[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589205":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":43,"responsibleParty":62,"collaborators":26,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":26,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":92,"overallStatus":46,"whyStopped":26,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"KU Leuven","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Drink enriched with short-chain fatty acids","ACTIVE_COMPARATOR","Treatment with enriched drink",[13],"Dietary Supplement: with short-chain fatty acids enriched drink",{"label":15,"type":16,"description":17,"interventionNames":18},"Control drink","PLACEBO_COMPARATOR","Treatment with control drink",[19],"Dietary Supplement: unenriched oat drink",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","with short-chain fatty acids enriched drink","Oat-based drink enriched with 15 g\u002FL short-chain fatty acids",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"unenriched oat drink","Oat-based drink",[15],[32],{"name":33,"affiliation":5,"role":34},"Kristin Verbeke, Prof.","PRINCIPAL_INVESTIGATOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Riet Rosseel, Msc","CONTACT","+3216373428","riet.rosseel@kuleuven.be",{"name":33,"role":38,"phone":26,"phoneExt":26,"email":42},"kristin.verbeke@kuleuven.be",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"KU Leuven\u002F UZ Leuven","RECRUITING","Leuven","Vlaams-Brabant","3000","Belgium","BE",{"type":53,"coordinates":54},"Point",[55,56],4.70093,50.87959,{"lat":56,"lon":55},[59,60,61],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},{"name":33,"role":38,"phone":26,"phoneExt":26,"email":42},{"name":33,"role":34,"phone":26,"phoneExt":26,"email":26},{"type":34,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Kristin Verbeke","Prof.","100589205","the-impact-of-daily-intake-of-short-chain-fatty-acids-on-cardiometabolic-risk-factors-in-individuals-at-risk-for-metabolic-syndrome-100589205",false,"NCT06951386","The Impact of Daily Intake of Short-chain Fatty Acids on Cardiometabolic Risk Factors in Individuals at Risk for Metabolic Syndrome","The Impact of 12 Weeks Intervention With Plant-based Oat Drink Rich in Short-chain Fatty Acids on Postprandial Lipidemia in Individuals at Risk for Metabolic Syndrome","12OATS","Inclusion Criteria:\n\n* male and female participants\n* central obesity ( BMI ≥ 25 kg\u002Fm² or waist circumference ≥ 80 cm for women\u002F ≥ 94 cm for men)\n* One additional risk factor for metabolic syndrome:\n\n  1. Insulin resistance (HOMA-IR ≥ 1.7 or fasting glucose ≥ 100 mg\u002Fdl)\n  2. Triglyceride concentration ≥ 150 mg\u002Fdl\n  3. HDL-cholesterol \\\u003C 40 mg\u002Fdl for women\u002F \\\u003C 50 mg\u002Fdl for men\n  4. Systolic blood pressure ≥ 130 mmHg or diastolic blood pressure ≥ 85 mmHg\n* knowledge of English\n\nExclusion Criteria:\n\n* gastrointestinal disorders such as IBD, IBS, celiac disease, chronic constipation, chronic diarrhoea\n* history of abdominal surgery, except for appendectomy\n* Use of antihypertensive, cholesterol lowering, glucose-regulating drugs and corticosteroids\n* Use of antibiotics 3 months prior to the start or during the study\n* Use of probiotics and prebiotics 2 weeks prior to the start of the study\u002F during the study\n* Being on weight loss, gluten-free, lactose-free or vegan diet\n* Pregnancy, lactation or wish to become pregnant\n* Previous or current substance\u002F alcohol dependence or abuse\n* Hyper- or hypothyroidism\n* Allergy or intolerance to oat milk","ALL","18 Years","65 Years",{"count":77,"type":78},50,"ESTIMATED","INTERVENTIONAL",[81],"NA","During this study, the effect of short-chain fatty acids on blood lipaedemia, glycemia, anthropometrics, blood pressure and energy expenditure will be investigated.",[84,85,86,87,88,89,90,91],"Energy Expenditure","Metabolic Syndrome","Anthropometry","Body Composition","Glycemia","Lipaemia","Metabolomics","Blood Pressure",[93,94],"short-chain fatty acids","cardiometabolic health","2025-04-30",{"date":97,"type":98},"2025-05-04","ACTUAL",{"date":100,"type":98},"2025-02-11",{"date":102,"type":78},"2026-02-28",{"name":5,"class":6},1]