[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638036":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":30,"collaborators":10,"id":34,"slug":35,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":38,"acronym":10,"eligibilityCriteria":39,"healthyVolunteers":36,"sex":40,"minAge":41,"maxAge":10,"enrollmentInfo":42,"targetDuration":10,"studyType":45,"phases":10,"briefSummary":46,"conditions":47,"keywords":10,"overallStatus":20,"whyStopped":10,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":59},{"fullName":5,"class":6},"Shaare Zedek Medical Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Adults With Heart Failure Undergoing Diuresis",null,"Adults hospitalized with heart failure and fluid overload who undergo standard diuretic therapy. Participants are evaluated using sleep monitoring (WatchPAT), neck circumference measurements, and clinical assessments before diuresis (on the first night of hospitalization) and after diuresis, when the treating cardiologist determines that the patient is no longer fluid overloaded.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Itshak Amsalem, MD","CONTACT","+972508229454","itshak1a@gmail.com",[19],{"facility":5,"status":20,"city":21,"state":10,"zip":10,"country":22,"countryCode":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":10},"RECRUITING","Jerusalem","Israel","IL",{"type":25,"coordinates":26},"Point",[27,28],35.21633,31.76904,{"lat":28,"lon":27},{"type":31,"investigatorFullName":32,"investigatorTitle":33,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Itshak Amsalem","Principal Investigator","100638036","the-impact-of-volume-overload-on-obstructive-sleep-apnea-in-patients-with-congestive-heart-failure-100638036",false,"NCT07601724","The Impact of Volume Overload on Obstructive Sleep Apnea in Patients With Congestive Heart Failure","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Hospitalized with decompensated heart failure and clinical evidence of fluid overload\n* Diagnosis of heart failure (reduced or preserved ejection fraction)\n* Clinically indicated for diuretic therapy\n* Able to undergo sleep apnea assessment using the WatchPAT device\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Known central sleep apnea as the predominant sleep-disordered breathing type\n* Current treatment with continuous positive airway pressure (CPAP)\n* Acute respiratory failure requiring mechanical ventilation\n* Conditions preventing proper use of the WatchPAT device (e.g., severe hand or finger injury)\n* Hemodynamic instability precluding participation\n* Pregnancy","ALL","18 Years",{"count":43,"type":44},50,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn how removing extra fluid from the body (diuresis) affects sleep apnea in adults hospitalized with heart failure.\n\nThe main questions it aims to answer are:\n\nDoes sleep apnea severity improve after fluid removal? Is the improvement in sleep apnea related to the amount of fluid removed? Do changes in neck size reflect changes in sleep apnea severity?\n\nParticipants admitted to the hospital with heart failure and fluid overload will take part in this study.\n\nParticipants will:\n\nUse a wearable sleep monitoring device (WatchPAT) on the first night of hospitalization Use the device again after fluid removal, when the treating cardiologist determines that the patient is no longer fluid overloaded Have their neck circumference measured before and after fluid removal Have their weight and fluid balance recorded during hospitalization Have routine blood tests and clinical assessments as part of standard care\n\nResearchers will compare each participant's results before and after fluid removal to see if sleep apnea improves and whether these changes are linked to fluid removal and changes in neck circumference.",[48,49],"Heart Failure","Obstructive Sleep Apnea (OSA)","2026-05-19",{"date":52,"type":53},"2026-05-22","ACTUAL",{"date":55,"type":53},"2026-01-01",{"date":57,"type":44},"2027-06",{"name":32,"class":6},1]