[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100508616":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":64,"collaborators":67,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":26,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":26,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":26,"overallStatus":47,"whyStopped":26,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Loyola University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Resilience, Stress, and Ethnicity (RiSE) program","EXPERIMENTAL","Resilience, Stress, and Ethnicity (RiSE) program is an 8-session weekly group-based intervention that integrates cognitive-behavioral strategies focused on the biopsychosocial impact of racism, racial identity development, and empowerment. RiSE has three primary components:\n\n1. processing and sharing experiences related to race based stress,\n2. psychoeducation on the biopsychosocial impact of racism,\n3. skill building and empowerment.",[13],"Behavioral: RiSE",{"label":15,"type":16,"description":17,"interventionNames":18},"Health Education Program (HEP)","ACTIVE_COMPARATOR","Health Education Program",[19],"Behavioral: HEP",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","RiSE","RiSE provides participants with a platform to share the emotional impact of race-based stress and to offer supportive listening to their peers. Participants explicitly discuss the experiences they have as African American women, taking into account the ways which the interaction between their racial and gender identities shapes their experiences. Facilitators review difficulties associated with addressing racism and unique experiences of Black women at interpersonal and structural levels, and provide evidence of strategies to promote effective communication and internal emotional regulation regarding experiences of racism. Facilitators provide psychoeducation on intersectionality, structural racism, overt racism, microaggressions, and internalized racism. Following this education, facilitators help participants utilize cognitive-behavioral strategies to understand consequent thoughts, feelings, and actions associated with such experiences.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"HEP","The HEP group will consist of classes focusing on wellness promotion. Expert speakers provide the HEP classes (e.g dietician, pharmacist).",[15],[32],{"name":33,"affiliation":34,"role":35},"Karen Saban, RN, PhD","Loyola University Chicago","PRINCIPAL_INVESTIGATOR",[37,41],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","773-508-3990","risestudy@luc.edu",{"name":42,"role":38,"phone":43,"phoneExt":26,"email":44},"Cara Joyce, PhD","464-220-9521","cjoyce6@luc.edu",[46],{"facility":34,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"RECRUITING","Maywood","Illinois","60153","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-87.84312,41.8792,{"lat":57,"lon":56},[60,63],{"name":33,"role":38,"phone":61,"phoneExt":26,"email":62},"708-216-1244","ksaban@luc.edu",{"name":33,"role":35,"phone":26,"phoneExt":26,"email":26},{"type":35,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Karen Saban","Professor",[68],{"name":69,"class":6},"Columbia University","100508616","the-impact-of-a-race-based-stress-reduction-intervention-100508616",false,"NCT05902741","The Impact of a Race-Based Stress Reduction Intervention","The Impact of a Race-Based Stress Reduction Intervention on Well-Being, Inflammation, and DNA Methylation in African American Women at Risk for Cardiometabolic Disease","Inclusion Criteria:\n\n* Between the ages of 50 and 75\n* Female\n* Post-menopausal (without menstrual period for at least 12 consecutive months)\n* Self-identified AA or Black\n* Able to write, read, speak English\n* Must have at least 1 of any of the following:\n\n  * Waist circumference \\>88 cm\n  * Systolic BP\\>130 mmHg and\u002F or diastolic BP\\>88 mmHg or on antihypertensive medications\n  * Diagnosed and\u002For being treated for hypercholesterolemia\n  * History of Type 2 diabetes\n\nExclusion Criteria:\n\n* History of myocardial infarction or ischemic heart disease\u002Fangina, stent placement, coronary artery bypass, left ventricular hypertrophy, congestive heart failure, or ischemic stroke\n* Any major immune-related disease (e.g., rheumatoid arthritis. lupus)\n* Use of immune-altering medications, such as glucocorticoids\n* Periodontal disease, bleeding gums, dental work in past 72 hours\n* Current smoker or has smoked in past 3 months\n* Active cancer\n* Active infection\n* Substance abuse\n* Cognitive or psychiatric disorder that would affect ability to participate in classes (Brief Screen for Cognitive Impairment total score of 8 or higher)","FEMALE","50 Years","75 Years",{"count":81,"type":82},300,"ESTIMATED","INTERVENTIONAL",[85],"NA","The goal of this clinical trial is to learn whether a stress reduction program called Resilience, Stress, and Ethnicity (RiSE) improves well-being, inflammation, and the epigenome in African American (AA) women who have risk factors for heart or metabolic disease.\n\nThe main question it aims to answer is whether an intervention that integrates cognitive-behavioral strategies focused on the impact that social stress, such as racism, has on the body, racial identity development, and empowerment.\n\nParticipants will placed in one of the two following groups:\n\n* The RiSE program will focus on teaching participants how to reduce their stress levels and will meet online weekly for approximately 2 hours each week for 8 consecutive weeks.\n* The Health Education program will include education on how to improve general health and will meet online weekly for approximately 2 hours each week for 8 consecutive weeks.\n\nParticipants will provide saliva to measure cytokines and DNA methylation (DNAm), complete questionnaires, and have blood pressure, heart rate, and weight measured at the following clinic visits:\n\n1. Prior to starting the intervention\n2. Mid-way through the intervention (Week 4)\n3. End of the intervention (Week 8)\n4. Six (6) months after the completion of the intervention",[88,89,90],"Racism","Stress","Inflammation","2025-09-02",{"date":93,"type":94},"2025-09-09","ACTUAL",{"date":96,"type":94},"2023-10-18",{"date":98,"type":82},"2028-01-31",{"name":5,"class":6},1]