[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645157":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":7,"locations":11,"responsibleParty":32,"collaborators":7,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":40,"acronym":7,"eligibilityCriteria":41,"healthyVolunteers":38,"sex":42,"minAge":43,"maxAge":7,"enrollmentInfo":44,"targetDuration":47,"studyType":48,"phases":7,"briefSummary":49,"conditions":50,"keywords":7,"overallStatus":14,"whyStopped":7,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":61},{"fullName":5,"class":6},"Xiangya Hospital of Central South University","OTHER",null,[9],{"type":6,"name":10,"description":10,"armGroupLabels":7,"otherNames":7},"No intervention measures",[12],{"facility":13,"status":14,"city":15,"state":16,"zip":17,"country":18,"countryCode":19,"cosmosGeoPoint":20,"geoPoint":25,"contacts":26},"Xiangya Hospital Central South University","RECRUITING","Changsha","Hunan","410008","China","CN",{"type":21,"coordinates":22},"Point",[23,24],112.97087,28.19874,{"lat":24,"lon":23},[27],{"name":28,"role":29,"phone":30,"phoneExt":7,"email":31},"Yuanyuan Li, Doctor","CONTACT","+8619976695523","Leeround@csu.edu.cn",{"type":33,"investigatorFullName":34,"investigatorTitle":35,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Yuanyuan Li","Chief Physician","100645157","the-impact-of-anxietydepression-on-the-efficacy-of-asthma-control-drugs-and-the-construction-of-a-predictive-model-for-the-risk-of-acute-asthma-attacks-100645157",false,"NCT07679321","The Impact of Anxiety\u002FDepression on the Efficacy of Asthma Control Drugs and the Construction of a Predictive Model for the Risk of Acute Asthma Attacks","Inclusion Criteria:\n\n* Diagnosis of asthma according to the Global Initiative for Asthma (GINA) 2024 criteria.\n* Male or female patients aged 14 years or older.\n* Complete clinical data available.\n* Newly diagnosed asthma or stable asthma.\n* Receiving asthma controller medication.\n\nExclusion Criteria:\n\n* History of major lung diseases other than asthma, congestive heart failure, cor pulmonale, or recent cardiac or thoracic surgery.\n* Incomplete medical records.\n* Cognitive impairment or inability to complete psychological scale assessments.\n* Clinically diagnosed acute or chronic mental disorders, such as bipolar disorder or schizophrenia.\n* Current use of antidepressant or anti-anxiety medications.\n* Pregnancy or lactation.","ALL","14 Years",{"count":45,"type":46},256,"ESTIMATED","1 Year","OBSERVATIONAL","The goal of this clinical trial is to explore the impact of anxiety\u002Fdepression on the efficacy of asthma controller medications and to develop a risk prediction model for asthma acute exacerbations in patients with asthma. It will also analyze the association between anxiety\u002Fdepression severity and asthma severity. The main questions it aims to answer are:\n\nDoes anxiety\u002Fdepression affect the therapeutic effect of asthma controller medications (e.g., asthma control level)? Can a reliable risk prediction model for asthma acute exacerbations be established based on anxiety\u002Fdepression and other relevant factors? Researchers will conduct a prospective observational study to collect and analyze data from participants, without additional interventions beyond standard clinical care, to explore the above research questions.\n\nParticipants will:\n\nComplete baseline assessments, including demographic information collection, medical history review, lung function tests, anxiety\u002Fdepression evaluations (via GAD-7 and PHQ-9 scales), and provide biological samples (induced sputum, feces, blood) Undergo follow-up visits at 3, 6, 12, 18, and 24 months after baseline Report asthma symptoms, acute exacerbation events, and cooperate with required clinical checkups during follow-up",[51],"Anxiety\u002FDepression and Asthma","2026-06-28",{"date":54,"type":55},"2026-07-01","ACTUAL",{"date":57,"type":55},"2024-12-01",{"date":59,"type":46},"2027-12-30",{"name":5,"class":6},1]