[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604700":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":42,"responsibleParty":59,"collaborators":26,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":26,"eligibilityCriteria":68,"healthyVolunteers":65,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":26,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Anhui Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental group","ACTIVE_COMPARATOR","Active stimulation: deliver 20 minutes of beta-band tACS intervention.",[13],"Device: Beta-frequency transcranial alternating current stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","SHAM_COMPARATOR","Sham stimulation will be administered with identical treatment parameters, duration, and number of sessions as the active intervention. For the control group, the current will be ramped up to 2 mA and then ramped down to 0 mA within the first 30 seconds.",[19],"Device: sham beta-frequency transcranial alternating current stimulation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Beta-frequency transcranial alternating current stimulation","Active beta-frequency transcranial alternating current stimulation: 20 Hz tACS delivered through a 4×1-ring high-definition electrode montage centered on left DLPFC (F3), 2 mA peak-to-peak, 100 % intensity, gradually ramped up over 30 s, maintained for 20 min, then ramped down over 30 s; two sessions per day with at least 4 h between sessions, repeated for 7 consecutive days (14 total sessions).",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"sham beta-frequency transcranial alternating current stimulation","Sham transcranial alternating current stimulation: identical 4×1-ring high-definition electrode montage centered on left DLPFC (F3), 2 mA peak-to-peak current ramped up over 30 s and immediately ramped down to 0 mA, followed by 19.5 min of no stimulation to match the 20-min session duration of active tACS; delivered twice daily (≥4 h apart) for 7 consecutive days (14 total sessions).",[15],[32],{"name":33,"affiliation":34,"role":35},"Lei Zhang, doctor","School of Mental Health and Psychological Sciences, Anhui Medical University","STUDY_DIRECTOR",[37],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Meiling Wang, bachelor","CONTACT","+86 136 4707 0027","1605280093@qq.com",[43],{"facility":34,"status":44,"city":45,"state":46,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Hefei","Anhui","China","CN",{"type":50,"coordinates":51},"Point",[52,53],117.28083,31.86389,{"lat":53,"lon":52},[56],{"name":33,"role":39,"phone":57,"phoneExt":26,"email":58},"+86 138 6612 9450","anyipsychology@163.com",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Wang Meiling","student","100604700","the-impact-of-beta-band-transcranial-alternating-current-stimulation-tacs-on-impulse-inhibition-in-adolescents-with-non-suicidal-self-injury-100604700",false,"NCT07152925","The Impact of Beta-band Transcranial Alternating Current Stimulation (tACS) on Impulse Inhibition in Adolescents With Non-suicidal Self-injury","Inclusion Criteria:\n\n* 1\\) Meet the proposed diagnostic criteria for non-suicidal self-injury (NSSI) in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), with ≥5 documented self-injury episodes and at least one incident within the past month as assessed by the Adolescent Non-Suicidal Self-Injury Assessment Questionnaire (ANSAQ); 2) Aged 12-18 years; 3) Right-handed; 4) Possess formal education experience sufficient to comprehend experimental protocols; 5) Normal or corrected-to-normal binocular visual acuity; 6) Voluntarily participate with legal guardians providing written informed consent.\n\nExclusion Criteria:\n\n* 1\\) Montreal Cognitive Assessment (MoCA) score \\\u003C 26; 2) History of suicide attempt(s); 3) Medical history of epilepsy, brain surgery, intracranial tumors, metal implants in the skull, or clinically significant head trauma; 4) History of substance use disorder, brain injury, severe somatic diseases, psychiatric disorders, or comorbid DSM-5 psychiatric conditions; 5) Prior receipt of transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), or repetitive transcranial magnetic stimulation (rTMS) within the past 3 months","ALL","12 Years","22 Years",{"count":73,"type":74},60,"ESTIMATED","INTERVENTIONAL",[77],"NA","This clinical trial aims to determine whether beta-band transcranial alternating current stimulation (tACS) can improve impulse inhibition in adolescents with non-suicidal self-injury (NSSI) and to evaluate its safety. The primary questions it seeks to answer are:\n\n* Can beta-band tACS significantly reduce the frequency of self-injury and scores on impulsivity scales in adolescents with NSSI?\n* What discomfort or medical issues may participants experience during tACS intervention?\n\nResearchers will compare beta-band tACS with sham stimulation (a procedure that mimics the real stimulation without delivering effective current) to verify its efficacy.\n\nParticipants will:\n\n* Receive two sessions of either tACS or sham stimulation daily, spaced 4 hours apart, for 7 consecutive days (14 sessions in total).\n* Undergo scale assessments, behavioral tasks, and eye-tracking tests before and after the intervention.\n* Record any self-injury episodes and adverse reactions, with continuous monitoring and psychological support provided by a professional team.",[80,81],"Depression Disorders","Non-suicidal Self-injury",[83,84,85],"Depression","non-suicidal self-injury","transcranial alternating current stimulation","2025-08-26",{"date":88,"type":89},"2025-09-03","ACTUAL",{"date":91,"type":89},"2025-03-01",{"date":93,"type":74},"2026-05-31",{"name":5,"class":6},1]