[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618480":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":33,"locations":39,"responsibleParty":53,"collaborators":57,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":32,"enrollmentInfo":69,"targetDuration":32,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":81,"overallStatus":85,"whyStopped":32,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Ministry of Health, Kuwait","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Non-invasive brain stimulation","EXPERIMENTAL","Sinusoidal current used between two electrodes on the dorsolateral prefrontal cortex (DLPFC) area. - Gamma-Transcranial Alternating Current Stimulation (tACS) of 2 mA at 40 Hz will be given to the experimental group. - Session duration will last 20 minutes, of 5 session\u002Fweek, for 3weeks.",[13],"Device: Non-invasive brain stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham Non-invasive brain stimulation","SHAM_COMPARATOR","Sinusoidal current used between two electrodes on the dorsolateral prefrontal cortex (DLPFC) area. - To maintain this stimulation's indistinguishability from the experimental stimulation, the control group will be given an electric current that ramps down 60 seconds after the stimulation begins. - Session duration will last 20 minutes, of 5 session\u002Fweek, for 3weeks.",[19],"Device: Sham Non-Invasive brain stimulation",[21,27],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Non-invasive brain stimulation (NIBS) modifies brain activity without surgery using electric currents. - Transcranial alternating current stimulation (tACS) is one type of NIBS that modifies neuronal oscillations in the brain by applying alternating electrical currents to the scalp through electrodes. - This method can enhance motor abilities, improve cognitive functions, and be used in rehabilitation. - It does this by entraining neurones, which synchronise their firing to the applied sinusoidal frequency. Gamma-Transcranial Alternating Current Stimulation (tACS) of 2 mA at 40 Hz will be given to the experimental group.",[9],[26],"NIBS",{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Sham Non-Invasive brain stimulation","Non-invasive brain stimulation (NIBS) modifies brain activity without surgery using electric currents. - Transcranial alternating current stimulation (tACS) is one type of NIBS that modifies neuronal oscillations in the brain by applying alternating electrical currents to the scalp through electrodes. - This method can enhance motor abilities, improve cognitive functions, and be used in rehabilitation. - It does this by entraining neurones, which synchronise their firing to the applied sinusoidal frequency. The electric current used as ramps down 60 seconds after the stimulation begins.",[15],[26],null,[34],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},"Shahad Alkandari, Master's degree","CONTACT","+96597533309","alkandari-shahad@hotmail.com",[40],{"facility":41,"status":32,"city":42,"state":32,"zip":32,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Imam Abdulrahman Bin Faisal University","Dammam","Saudi Arabia","SA",{"type":46,"coordinates":47},"Point",[48,49],50.10326,26.43442,{"lat":49,"lon":48},[52],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"SPONSOR_INVESTIGATOR","Shahad Abdulrahman Alkandari","Shahad Alkandari MSc, PT.",[58],{"name":41,"class":59},"OTHER","100618480","the-efficacy-of-non-invasive-brain-stimulation-on-cognitive-functions-in-patients-with-chronic-obstructive-pulmonary-disease-double-blinded-randomised-controlled-trial-100618480",false,"NCT07332169","The Efficacy of Non-invasive Brain Stimulation on Cognitive Functions in Patients With Chronic Obstructive Pulmonary Disease: Double-Blinded Randomised Controlled Trial","NIBS COPD","Inclusion Criteria:\n\n* Adult age from eighteen years old and above.\n* Patients with confirmed COPD via pulmonary function test (PFT) according to the classifications of GOLD.\n* All stages of GOLD will be included\n* Stable patients, which means they were not admitted to the hospital in the last 3 months\n* Patients with COPD with confirmed cognitive impairment by MoCA test.\n* All MoCA stages will be included.\n\nExclusion Criteria:\n\n* Patients without COPD\n* Unstable patients with several admission in the last 3 months\n* Patients with COPD but without cognitive impairment.\n* COPD patients who suffered from any neurological problems\n* COPD patients who are contraindicated for using brain stimulation like psychiatric disorders.","ALL","18 Years",{"count":70,"type":71},24,"ESTIMATED","INTERVENTIONAL",[74],"NA","The goal of this clinical trial is to examine if non-invasive brain stimulation (NIBS) can enhance cognitive function with chronic obstructive pulmonary disease (COPD) population. The main questions it aims to answer are:\n\n* What is the possibility effect of using the NIBS on cognitive functions as well as the cardiopulmonary parameters in COPD population?\n* What is the relation between cognitive function parameters and cardiopulmonary parameters in COPD population who suffer from cognitive impairment (CI)? Researchers will compare NIBS to a sham-NIBS to see if NIBS works to improve cognitive function in COPD population.\n\nParticipants will:\n\nReceive NIBS or a sham-NIBS 5 sessions\u002Fweek for 3 weeks for 20 min each session.\n\nVisit the clinic at the beginning for baseline assessment then after the completion of the 3 weeks to reassess them.\n\nOutcome measures for cognitive parameters and pulmonary parameters will be taken pre and post NIBS intervention",[77,78,79,80],"COPD","COPD (Chronic Obstructive Pulmonary Disease)","Cognitive Impairment (CI)","Non-invasive Brain Stimulation",[77,26,82,83,84],"non-invasive brain stimulation","cognitive function","cognitive impairment","NOT_YET_RECRUITING","2025-12-28",{"date":88,"type":89},"2026-01-12","ACTUAL",{"date":91,"type":71},"2026-01-20",{"date":93,"type":71},"2028-11-30",{"name":55,"class":6},1]