[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573775":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":10,"centralContacts":33,"locations":42,"responsibleParty":67,"collaborators":10,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":10,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":10,"enrollmentInfo":80,"targetDuration":83,"studyType":84,"phases":10,"briefSummary":85,"conditions":86,"keywords":94,"overallStatus":100,"whyStopped":10,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Aalborg University Hospital","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Emergency rooms in North Denmark Region",null,"Data from all emergency rooms in North Denmark Region will be retrieved. This includes sites at Aalborg University Hospital and North Denmark Regional Hospital.",[13],"Diagnostic Test: De-implementation of Urinary Dipsticks",{"label":15,"type":10,"description":16,"interventionNames":17},"Control hospital in Central Denmark Region","The investigators aim to retrieve data from a hospital outside the North Denmark Region that continues to use urine dipsticks. Specifically, the investigators plan to collect data from Aarhus University Hospital, the largest hospital in the Central Denmark Region.",[18],"Other: Usual practice with no intervention",{"label":20,"type":10,"description":21,"interventionNames":22},"Control urine cultures from general practice","The count of urine cultures ordered in the primary sector outside hospitals in the North Denmark Region (general practice), where dipsticks remain in use, will serve as a control.",[18],[24,29],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"DIAGNOSTIC_TEST","De-implementation of Urinary Dipsticks","In August 2023 \u002F February 2024, urinary dipsticks were de-implemented in hospitals across the North Denmark Region. Using registry-based data, the investigators aim to evaluate the clinical impact of this decision.",[9],{"type":6,"name":30,"description":31,"armGroupLabels":32,"otherNames":10},"Usual practice with no intervention","In hospitals within the Central Denmark Region and in the primary care sector, urinary dipsticks have not been de-implemented and remain in use. Registry-based data from these settings will serve as a control.",[15,20],[34,39],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},"Peter Preben Eggertsen, MD, PhD","CONTACT","+45 97660566","p.eggertsen@rn.dk",{"name":40,"role":36,"phone":37,"phoneExt":10,"email":41},"Jacob Bodilsen, MD, PhD","jacob.bodilsen@rn.dk",[43,56],{"facility":5,"status":10,"city":44,"state":10,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Aalborg","9000","Denmark","DK",{"type":49,"coordinates":50},"Point",[51,52],9.9187,57.048,{"lat":52,"lon":51},[55],{"name":40,"role":36,"phone":37,"phoneExt":10,"email":41},{"facility":57,"status":10,"city":58,"state":10,"zip":59,"country":46,"countryCode":47,"cosmosGeoPoint":60,"geoPoint":64,"contacts":65},"North Denmark Regional Hospital","Hjørring","9800",{"type":49,"coordinates":61},[62,63],9.98229,57.46417,{"lat":63,"lon":62},[66],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},{"type":68,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Jacob Bodilsen","Sponsor-Investigator","100573775","the-impact-of-de-implementing-urine-dipsticks-for-diagnosis-of-utis-in-hospitals-100573775",false,"NCT06750666","The Impact of De-implementing Urine Dipsticks for Diagnosis of UTIs in Hospitals","The Impact of De-implementing Urine Dipsticks for Diagnosis of Urinary Tract Infections in the North Denmark Region: An Interrupted Time-series Analysis","Inclusion Criteria:\n\n* All patients admitted to emergency rooms (≥18 years) from 2019 and forward.\n\nExclusion Criteria:\n\n* Patients directly admitted to an inpatient unit without first visiting an emergency room are excluded from the study.\n* For the primary analysis, only the first admission will be included; subsequent admissions will be excluded.","ALL","18 Years",{"count":81,"type":82},480000,"ESTIMATED","30 Days","OBSERVATIONAL","The goal of this interrupted time-series analysis is to evaluate the impact of the de-implementation of urine dipsticks as a diagnostic tool for urinary tract infections (UTIs) in hospitalized patients in the North Denmark Region. The main question it aims to answer is:\n\nHow does de-implementation of urine dipsticks affect the diagnosis and management of UTIs and related disorders?\n\nSpecifically, does it change the following parameters:\n\n* Number and severity of UTI infections (lower and upper UTI, non-severe and severe)\n* Antibiotic prescription (overall, antibiotic classes, administration routes, duration, dosages)\n* Number of urine cultures and number of positive urine cultures\n* Risks of admission to intensive care units and 30-day mortality\n* Risk of drug toxicity\n* Length of hospital stay\n* Risk of admission to intensive care unit\n* 30-day risk of readmission after discharge\n* 6-month risks of Clostridioides difficile enterocolitis and de novo antimicrobial resistance in cultures obtained during routine clinical care.\n\nResearchers hypothesize that de-implementing urine dipsticks will lead to a reduced frequency of diagnosed cystitis, reduced antibiotic use, and fewer urine cultures without negatively affecting patient mortality or readmission risk.\n\nResearchers will compare the outcomes before and after the discontinuation of urine dipsticks across hospitals in the North Denmark Region. Furthermore, results will be compared to another Danish administrative healthcare region where dipsticks are still in use as well as urine culture data from the primary sector in the North Denmark Region.\n\nSince this is a registry-based observational study utilizing data from the electronic patient record system in the North Denmark Region, no direct contact will be made with participants.",[87,88,89,90,91,92,93],"Urinary Tract Infections","Diagnostic Techniques and Procedures","Point-of-Care Testing","Anti-Bacterial Agents","Registry","Clinical Decision-making","Urinalysis",[95,87,96,97,98,99],"Urine Dipstick De-implementation","Hospital","Registry-Based Study","Clinical Impact","urine dipsticks","NOT_YET_RECRUITING","2025-09-30",{"date":103,"type":104},"2025-10-01","ACTUAL",{"date":106,"type":82},"2025-12",{"date":108,"type":82},"2026-12",{"name":69,"class":6},2]