[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642063":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":37,"locations":23,"responsibleParty":43,"collaborators":23,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":23,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":73,"whyStopped":23,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":23},{"fullName":5,"class":6},"Oklahoma State University Center for Health Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Placebo","PLACEBO_COMPARATOR","Brown Rice Powder",[13],"Other: Placebo",{"label":15,"type":16,"description":17,"interventionNames":18},"KSM-66 Ashwagandha","EXPERIMENTAL","600mg daily KSM-66 Ashwagandha",[19],"Dietary Supplement: KSM-66 Ashwagandha",[21,24],{"type":6,"name":9,"description":11,"armGroupLabels":22,"otherNames":23},[9],null,{"type":25,"name":15,"description":17,"armGroupLabels":26,"otherNames":27},"DIETARY_SUPPLEMENT",[15],[28,29,30],"withania somnifera","KSM66","KSM-66",[32,35],{"name":33,"affiliation":5,"role":34},"Julie Croff, PhD","PRINCIPAL_INVESTIGATOR",{"name":36,"affiliation":5,"role":34},"Erica Crockett, MPH",[38],{"name":39,"role":40,"phone":41,"phoneExt":23,"email":42},"Research Scientist","CONTACT","918-517-6151","erica.crockett@okstate.edu",{"type":34,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Erica Crockett","Research Associate","100642063","the-impacts-of-ashwagandha-supplementation-on-diurnal-cortisol-and-stress-among-women-100642063",false,"NCT07647081","The Impacts of Ashwagandha Supplementation on Diurnal Cortisol and Stress Among Women","Female Adversity and Biology: Stress Reduction","FAB:SR","Inclusion Criteria:\n\n1. Female, ages 18-45\n2. No hormonal birth control\n3. Identify as having a regular sleep schedule (eg. sleep by 1am and wake by 9am)\n4. Identify as having a regular menstrual period between 27-32 days apart on average\n5. PSS score of 14 (moderate stress) or greater\n6. No expected changes in stress levels over the next 3 months and agree to not initiate any new stress-reduction behaviors before study start or during the study\n\nExclusion Criteria:\n\n1. Diagnosed major depressive disorder or generalized anxiety disorder in the last 3 months, any liver, kidney, or thyroid disorder\u002Fdysfunction\u002Finjury, or diabetes\n2. Using any medication related to cortisol or HPA function such as corticosteroids, antidepressants, anti-psychotics, CNS-depressants (benzodiazepines, non-benzodiazepine sedatives, barbiturates, anti-convulsants, anesthetics), thyroid medications, diabetic medications, or immunosuppressants\n3. Taken any form of ashwagandha within the last 3 months\n4. Daily use of alcohol, nicotine, or other substances\n5. Who are pregnant, planning to become pregnant, breastfeeding, or have had a hysterectomy\n6. Abnormal liver function test value(s) at screening",true,"FEMALE","18 Years","45 Years",{"count":59,"type":60},30,"ESTIMATED","INTERVENTIONAL",[63],"NA","The purpose of this project is to better understand the role of ashwagandha on the stress response and wellbeing among healthy, stressed women.",[66],"Stress",[68,69,70,71,72],"stress","women","ashwagandha","cortisol","female","NOT_YET_RECRUITING","2026-06-09",{"date":76,"type":77},"2026-06-15","ACTUAL",{"date":79,"type":60},"2026-06",{"date":81,"type":60},"2027-05",{"name":5,"class":6}]