[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100503165":3},{"organization":4,"armGroups":7,"interventions":33,"overallOfficials":11,"centralContacts":43,"locations":51,"responsibleParty":69,"collaborators":11,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":73,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":11,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":11,"overallStatus":54,"whyStopped":11,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"University Hospital, Ghent","OTHER",[8,15,18,22,26,30],{"label":9,"type":10,"description":11,"interventionNames":12},"Supervised training + immediate hormone substitution therapy per SOC","EXPERIMENTAL",null,[13,14],"Other: Exercise program","Drug: Hormonal substitution therapy per SOC",{"label":16,"type":10,"description":11,"interventionNames":17},"Supervised training + delayed hormone substitution therapy per SOC",[13],{"label":19,"type":20,"description":11,"interventionNames":21},"Delayed supervised training + immediate hormone substitution therapy per SOC","ACTIVE_COMPARATOR",[14],{"label":23,"type":10,"description":24,"interventionNames":25},"Supervised training","Subjects who will start hormone substitution therapy in standard of care can participate in the trial and have 50% chance to be randomised in the exercise group.",[13],{"label":27,"type":28,"description":29,"interventionNames":11},"No supervised training","NO_INTERVENTION","Subjects who will start hormone substitution therapy in standard of care can participate in the trial and have 50% chance to be randomised in the non-exercise group.",{"label":31,"type":28,"description":32,"interventionNames":11},"Control group","Subjects with menopausal complaints who do not want hormone substitution therapy or supervised training, can also participate in the trial.",[34,38],{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":11},"Exercise program","The intervention consists of a supervised exercise program",[23,16,9],{"type":39,"name":40,"description":41,"armGroupLabels":42,"otherNames":11},"DRUG","Hormonal substitution therapy per SOC","Subjects take hormonal substitution therapy per standard of care",[19,9],[44,49],{"name":45,"role":46,"phone":47,"phoneExt":11,"email":48},"Herman Depypere","CONTACT","003293323783","studieco.vrouwenkliniek@uzgent.be",{"name":50,"role":46,"phone":47,"phoneExt":11,"email":48},"Study coordinator Women's Clinic",[52],{"facility":53,"status":54,"city":55,"state":11,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Ghent University Hospital - Women's Clinic","RECRUITING","Ghent","9000","Belgium","BE",{"type":60,"coordinates":61},"Point",[62,63],3.71667,51.05,{"lat":63,"lon":62},[66],{"name":11,"role":46,"phone":67,"phoneExt":11,"email":68},"+3293320758","gynobs.studies@uzgent.be",{"type":70,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100503165","the-influence-of-hormone-replacement-therapy-and-supervised-exercise-training-on-body-composition-cardiovascular-risk-and-insulin-sensitivity-in-postmenopausal-women-100503165",false,"NCT05831709","The Influence of Hormone Replacement Therapy and Supervised Exercise Training on Body Composition, Cardiovascular Risk and Insulin Sensitivity in Postmenopausal Women","De Invloed Van Hormoonsubstitutietherapie en Gesuperviseerde Training op Lichaamssamenstelling, Cardiovasculair Risico en Insulinegevoeligheid Bij Postmenopauzale Vrouwen","OPERATE","Inclusion Criteria:\n\n* Postmenopausal women (diagnosed by physician) with complaints due to menopause\n* Indication for hormonal substitution therapy (except for the control group)\n* Good general health\n* BMI: 20-30 kg\u002Fm2\n* Only the use of cholesterol-, blood pressure- or\u002Fand thyroid-regulating medication is permitted","FEMALE","45 Years","65 Years",{"count":83,"type":84},390,"ESTIMATED","INTERVENTIONAL",[87],"NA","This trial investigates whether supervised training in combination with hormonal substitution therapy has an impact on body composition, cardiovascular risk, risk for dementia, osteoporosis and insulin sensitivity in postmenopausal women.",[90,91],"Postmenopause","Menopausal Complaints","2025-11-14",{"date":94,"type":95},"2025-11-18","ACTUAL",{"date":97,"type":95},"2023-05-12",{"date":99,"type":84},"2028-12",{"name":5,"class":6},1]