[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100366126":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":27,"locations":33,"responsibleParty":48,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":68,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":10,"interventionNames":11},"Smokers",null,[12,13],"Diagnostic Test: biopsy for oral cancer","Diagnostic Test: periodontal examination",{"label":15,"type":10,"description":10,"interventionNames":16},"non-Smokers",[12,13],[18,23],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"DIAGNOSTIC_TEST","biopsy for oral cancer","surgical biopsy is to be taken for diagnosis of oral cancer or premalignant lesions",[9,15],{"type":19,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"periodontal examination","Periodontal clinical examination to all by periodontal charting",[9,15],[28],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Ayat Gamal-AbdelNaser","CONTACT","01001874257","ayat.gamal@dentistry.cu.edu.eg",[34],{"facility":5,"status":10,"city":35,"state":10,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Cairo","11562","Egypt","EG",{"type":40,"coordinates":41},"Point",[42,43],31.24967,30.06263,{"lat":43,"lon":42},[46],{"name":47,"role":30,"phone":31,"phoneExt":10,"email":32},"Ayat A Gamal-AbdelNaser",{"type":49,"investigatorFullName":29,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Principal investigator","100366126","the-link-between-periodontitis-smoking-and-oral-cancer-100366126",false,"NCT04047212","The Link Between Periodontitis, Smoking and Oral Cancer","Analysis of the Link Between Periodontitis, Smoking and Oral Cancer: Cohort Study","Inclusion Criteria:\n\n* Patients 18 years or older.\n\nExclusion Criteria:\n\n* Patients with any systemic diseases.\n* Pregnant females.\n* Handicapped and mentally retarded patients.\n* Patients undergoing radiotherapy.\n* Patients having oral cancer","ALL","18 Years",{"count":61,"type":62},200,"ESTIMATED","OBSERVATIONAL","Periodontitis is a widely prevalent disease worldwide that has serious public health consequences. Its prognosis includes tooth loss and edentulism, a condition that negatively affects chewing causing functional disability; and esthetics causing social impairment. Consequently, periodontitis may end up causing marked impairment of the quality of life of the affected patients, impairment of general health and increasing the dental care costs significantly.\n\nChanges in the oral mucosa arise by primary products resulting from tissue breakdown due to gingivitis. It then triggers the host cells to produce proteinases that mediate loss of marginal periodontal ligaments, apical migration of the junctional epithelium and apical spread of bacterial biofilm.\n\nTherefore, this research aims to identify the risk of smoking to both periodontitis and oral cancer, and the risk of periodontitis to oral cancer.",[66,67],"Chronic Periodontitis","Oral Cancer","NOT_YET_RECRUITING","2021-06-13",{"date":71,"type":72},"2021-06-16","ACTUAL",{"date":74,"type":62},"2021-08-12",{"date":76,"type":62},"2032-01-30",{"name":5,"class":6},1]