[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552240":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":62,"collaborators":65,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":26,"eligibilityCriteria":79,"healthyVolunteers":75,"sex":80,"minAge":81,"maxAge":26,"enrollmentInfo":82,"targetDuration":26,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":26,"overallStatus":39,"whyStopped":26,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Sir Run Run Shaw Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"treatment arm","ACTIVE_COMPARATOR","The frequency of the stimulation was 77.5Hz and the intensity was 15mA. Each participant was treated twice a day for 40 minutes each time, with an interval of more than 3 hours between the two sessions for 30 days",[13],"Device: high-frequency transcranial alternating current stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"sham-treatment arm","SHAM_COMPARATOR","The frequency of the stimulation was 77.5Hz and the intensity was 0mA. Each participant was treated twice a day for 40 minutes each time, with an interval of more than 3 hours between the two sessions for 30 days",[19],"Device: sham high-frequency transcranial alternating current stimulation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","high-frequency transcranial alternating current stimulation","The experimental group received real stimulation of high-frequency transcranial alternating current stimulation (Hi-tACS).The treatment duration is 30 days, with two sessions per day, each lasting 40 minutes.The experimental group received Hi-tACS with parameters set at 77.5Hz and 15mA.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"sham high-frequency transcranial alternating current stimulation","The the control group received sham stimulation of high-frequency transcranial alternating current stimulation (Hi-tACS).The treatment duration is 30 days, with two sessions per day, each lasting 40 minutes.The experimental group received Hi-tACS with parameters set at 0mA",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Jinsong Tang, Doctorate","CONTACT","+8613627311963","tangjinsong@zju.edu.cn",[38,49],{"facility":5,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":26,"geoPoint":26,"contacts":45},"RECRUITING","Hanzhou","Zhejiang","310020","China","CN",[46],{"name":47,"role":34,"phone":48,"phoneExt":26,"email":36},"Jinsong Tang","13627311963",{"facility":50,"status":39,"city":51,"state":41,"zip":52,"country":43,"countryCode":44,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Quzhou Third Hospital","Quzhou","324003",{"type":54,"coordinates":55},"Point",[56,57],118.86861,28.95944,{"lat":57,"lon":56},[60],{"name":61,"role":34,"phone":26,"phoneExt":26,"email":26},"Xiaofeng Gao",{"type":63,"investigatorFullName":47,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Deputy chief physician",[66,69,71],{"name":67,"class":68},"Quzhou Third hospital","UNKNOWN",{"name":70,"class":6},"Taizhou Second People's Hospital",{"name":72,"class":68},"the Seventh Hospital of Shaoxing City","100552240","the-hi-tacs-on-cognitive-function-in-patients-with-schizophrenia-100552240",false,"NCT06470516","The Hi-tACS on Cognitive Function in Patients With Schizophrenia","The Impact of High-frequency Transcranial Alternating Current Stimulation (Hi-tACS) on Cognitive Function in Patients With Schizophrenia","Inclusion Criteria:\n\n1. Meets the diagnostic criteria for schizophrenia according to DSM-5.\n2. Age ≥ 18 years old.\n3. Right-handed.\n4. Willing to participate in this study and sign an informed consent form. If the participant is unable to read and sign the informed consent form due to lack of capacity, a legal guardian must act as a proxy during the informed consent process and sign the form.\n5. Clinically stable, receiving antipsychotic medication treatment with a stable dose for 4 weeks without any changes.\n6. Montreal Cognitive Assessment score ≥ 10 points.\n\nExclusion Criteria:\n\n1. Psychotic disorders caused by split affective disorder, bipolar disorder, intellectual disability, anxiety spectrum disorders, drugs, alcohol, and other psychoactive substances according to DSM-V diagnostic criteria.\n2. Those with severe or unstable organic diseases, with a history of brain tumors or epilepsy.\n3. Those who have received MECT or TMS treatment within 1 month before enrollment.\n4. Skin integrity at the electrode placement site is compromised. Allergy to electrode gel or adhesive.\n5. Implants of metal or electronic devices (such as pacemakers, cochlear implants, deep brain stimulators, aneurysm clips, internal fixation devices after ventriculoperitoneal shunt surgery, etc.).\n6. Participation in any other clinical trials within 1 month prior to baseline.\n7. Pregnant and lactating women.\n8. The investigator believes that there are inappropriate conditions for participating in this study.","ALL","18 Years",{"count":83,"type":84},100,"ESTIMATED","INTERVENTIONAL",[87],"NA","This study is a double-blind, randomized, controlled intervention study aimed at exploring whether high-frequency transcranial alternating current stimulation (Hi-tACS) can improve cognitive impairment in patients with schizophrenia.",[90],"Schizophrenia","2026-02-26",{"date":93,"type":94},"2026-03-02","ACTUAL",{"date":96,"type":94},"2024-04-01",{"date":98,"type":84},"2026-04-01",{"name":5,"class":6},2]