[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613920":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":43,"responsibleParty":82,"collaborators":84,"id":92,"slug":93,"hasResults":94,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":11,"eligibilityCriteria":98,"healthyVolunteers":94,"sex":99,"minAge":100,"maxAge":101,"enrollmentInfo":102,"targetDuration":11,"studyType":105,"phases":106,"briefSummary":108,"conditions":109,"keywords":114,"overallStatus":121,"whyStopped":11,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":131},{"fullName":5,"class":6},"University of Alabama, Tuscaloosa","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Brief Behavioral Treatment for Insomnia (BBTI)","EXPERIMENTAL",null,[13],"Behavioral: BBTI",{"label":15,"type":16,"description":11,"interventionNames":17},"Brief Mindfulness Treatment (BMT)","ACTIVE_COMPARATOR",[18],"Behavioral: BMT",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"BEHAVIORAL","BBTI","4-week intervention delivered via telephone (once a week for 30 minutes)",[9],{"type":21,"name":26,"description":23,"armGroupLabels":27,"otherNames":11},"BMT",[15],[29],{"name":30,"affiliation":31,"role":32},"Dr. Shameka L Cody, PhD, AGNP-C, PMHNP-BC, FAAN","The University of Alabama Capstone College of Nursing","PRINCIPAL_INVESTIGATOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":11,"email":38},"Dr. Shameka L. Cody, PhD, AGNP-C, PMHNP-BC, FAAN","CONTACT","205 348 3374","slcody@ua.edu",{"name":40,"role":36,"phone":41,"phoneExt":11,"email":42},"Dr. Stephen Justin Thomas, PhD, DBSM, FSBSM","205 934 3367","sjthoma@uabmc.edu",[44,66],{"facility":45,"status":11,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"The University of Alabama at Birmingham","Birmingham","Alabama","35233","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-86.80249,33.52066,{"lat":55,"lon":54},[58,59,63],{"name":40,"role":36,"phone":41,"phoneExt":11,"email":42},{"name":60,"role":36,"phone":61,"phoneExt":11,"email":62},"Dr. David E. Vance, PhD, MGS, FAAN","205 934 7589","devance@uab.edu",{"name":64,"role":65,"phone":11,"phoneExt":11,"email":11},"Dr. Shu Chen, PhD","SUB_INVESTIGATOR",{"facility":67,"status":11,"city":68,"state":47,"zip":69,"country":49,"countryCode":50,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"The University of Alabama","Tuscaloosa","35401",{"type":52,"coordinates":71},[72,73],-87.56917,33.20984,{"lat":73,"lon":72},[76,77,80],{"name":35,"role":36,"phone":37,"phoneExt":11,"email":38},{"name":78,"role":36,"phone":11,"phoneExt":11,"email":79},"Dr. Mary L. Jacobs, PhD, MSPH, ABPP","jacob008@ua.edu",{"name":81,"role":65,"phone":11,"phoneExt":11,"email":11},"Dr. Chuong Bui, PhD",{"type":83,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR",[85,87,90],{"name":86,"class":6},"University of Alabama at Birmingham",{"name":88,"class":89},"National Institute on Aging (NIA)","NIH",{"name":91,"class":89},"NIH Office of AIDS Research (OAR)","100613920","the-impact-of-brief-behavioral-treatment-for-insomnia-versus-brief-mindfulness-treatment-on-cognition-and-sleep-health-in-adults-age-50-with-hiv-100613920",false,"NCT07272863","The Impact of Brief Behavioral Treatment for Insomnia Versus Brief Mindfulness Treatment on Cognition and Sleep Health in Adults (Age 50+) With HIV","The Impact of BBTI on Cognition and Sleep Health in Older Adults With HIV","Inclusion Criteria:\n\n* must be age 50 or older\n* have a DSM-5 diagnostic criteria for insomnia including sleep difficulty that occurs at least 3 times per week and has been a problem for at least 3 consecutive months (indicated on the Structured Clinical Interview for Sleep Disorders, SCISD) during telephone screening\n* have a confirmed HIV diagnosis and a prescribed ART regimen for at least 12 months.\n\nExclusion Criteria:\n\n* unable to speak English\n* have a reported or documented (in medical records) diagnosis of AD or dementia\n* have severe neurocognitive impairment (\\>7 errors on the Short Portable Mental Status Questionnaire, SPMSQ) during telephone screening\n* have a history of a stroke\n* currently undergoing radiation\u002Fchemotherapy\n* reports a history of brain trauma with loss of consciousness greater than 30 minutes\n* have a learning disability\n* have a documented diagnosis of sleep apnea (in medical records)\n* reports use of a continuous positive airway pressure machine\n* have been identified as high risk for moderate to severe sleep apnea (Snoring, Tiredness, Observed sleep apnea, Pressure, BMI, Age, Neck circumference, and Gender, STOP BANG ≥ 5) during telephone screening\n* have restless leg syndrome and\u002For have narcolepsy\n* have a documented history of bipolar disorder or psychotic disorder\n* not be receiving efavirenz as part of their current ART regimen","ALL","50 Years","99 Years",{"count":103,"type":104},214,"ESTIMATED","INTERVENTIONAL",[107],"NA","The goal of this clinical trial is to examine the effects of a telephone-delivered Brief Behavioral Treatment Insomnia (BBTI) versus a Brief Mindfulness Treatment (BMT) on cognitive and sleep outcomes in older adults with HIV. The main questions it aims to answer are:\n\nWhat are the effects of BBTI vs BMT on self-reported and observed sleep outcomes in older adults with HIV and insomnia up to 1-year post-intervention? What are the effects of BBTI vs BMT on self-reported and observed cognitive comes in older adults with HIV and insomnia up to 1-year post-intervention? What is the association between Alzheimer's Disease biomarkers and sleep and cognitive outcomes in older adults with HIV receiving BBTI vs BMT?\n\nParticipants will:\n\n* Complete 4 weeks of telephone-delivered BBTI or BMT\n* Attend baseline, post-intervention, and 1-year post in-person visits for sleep and cognitive assessments\n* Have blood collected at all three time points",[110,111,112,113],"Insomnia","Cognition","Aging","HIV",[115,116,117,113,118,119,120],"insomnia","cognition","older adults","Alzheimer's Disease","brief behavioral treatment","randomized control trial","NOT_YET_RECRUITING","2026-05-07",{"date":124,"type":125},"2026-05-08","ACTUAL",{"date":127,"type":104},"2026-05",{"date":129,"type":104},"2030-09",{"name":5,"class":6},2]