[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100477865":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":39,"centralContacts":44,"locations":50,"responsibleParty":104,"collaborators":48,"id":106,"slug":107,"hasResults":108,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":48,"eligibilityCriteria":112,"healthyVolunteers":108,"sex":113,"minAge":114,"maxAge":48,"enrollmentInfo":115,"targetDuration":48,"studyType":118,"phases":119,"briefSummary":121,"conditions":122,"keywords":48,"overallStatus":53,"whyStopped":48,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":136},{"fullName":5,"class":6},"Thomas Jefferson University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group I (pulmonary vein first approach procedure)","ACTIVE_COMPARATOR","Patients undergo pulmonary vein first approach surgical procedure on day of surgery.",[13],"Procedure: Pulmonary Artery-First Surgical Technique",{"label":15,"type":10,"description":16,"interventionNames":17},"Group II (pulmonary artery first surgical procedure)","Patients undergo pulmonary artery first approach surgical procedure on day of surgery.",[18],"Procedure: Biospecimen Collection",[20,31],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Pulmonary Artery-First Surgical Technique","Undergo pulmonary artery first surgical technique",[9],[26,27,28,29,30],"Artery-First Technique","A-First Technique","Lung Cancer Artery-First Surgical Technique","Artery-First Surgical Technique","Artery-First Ligation",{"type":21,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"Biospecimen Collection","Correlative studies",[15],[36,37,38],"Biological Sample Collection","Biospecimen Collected","Specimen Collection",[40],{"name":41,"affiliation":42,"role":43},"Tyler Grenda, 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MD","215-481-4000",{"type":105,"investigatorFullName":48,"investigatorTitle":48,"investigatorAffiliation":48,"oldNameTitle":48,"oldOrganization":48},"SPONSOR","100477865","the-impact-of-surgical-technique-on-circulating-tumor-dna-in-stage-i-iii-non-small-cell-lung-cancer-100477865",false,"NCT05502523","The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer","The Impact of Surgical Technique on Circulating Tumor DNA in Early-Stage Non-Small Cell Lung Cancer","Inclusion Criteria:\n\n* Any patients 18 years of age or older with confirmed or suspected early-stage (stage I-III) NSCLC\n* Eligible and scheduled for surgical anatomic lung resection (e.g. lobectomy or segmentectomy) as routine clinical care for their disease\n\nExclusion Criteria:\n\n* Previous cancer diagnosis within 5 years (except ductal carcinoma in situ \\[DCIS\\] of the breast, superficial bladder cancer, non-melanoma skin primary, other malignancy that does not require treatment).\n* Preoperative chemotherapy, immunotherapy, or radiation therapy\n* Receipt of perioperative blood transfusion","ALL","18 Years",{"count":116,"type":117},100,"ESTIMATED","INTERVENTIONAL",[120],"NA","This clinical trial compares the effect of pulmonary vein-first surgical technique to pulmonary artery-first surgical technique in decreasing circulating tumor cell deoxyribonucleic acid (ctDNA) in patients with stage I-III non-small cell lung cancer. Pulmonary vein first and pulmonary artery first surgical techniques are standard surgical techniques for the division of the blood vessels during lung resection surgery. Pulmonary vein-first surgical technique may reduce the risk of shedding tumor cells during surgery and influence long term overall survival.",[123,124,125,126],"Lung Non-Small Cell Carcinoma","Stage I Lung Cancer AJCC v8","Stage II Lung Cancer AJCC v8","Stage III Lung Cancer AJCC v8","2026-01-21",{"date":129,"type":130},"2026-01-23","ACTUAL",{"date":132,"type":130},"2022-08-31",{"date":134,"type":117},"2029-01-01",{"name":5,"class":6},4]