[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100356599":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":10,"locations":20,"responsibleParty":45,"collaborators":10,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":10,"maxAge":10,"enrollmentInfo":58,"targetDuration":61,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":23,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Universität des Saarlandes","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with Keratoconus",null,"Aim is to include as many Keratoconus patients as possible with the intention to elucidate how the disease begins and develops during lifetime.",[13],"Diagnostic Test: Topographic, tomographic and biomechanical analysis.",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Topographic, tomographic and biomechanical analysis.","The study is based upon data obtained during routine medical follow-ups using\n\n1. the Pentacam high resolution (Oculus, Wetzlar, Germany)\n2. the Corvis ST (Oculus, Wetzlar, Germany)\n3. the Anterior-Segment Optical Coherence Tomograph (AS-OCT) Casia 2 (Tomey, Nagoya, Japan)\n4. the Ocular Response Analyzer (Reichert Technologies, New York, USA).",[9],[21],{"facility":22,"status":23,"city":24,"state":25,"zip":26,"country":27,"countryCode":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"Department of Ophthalmology","RECRUITING","Homburg","Saarland","66421","Germany","DE",{"type":30,"coordinates":31},"Point",[32,33],7.33867,49.32637,{"lat":33,"lon":32},[36,41],{"name":37,"role":38,"phone":39,"phoneExt":10,"email":40},"Elias Flockerzi, PD Dr.med.","CONTACT","0049-6841-16-22302","elias.flockerzi@uks.eu",{"name":42,"role":38,"phone":43,"phoneExt":10,"email":44},"Berthold Seitz, Prof.Dr.med.","0049-6841-16-22387","berthold.seitz@uks.eu",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":49,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Elias Flockerzi","Principal Investigator, Resident of Ophthalmology","University Hospital, Saarland","100356599","the-homburg-keratoconus-center-hkc-100356599",false,"NCT03923101","The Homburg Keratoconus Center (HKC)","The Homburg Keratoconus Center (HKC) - a Keratoconus Observation Study","Inclusion Criteria:\n\n* All Keratoconus patients presenting in the department of ophthalmology, Saarland University Medical Center, Homburg, Saarland, Germany.\n\nExclusion Criteria:\n\n* Patients without Keratoconus.","ALL",{"count":59,"type":60},5000,"ESTIMATED","10 Years","OBSERVATIONAL","Aim of this study is to conduct longitudinal and cross-sectional analyses about the corneal ectatic disease Keratoconus based on data obtained from Keratoconus patients in the Homburg Keratoconus Center (HKC).\n\nThe Homburg Keratoconus Center (HKC) was founded in 2010 and, up to now, comprises more than 3,000 Keratoconus patients. Topographic, tomographic and biomechanic characteristics of the disease are being analyzed with the intention to elucidate how the disease begins and develops during lifetime.",[65],"Keratoconus",[65,67,68,69,70,71,72],"Crosslinking","Intracorneal ring segments","Gas-permeable rigid contact-lenses","Penetrating Keratoplasty","Deep anterior lamellar Keratoplasty","ABCD Grading System","2026-04-22",{"date":75,"type":76},"2026-04-27","ACTUAL",{"date":78,"type":76},"2011-01-01",{"date":80,"type":60},"2036-01-01",{"name":5,"class":6},1]