[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100335224":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":42,"responsibleParty":61,"collaborators":24,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":24,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":24,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":92,"whyStopped":24,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"University Hospital Hradec Kralove","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Desflurane Group","EXPERIMENTAL","Induction and anesthesia will be held by using desflurane",[13],"Procedure: Desflurane Group",{"label":15,"type":10,"description":16,"interventionNames":17},"Propofol Group","Induction and anesthesia will be held by using target-control anesthesia with propofol",[18],"Procedure: Propofol Group",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","General anesthesia will be held using desflurane in end- tidal concentration according to target value of entropy levels (between 40 and 60).",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"General anesthesia will be held using Schnider effect model for propofol (target control anesthesia). Titration will be done according to target value of entropy levels (between 40 and 60).",[15],[29],{"name":30,"affiliation":31,"role":32},"Pavel Dostal, MD, Ph.D.","Hradec Kralove, Czechia 50005","STUDY_DIRECTOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},"Vlasta Dostalova, MD, Ph.D.","CONTACT","+420777883571","vlasta.dostalova@fnhk.cz",{"name":30,"role":36,"phone":40,"phoneExt":24,"email":41},"+420495833218","pavel.dostal@fnhk.cz",[43],{"facility":5,"status":24,"city":44,"state":24,"zip":45,"country":46,"countryCode":24,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Hradec Králové","50005","Czechia",{"type":48,"coordinates":49},"Point",[50,51],15.83277,50.20923,{"lat":51,"lon":50},[54,58],{"name":55,"role":36,"phone":56,"phoneExt":24,"email":57},"Suchy Tomas, MD","00420495833218","suchy@fnhk.cz",{"name":59,"role":36,"phone":60,"phoneExt":24,"email":41},"Dostal Pavel, MD, PhD","00420495832828",{"type":62,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Dostalova Vlasta, MD, PhD","Principal Investigator","100335224","the-influence-of-prone-position-for-spinal-surgery-on-visual-acuity-100335224",false,"NCT03644641","The Influence of Prone Position for Spinal Surgery on Visual Acuity","The Influence of Prone Position for Spinal Surgery on Visual Acuity, a Comparison of Volatile Anesthesia With Desflurane to Total Intravenous Anesthesia With Propofol","Inclusion Criteria:\n\n* Glasgow Coma scale 15\n* American Society of Anesthesiologists (ASA) Physical Status Classification System I-III\n* spinal surgery in duration less than 3 hours\n* sinus rhythm\n\nExclusion Criteria:\n\n* postoperative artificial ventilation\n* serious neurological disease\n* lung disease with hypercapnia\n* propofol allergy","ALL","18 Years","65 Years",{"count":76,"type":77},60,"ESTIMATED","INTERVENTIONAL",[80],"NA","This study investigated the effect of desflurane and propofol anesthesia on visual acuity in patients in prone position for spinal surgery. Many trials have investigated the effects of different anesthetic agents on intraocular pressure, propofol may reduce intraocular pressure more than other intravenous anesthetics.",[83],"Vision; Disorder, Loss",[85,86,87,88,89,90,91],"Desflurane","Near-infrared spectroscopy","Propofol","Spinal surgery","Prone position","Visual acuity","Visual loss","NOT_YET_RECRUITING","2024-05-09",{"date":95,"type":96},"2024-05-10","ACTUAL",{"date":98,"type":77},"2025-11-28",{"date":100,"type":77},"2029-12-30",{"name":5,"class":6},1]