[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627522":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":40,"centralContacts":44,"locations":49,"responsibleParty":66,"collaborators":31,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":31,"enrollmentInfo":78,"targetDuration":31,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":52,"whyStopped":31,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Pirogov Russian National Research Medical University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1 (1470 nm)","EXPERIMENTAL","Laser crossectomy will be performed with a wavelength of 1470 nm and radial fiber with a core diameter of 0.4 mm and a bulb diameter of 1.57 mm at a power of 6-8 W by manual extraction at a speed of 1 mm\u002Fs (LED of 60-80 J\u002Fcm). EVLT of the great saphenous vein (GSV) trunk will be performed with a standard approach.",[13],"Procedure: Laser crossectomy on 1470 nm",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 2 (1940 nm)","Laser crossectomy will be performed with a wavelength of 1940 nm and radial fiber with a core diameter of 0.55 mm and a bulb diameter of 1.4 mm at a power of 4-6 W by manual extraction at a speed of 1 mm\u002Fs (LED of 40-60 J\u002Fcm). EVLT of the GSV trunk will be performed with a standard approach.",[18],"Procedure: Laser crossectomy on 1940 nm",{"label":20,"type":21,"description":22,"interventionNames":23},"Control","ACTIVE_COMPARATOR","Will contain patients who have failed to perform laser crossectomy at 1470 nm or 1940 nm wavelength due to technical impossibility or technical failure, and underwent EVLT of the GSV trunk with preservation of the stump.",[24],"Procedure: Standard EVLT with a stump",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"PROCEDURE","Laser crossectomy on 1470 nm","Attempt to perform laser crossectomy with radial fiber (core of 0.4 mm, bulb of 1.57 mm) on the 1470 nm wavelength laser with a power of 6-8 W and an LED of 60-80 J\u002Fcm. Performing the GSV trunk ablation according to the indications.",[9],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Laser crossectomy on 1940 nm","Attempt to perform laser crossectomy with radial fiber (core of 0.55 mm, bulb of 1.4 mm) on the 1940 nm wavelength laser with a power of 4-6 W and an LED of 40-60 J\u002Fcm. Performing the GSV trunk ablation according to the indications.",[15],{"type":27,"name":37,"description":38,"armGroupLabels":39,"otherNames":31},"Standard EVLT with a stump","Attempted laser crossectomy on 1470 nm or 1940 nm failed due to anatomical features of the SFJ or technical reasons, and the GSV trunk was obliterated with persistence of the stump.",[20],[41],{"name":42,"affiliation":5,"role":43},"Kirill Lobastov, PhD","PRINCIPAL_INVESTIGATOR",[45],{"name":42,"role":46,"phone":47,"phoneExt":31,"email":48},"CONTACT","+79852116331","lobastov_kv@hotmail.com",[50],{"facility":51,"status":52,"city":53,"state":31,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"MedSwiss Private Cinic","RECRUITING","Moscow","143082","Russia","RU",{"type":58,"coordinates":59},"Point",[60,61],37.61781,55.75204,{"lat":61,"lon":60},[64],{"name":42,"role":46,"phone":65,"phoneExt":31,"email":48},"+7-985-211-63-31",{"type":43,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Kirill Lobastov","Professor of the Department of General surgery named after V.M. Buyanov","100627522","the-influence-of-laser-crossectomy-with-different-wavelengths-on-varicose-vein-progression-100627522",false,"NCT07449728","The Influence of Laser Crossectomy With Different Wavelengths on Varicose Vein Progression","LACROSS-VVP","Inclusion Criteria:\n\n* Age \\>18 years\n* Primary VVs of Clinical Etiology Anatomy Pathophysiology (CEAP) clinical class of C2-C6\n* Reflux along the GSV trunk lasting \\>0.5 sec.\n* GSV trunk diameter ≤12 mm\n* Informed consent to participate in the study\n\nExclusion Criteria:\n\n* Primary reflux outside the GSV trunk (including combined reflux)\n* History of deep or superficial vein thrombosis\n* Deep vein reflux\n* Non-thrombotic or post-thrombotic venous obstruction\n* Pelvic venous insufficiency\n* Use of oral anticoagulants\n* Indication for pharmacological prophylaxis after EVLT\n* Inability to use radial fiber of 1.4-1.57 mm at the surgeon's discretion\n* Refusal to participate in the study","ALL","18 Years",{"count":79,"type":80},400,"ESTIMATED","INTERVENTIONAL",[83],"NA","Technically successful laser crossectomy will reduce the risk of reflux recurrence at the sapheno-femoral junction without increasing the risk of endovenous heat-induced thrombosis, which may positively impact the likelihood of ultrasound- or clinical-recurrence of varicose veins. Similar technical efficacy is expected for laser crossectomy at 1940 nm and 1470 nm. A possible advantage of the 1940 nm wavelength in terms of postoperative pain intensity and the risk of adverse events cannot be ruled out.",[86,87],"Varicose Veins","Chronic Venous Insufficiency",[89,90,91,92,93],"Varicose veins","Endovenous laser treatment","Reflux","Recurrence","Crossectomy","2026-02-26",{"date":96,"type":97},"2026-03-04","ACTUAL",{"date":99,"type":97},"2026-01-20",{"date":101,"type":80},"2029-01-20",{"name":5,"class":6},1]