[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100531817":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":12,"centralContacts":32,"locations":41,"responsibleParty":59,"collaborators":61,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":12,"eligibilityCriteria":71,"healthyVolunteers":72,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":12,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":44,"whyStopped":12,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"University School of Physical Education, Krakow, Poland","OTHER",[8,13,19,23],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","NO_INTERVENTION","The control group will not undergo the training program.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"LHTL (live high - train low)","EXPERIMENTAL","Training performed under normoxic conditions (223m), stay and sleep in normobaric hypoxic conditions (3000m) and thermoneutral conditions (21°C) and constant humidity (40%).",[18],"Other: Exercise and environmental conditions",{"label":20,"type":15,"description":21,"interventionNames":22},"LLTH (live low - train high)","Training performed under normobaric hypoxia conditions (3000m), stay and sleep in normoxic conditions (223m) and thermoneutral conditions (21°C) and constant humidity (40%).\n\nwill stay and sleep in normoxic (223m), and train in normobaric hypoxia (3000m)",[18],{"label":24,"type":15,"description":25,"interventionNames":26},"LLTL (live low - train low)","Training performed and stay and sleep in normoxic conditions (223m) and thermoneutral conditions (21°C) and constant humidity (40%).",[18],[28],{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":12},"Exercise and environmental conditions","Participants will engage in interval training and will reside and sleep at different altitudes for a period of 4 weeks. Aerobic and anaerobic capacity tests and an eccentric exercise test will be performed before and after the training intervention. Before and after the training program, somatic measurements will also be taken. Before and after the first and last workout, blood will be drawn for biochemical analysis.",[14,20,24],[33,38],{"name":34,"role":35,"phone":36,"phoneExt":12,"email":37},"Anna Radoń, MSc","CONTACT","+45126831142","anna.radon@awf.krakow.pl",{"name":39,"role":35,"phone":12,"phoneExt":12,"email":40},"Anna Kałuża, MSc","anna.kaluza@doctoral.awf.krakow.pl",[42],{"facility":43,"status":44,"city":45,"state":12,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"University School of Physical Education in Cracow","RECRUITING","Krakow","31-571","Poland","PL",{"type":50,"coordinates":51},"Point",[52,53],19.93658,50.06143,{"lat":53,"lon":52},[56],{"name":57,"role":35,"phone":58,"phoneExt":12,"email":37},"Anna Radon, Msc","48 12 6831142",{"type":60,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR",[62],{"name":63,"class":64},"Ministry of Education and Science,Poland","UNKNOWN","100531817","the-impact-of-physical-training-under-normobaric-hypoxia-on-oxidative-stress-level-inflammatory-state-intestinal-damage-and-mitochondrial-metabolism-in-young-males-100531817",false,"NCT06204731","The Impact of Physical Training Under Normobaric Hypoxia on Oxidative Stress Level, Inflammatory State, Intestinal Damage, and Mitochondrial Metabolism in Young Males","The Influence of Physical Training in Normobaric Hypoxia on Prooxidant-Antioxidant Imbalance, Inflammatory Marker Levels, Intestinal Damage Degree, and Mitochondrial Energy Release Rate in Young Non-trained Males","Inclusion Criteria:\n\n* no known metabolic diseases, no contraindications to physical exercise and no history of high altitude sickness stated in interview. A medical examination (including ECG, blood and urine tests) is required.\n\nExclusion Criteria:\n\n* changes in diet during the experiment, smoking and abuse of alcohol and\u002For other stimulants.",true,"MALE","19 Years","29 Years",{"count":77,"type":78},50,"ESTIMATED","INTERVENTIONAL",[81],"NA","* Cognitive assessment of the influence of a 4-week proprietary training program under normobaric hypoxia conditions on the levels of inflammatory markers, disturbances in prooxidant-antioxidant balance, degree of intestinal damage, and mitochondrial energy production rate in young sedentary males.\n* Applied objective: Development of practical training guidelines utilizing training in normobaric hypoxia conditions to enhance mechanisms related to oxygen transport, adaptive changes within the immune system, body's antioxidant capacity, gut permeability, substrate utilization efficiency, and mitochondrial function for coaches and athletes.",[84],"Hypoxia, Altitude",[86,87,88,89,90,91,92],"inflammation","oxidative stress","intestinal damage","muscle damage","mitochondrial metabolism","normobaric hypoxia","training","2024-01-03",{"date":95,"type":96},"2024-01-12","ACTUAL",{"date":98,"type":96},"2023-02-01",{"date":100,"type":78},"2026-12",{"name":5,"class":6},1]