[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100309092":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":17,"centralContacts":21,"locations":27,"responsibleParty":41,"collaborators":43,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":73,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Wageningen University","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Persons with Lynch syndrome",null,[12],"Other: No intervention, observational study.",[14],{"type":6,"name":15,"description":10,"armGroupLabels":16,"otherNames":10},"No intervention, observational study.",[9],[18],{"name":19,"affiliation":5,"role":20},"Ellen Kampman, PhD","PRINCIPAL_INVESTIGATOR",[22],{"name":23,"role":24,"phone":25,"phoneExt":10,"email":26},"Fränzel van Duijnhoven, PhD","CONTACT","+31 317 485 375","franzel.vanduijnhoven@wur.nl",[28],{"facility":5,"status":29,"city":30,"state":10,"zip":10,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"RECRUITING","Wageningen","Netherlands","NL",{"type":34,"coordinates":35},"Point",[36,37],5.66667,51.97,{"lat":37,"lon":36},[40],{"name":23,"role":24,"phone":25,"phoneExt":10,"email":26},{"type":42,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[44,46,48],{"name":45,"class":6},"Wereld Kanker Onderzoek Fonds",{"name":47,"class":6},"Dutch Cancer Society",{"name":49,"class":50},"Funding: Biobanking and BioMolecular resources Research Infrastructure The Netherlands","UNKNOWN","100309092","the-geolynch-cohort-study-100309092",false,"NCT03303833","The GEOLynch Cohort Study","The GEOLynch Cohort Study: Genetic, Environmental and Other Factors That Influence Tumour Risk Among Persons With Lynch Syndrome","GEOLynch","Inclusion Criteria:\n\n* Persons with a known mutation in a gene that causes Lynch syndrome, i.e. with an inherited monoallelic pathogenic germline mutation in either the MLH1, MSH2, MSH6, PMS2 or EPCAM gene.\n* Aged between 18 and 80 years at inclusion.\n\nExclusion Criteria:\n\n* Additional carrier of another hereditary colon cancer predisposition syndrome (e.g. FAP)\n* (Chronic) Inflammatory bowel disease\n* Non-Dutch speaking\n* Dementia or another mental condition that makes it impossible to fill out questionnaires\n* Terminally ill persons",true,"ALL","18 Years","80 Years",{"count":64,"type":65},1000,"ESTIMATED","OBSERVATIONAL","The GEOLynch cohort study has been established to investigate the influence of genetic, environmental and other factors on tumour risk in persons with Lynch syndrome.",[69,70,71,72],"Lynch Syndrome","Neoplasms","Hereditary Nonpolyposis Colorectal Cancer","Colorectal Neoplasms",[74,75],"Lifestyle","Nutrition","2017-10-05",{"date":78,"type":79},"2017-10-06","ACTUAL",{"date":81,"type":79},"2006-07-01",{"date":83,"type":65},"2030-12",{"name":5,"class":6},1]