of-combining-platelet-rich-plasma-with-crystallized-phenol-in-pilonidal-sinus-disease-100541038",false,"NCT06324656","The Efficacy of Combining Platelet-rich Plasma With Crystallized Phenol in Pilonidal Sinus Disease","The Efficacy of Combining Platelet-rich Plasma With Crystallized Phenol in Pilonidal Sinus Disease Treatment in Children: A Double-blind Single-center Randomized Controlled Trial","Inclusion Criteria:\n\nThe study will be included patients with pilonidal sinus disease aged between 0 to 18 years.\n\nExclusion Criteria:\n\nPatients who had undergone prior pilonidal sinus disease surgery or had anomalies in the sacrococcygeal region will be excluded from the study. Additionally, patients who will decline to participate in the study or will be failed to attend post-procedural outpatient follow-ups will also be excluded.","ALL","1 Day","18 Years",{"count":65,"type":66},100,"ESTIMATED","INTERVENTIONAL",[69],"NA","The use of local liquid phenol for pilonidal sinus disease was first introduced by Maurica and Greenwood in 1964. Phenol, also known as carbolic acid, has been proven to be an effective sclerosing agent for treating pilonidal sinus diseas. Its antiseptic and anesthetic qualities make it suitable for application in awake patients under local anesthesia. The treatment of pilonidal sinus diseas in children with crystallized phenol was first published by Ateş et al in 2018. However, the treatment involving only crystallized phenol can require numerous sessions, potentially extending the duration of the treatment. IIn this study, the investigators, investigated whether the application of platelet-rich plasma following crystallized phenol treatment could accelerate the healing process and reach better outcomes. This study evaluates the efficacy of PRP as a treatment modality for pilonidal sinus disease in pediatric patients.",[72],"Pilonidal Sinus",[74,75,76],"pilonidal sinus","Children","platelet rich plasma","2024-08-19",{"date":79,"type":80},"2024-08-20","ACTUAL",{"date":82,"type":80},"2023-11-21",{"date":84,"type":66},"2024-09-30",{"name":5,"class":6},1]