[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100486822":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":25,"responsibleParty":42,"collaborators":46,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":62,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":70,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Chinese PLA General Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Medical treatment group",null,"Conservative medical treatment",{"label":13,"type":10,"description":14,"interventionNames":10},"Surgical treatment group","Direct revascularization, indirect revascularization or combined revascularization",[16],{"name":17,"affiliation":5,"role":18},"Lou Xin, MD, PhD","STUDY_CHAIR",[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Jinhao Lyu","CONTACT","+8615903562929","330322990@qq.com",[26],{"facility":5,"status":27,"city":28,"state":29,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"RECRUITING","Beijing","Beijing Municipality","100853","China","CN",{"type":34,"coordinates":35},"Point",[36,37],116.39723,39.9075,{"lat":37,"lon":36},[40],{"name":41,"role":22,"phone":10,"phoneExt":10,"email":24},"Jinhao Lyu, MD",{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Xin Lou","Chairman",[47],{"name":48,"class":6},"Beijing Tiantan Hospital","100486822","the-evolution-and-prognosis-of-moyamoya-disease-100486822",false,"NCT05619068","The Evolution and Prognosis of Moyamoya Disease","Imaging Investigation on the Evolution and Prognosis of Moyamoya Disease","Inclusion Criteria:\n\n* Patients with MMD: Conventional angiography or MRI examination conforms to the Guidelines for Diagnosis and Treatment of MMD (Neurol Med Chir (Tokyo) 52, 245-266, 2012), It is characterized by stenosis or occlusion of the end of the internal carotid artery, anterior cerebral artery and\u002For the beginning of the middle cerebral artery of unknown cause, accompanied by dilatation of the perforating artery at the base of the brain or of capillaries on the surface of the brain, i.e., the formation of smoke vessels. Sign the informed consent. Older than 10 and younger than 60. The education level of patients reached primary school or above (years of education ≥6).\n\nExclusion Criteria:\n\n* Patients with massive cerebral infarction, multiple paraventricular ischemic foci, or significantly enlarged ventricular hydrocephalus after intracerebral hemorrhage. Patients with vascular diseases caused by immune system disease. Patients can not cooperate to complete the cognitive function test. There are other neuropsychiatric diseases that affect cognitive function (such as Alzheimer's disease, Parkinson's disease, depression, anxiety disorder, cerebral hemorrhage, hydrocephalus, craniocerebral trauma, etc.). Patients with contraindications of magnetic resonance examination (patients with pacemakers, nerve stimulators, artificial metal heart valves and other metal foreign bodies) or unable to complete image collection.","ALL","10 Years","60 Years",{"count":60,"type":61},300,"ESTIMATED","5 Years","OBSERVATIONAL","To investigate the evolution of imaging appearances and cognitive function of Moyamoya disease (MMD) and to establish a prognosis evaluation system based on imaging biomarkers in MMD. The study may be helpful to optimize and improve the diagnosis and pretreatment assessment of MMD, and provide an important theoretical supplement to the existing guidelines for the management of MMD.",[66,67,68,69],"Moyamoya Disease","Revascularization","Cognitive Impairment","Functional Impairment",[71,67,72,73],"Moyamoya disease","Cognitive impairment","Functional impairment","2022-12-19",{"date":76,"type":77},"2022-12-21","ACTUAL",{"date":79,"type":77},"2022-09-01",{"date":81,"type":61},"2027-12-31",{"name":5,"class":6},1]