[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624103":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":25,"responsibleParty":41,"collaborators":25,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":25,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":25,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":65,"whyStopped":25,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":25},{"fullName":5,"class":6},"Second Affiliated Hospital, School of Medicine, Zhejiang University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"hyperbaric oxygen group","EXPERIMENTAL","The treatment is administered at an atmospheric pressure of 2 ATA, with 100% oxygen inhalation.",[13],"Other: hyperbaric oxygen therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"non hyperbaric oxygen group","SHAM_COMPARATOR","The treatment is administered at an atmospheric pressure of 1.4 ATA with an inhaled oxygen fraction of 21%",[19],"Other: non Hyperbaric Oxygen Therapy",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"hyperbaric oxygen therapy","The treatment is administered at an atmospheric pressure of 2 ATA, with 100% oxygen inhalation. Oxygen inhalation time: 40 minutes (inhaling oxygen for 20 minutes, resting for 5 minutes, inhaling oxygen for 20 minutes, decompression), once daily, for 14 consecutive days. (Commenced immediately after randomisation)",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"non Hyperbaric Oxygen Therapy","The treatment is administered at an atmospheric pressure of 1.4 ATA with an inhaled oxygen fraction of 21%, oxygen inhalation time: 40 minutes (20 minutes of oxygen inhalation, 5 minutes rest, 20 minutes of oxygen inhalation, decompression), once daily, for 14 consecutive days. (Commences immediately after randomisation)",[15],[31],{"name":32,"affiliation":33,"role":34},"Bing Xiong","2nd Affiliated Hospital, School of Medicine, Zhejiang University, China","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},"Bing Xiong, MD","CONTACT","86-13516803156","2202030@zju.edu.cn",{"type":42,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100624103","the-efficacy-of-hyperbaric-oxygen-on-acute-ankle-sprain-100624103",false,"NCT07405281","the Efficacy of Hyperbaric Oxygen on Acute Ankle Sprain","A Multicenter, Prospective Clinical Randomized Controlled Study of the Efficacy of Hyperbaric Oxygen on Acute Ankle Sprain","Inclusion Criteria:\n\n* Unilateral ankle sprain;\n* Swelling, bruising, and pain at the site of the sprain;\n* Injury occurring within 72 hours;\n* MRI examination clearly shows ligament damage.\n\nExclusion Criteria:\n\n* X-ray shows ankle fracture;\n* Ankle has skin lesions or skin diseases;\n* History of lower limb and pelvic surgery;\n* Obvious neurological or psychiatric disorders that may interfere with assessment;\n* Severe ligament injuries or joint instability requiring surgical treatment;\n* Previous ankle injuries, persistent pain or functional limitations;\n* Pneumothorax, severe emphysema, active bleeding, or other diseases with contraindications for hyperbaric oxygen therapy.","ALL","18 Years","60 Years",{"count":54,"type":55},208,"ESTIMATED","INTERVENTIONAL",[58],"NA","Investigators recruited 208 patients with acute ankle sprain who were from the Rehabilitation Department of the Second Affiliated Hospital of Zhejiang University, School of Medicine from January 2026 to November 2028. Perform the improvement in AOFAS scores and Baird-Jackson ankle scores study and Rehabilitation assessments followed up after 3 years.",[61],"Ankle Sprain",[63,64],"acute ankle sprain","hyperbaric oxygen","NOT_YET_RECRUITING","2026-02-11",{"date":68,"type":69},"2026-02-12","ACTUAL",{"date":71,"type":55},"2026-03",{"date":73,"type":55},"2029-03",{"name":5,"class":6}]