[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100522563":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":33,"locations":42,"responsibleParty":60,"collaborators":11,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":11,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":11,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":11,"overallStatus":83,"whyStopped":11,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"The University of Texas Health Science Center, Houston","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"KARL STORZ Curved Scope","EXPERIMENTAL",null,[13],"Device: Curved KARL STORZ fetoscope",{"label":15,"type":16,"description":11,"interventionNames":17},"Conventional scopes","ACTIVE_COMPARATOR",[18],"Device: Conventional Scopes",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DEVICE","Curved KARL STORZ fetoscope","The KARLZ STORZ curved scope is used to see the inside of a pregnant person's uterus during minimally invasive surgery, similar to conventional scopes. The curved scope is rounded and thought to help visualize the anterior placenta because of its position on the uterus.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Conventional Scopes","The conventional scopes are regularly used during laser photocoagulation of placental anastomoses.",[15],[30],{"name":31,"affiliation":5,"role":32},"Jimmy Espinoza, MD, MSc,FACOG","PRINCIPAL_INVESTIGATOR",[34,38],{"name":31,"role":35,"phone":36,"phoneExt":11,"email":37},"CONTACT","(713) 500-5859","Jimmy.Espinoza@uth.tmc.edu",{"name":39,"role":35,"phone":40,"phoneExt":11,"email":41},"Elisa Garcia","713-500-6347","Elisa.I.Garcia@uth.tmc.edu",[43],{"facility":44,"status":11,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"The University of Texas Health Science Center at Houston","Houston","Texas","77030","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-95.36327,29.76328,{"lat":54,"lon":53},[57,59],{"name":58,"role":35,"phone":36,"phoneExt":11,"email":37},"Jimmy Espinoza, MD,MSc,FACOG",{"name":39,"role":35,"phone":40,"phoneExt":11,"email":41},{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"SPONSOR_INVESTIGATOR","Jimmy Espinoza","Professor","100522563","the-efficacy-of-the-karl-storz-curved-fetoscope-and-straight-fetoscope-for-laser-photocoagulation-of-placental-anastomoses-100522563",false,"NCT06084247","The Efficacy of the KARL STORZ Curved Fetoscope and Straight Fetoscope for Laser Photocoagulation of Placental Anastomoses","An Open Label Randomized-control Study on the Efficacy of the KARL STORZ Curved Fetoscope (11508aak) and Its Straight Version (11506aak) for Laser Photocoagulation of Placental Anastomoses","Inclusion Criteria:\n\n* pregnancy\n* The patient fulfills the criteria for laser photocoagulation of placental anastomoses based on the standard of care\n* fetal diagnosis of twin-to-twin transfusion syndrome\n* Anterior placenta\n* The patient provides signed informed consent that details the maternal and fetal risks involved with the procedure\n\nExclusion Criteria:\n\n* Contraindication to abdominal surgery, fetoscopic surgery, or general anesthesia\n* Allergy or previous adverse reaction to a study medication specified in this protocol\n* The patient does not fulfill the conventional criteria to undergo in-utero surgery, which is specific for each surgery\n* Preterm labor, preeclampsia, or a uterine anomaly (e.g., large fibroid tumor) that is unavoidable during surgery in the index pregnancy\n* Fetal aneuploidy, genomic variants of known significance if an amniocentesis has been performed, other major fetal anomalies or disorders that may impact the fetal\u002Fneonatal survival, or a known syndromic mutation\n* Suspicion of a major recognized syndrome by ultrasound or MRI\n* Maternal BMI \\>40 kg\u002Fm2\n* High risk for fetal hemophilia","FEMALE","18 Years","45 Years",{"count":75,"type":76},160,"ESTIMATED","INTERVENTIONAL",[79],"NA","The purpose of this study is to evaluate the efficacy of KARL STORZ curved fetoscope (11508AAK) and its straight version (11506AAK) for laser photocoagulation of placental anastomoses in patients with an anterior placenta and Twin to Twin Transfusion Syndrome (TTTS).",[82],"Twin to Twin Transfusion Syndrome","NOT_YET_RECRUITING","2025-08-11",{"date":86,"type":87},"2025-08-14","ACTUAL",{"date":89,"type":76},"2025-09-01",{"date":91,"type":76},"2027-12-01",{"name":62,"class":6},1]