[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100551076":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":37,"locations":44,"responsibleParty":85,"collaborators":25,"id":87,"slug":88,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":91,"acronym":25,"eligibilityCriteria":92,"healthyVolunteers":93,"sex":94,"minAge":95,"maxAge":25,"enrollmentInfo":96,"targetDuration":25,"studyType":99,"phases":100,"briefSummary":102,"conditions":103,"keywords":111,"overallStatus":47,"whyStopped":25,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":127},{"fullName":5,"class":6},"Unity Health Toronto","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Genetics Navigator","EXPERIMENTAL","Participants in the intervention arm will use the Genetics Navigator to support the delivery of genetic services, including intake, education, pre- and post-test counselling, return of results, and physician-generated management recommendations. Participants in the experimental arm will also receive standard of care genetics care.",[13],"Behavioral: Genetics Navigator",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Care with Genetics Professionals","ACTIVE_COMPARATOR","Participants in the control arm will receive their genetic counselling and test results through usual care, which consists of in-person\u002Fphone\u002Fvideo-conference consults with genetic counsellors and medical geneticists.",[19],"Behavioral: Standard Care with Genetics Professionals",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","The Genetics Navigator will be used to support patients during the delivery of genetic services, including intake, education, pre- and post-test counselling, and physician-generated management recommendations",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Standard care for the delivery of genetic services, including receiving genetic counselling and test results",[15],[30,34],{"name":31,"affiliation":32,"role":33},"Yvonne Bombard, PhD","St. Michael's Hospital and University of Toronto","PRINCIPAL_INVESTIGATOR",{"name":35,"affiliation":36,"role":33},"Robin Hayeems, PhD","The Hospital for Sick Children and University of Toronto",[38],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},"Marc Clausen, MA","CONTACT","416-864-6060","77397","Marc.Clausen@unityhealth.to",[45,63,76],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Mount Sinai Hospital","RECRUITING","Toronto","Ontario","M5G 1X5","Canada","CA",{"type":54,"coordinates":55},"Point",[56,57],-79.39864,43.70643,{"lat":57,"lon":56},[60,61],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},{"name":62,"role":33,"phone":25,"phoneExt":25,"email":25},"Melyssa Aronson, MS (C)CGC",{"facility":64,"status":47,"city":48,"state":49,"zip":65,"country":51,"countryCode":52,"cosmosGeoPoint":66,"geoPoint":68,"contacts":69},"The Hospital for Sick Children","M5G 1X8",{"type":54,"coordinates":67},[56,57],{"lat":57,"lon":56},[70,75],{"name":71,"role":40,"phone":72,"phoneExt":73,"email":74},"Stephanie Luca, MA","416-813-7654","328163","stephanie.luca@sickkids.ca",{"name":35,"role":33,"phone":25,"phoneExt":25,"email":25},{"facility":77,"status":47,"city":48,"state":25,"zip":25,"country":51,"countryCode":52,"cosmosGeoPoint":78,"geoPoint":80,"contacts":81},"Sunnybrook Hospital",{"type":54,"coordinates":79},[56,57],{"lat":57,"lon":56},[82,83],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},{"name":84,"role":33,"phone":25,"phoneExt":25,"email":25},"Andrea Eisen, MD",{"type":86,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100551076","the-genetics-navigator-evaluating-a-digital-platform-for-genomics-health-services-100551076",false,"NCT06455384","The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services","Inclusion:\n\n* Adult patients (18 years of age or older) who are referred to participating clinicians at Mount Sinai Hospital for clinical genetic testing.\n* Parents\u002Flegal guardians (18 years of age or older) of pediatric patients who are referred to participating clinicians at SickKids for clinical genetic testing.\n\nExclusion:\n\n* Known not to be eligible for clinical genetic testing in Ontario\n* Requires urgent clinical genetic testing or prenatal genetic testing\n* Not fluent in English (speaking and reading)",true,"ALL","18 Years",{"count":97,"type":98},170,"ESTIMATED","INTERVENTIONAL",[101],"NA","Genetic testing (GT) (including targeted panels, exome and genome sequencing) is increasingly being used for patient care as it improves diagnosis and health outcomes. In spite of these benefits, genetic testing is a complex and costly health service. This results in unequal access, increased wait times and inconsistencies in care. The use of e-health tools to support genetic testing delivery can result in a better patient experience and reduced distress associated with waiting for results and empower patients to receive and act on medical results. We have previously developed and tested an interactive, adaptable and patient-centred digital decision support tool (Genetics ADvISER) to be used for genetic testing decision making, and have now developed the Genetics Navigator (GN), a patient-centred e-health navigation platform for end-to-end genetic service delivery. The objective of this study is to evaluate the effectiveness of the GN in an RCT in reducing distress with patients and parents of patients being offered genetic testing. Results of this trial will be used to establish whether the GN is effective to use in practice. If effective, GN could fill a critical clinical care gap and improve health outcomes and service use by reducing counselling burden as well as overuse, underuse and misuse of services. These are concerns policy makers seek to address through the triple aims of health care1. This study represents a significant advance in personalized health by assessing the effectiveness of this novel, comprehensive e-health platform to ultimately improve genetic service delivery, accessibility, patient experiences, and patient outcomes.",[104,105,106,107,108,109,110],"Cardiac Conditions","Connective Tissue Diseases","Retinal Disease","Epilepsy in Children","Neurodevelopmental Disorders","Cancer","Polyposis",[112,113,114,115,116,117],"Genomic Sequencing","Randomized Controlled Trial","Clinical Utility","Personal Utility","Decision Aid","Incidental Findings","2026-06-19",{"date":120,"type":121},"2026-06-24","ACTUAL",{"date":123,"type":121},"2025-10-28",{"date":125,"type":98},"2027-07",{"name":5,"class":6},3]