[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100458345":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":12,"centralContacts":16,"locations":25,"responsibleParty":41,"collaborators":7,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":7,"eligibilityCriteria":50,"healthyVolunteers":46,"sex":51,"minAge":52,"maxAge":7,"enrollmentInfo":53,"targetDuration":7,"studyType":56,"phases":7,"briefSummary":57,"conditions":58,"keywords":66,"overallStatus":28,"whyStopped":7,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"The University of Hong Kong","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"COVID-19 outbreaks","The intervention of the study is the COVID-19 outbreaks in Hong Kong. The pre-and post-COVID-19 outbreak periods will be defined as 1 January 2010 - 31 December 2019 and 1 January 2020 - 31 December 2024, respectively.",[13],{"name":14,"affiliation":5,"role":15},"Cindy L.K. Lam, MD","PRINCIPAL_INVESTIGATOR",[17,21],{"name":14,"role":18,"phone":19,"phoneExt":7,"email":20},"CONTACT","+852-25185653","clklam@hku.hk",{"name":22,"role":18,"phone":23,"phoneExt":7,"email":24},"Eric Y.F Wan, PhD","+852-2552-5756","yfwan@hku.hk",[26],{"facility":27,"status":28,"city":29,"state":29,"zip":7,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Department of Family Medicine & Primary Care, LKS Faculty of Medicine, University of Hong Kong","RECRUITING","Hong Kong","China","CN",{"type":33,"coordinates":34},"Point",[35,36],114.17469,22.27832,{"lat":36,"lon":35},[39,40],{"name":14,"role":18,"phone":19,"phoneExt":7,"email":20},{"name":14,"role":15,"phone":7,"phoneExt":7,"email":7},{"type":15,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Professor Cindy L.K. Lam","Clinical Professor, Chairperson of Department of Family Medicine & Primary Care","100458345","the-long-term-spill-over-impact-of-covid-19-on-health-and-healthcare-of-people-with-non-communicable-diseases-100458345",false,"NCT05248412","The Long-term Spill-over Impact of COVID-19 on Health and Healthcare of People With Non-communicable Diseases","The Long-term Spill-over Impact of COVID-19 on Health and Healthcare of Patients With Non-communicable Diseases (and Without COVID-19) : an In-depth Outcome and Health Economic Evaluation","(For cohort study)\n\nInclusion Criteria:\n\n* People aged 18 years or above with a documented doctor-diagnosed NCDs (diabetes mellitus, hypertension, cardiovascular disease, cancer, chronic kidney disease, or chronic respiratory disease )\n* People who attended at least once HA hospitals, general or specialist out-patients clinics between 1 January 2010 and 31 December 2024\n\nExclusion Criteria:\n\n\\- People with a documented doctor-diagnosed COVID-19\n\n(For cross-sectional study)\n\nInclusion Criteria:\n\n* People aged 18 years or above with a documented doctor-diagnosed NCDs (diabetes mellitus, hypertension, cardiovascular disease, cancer, chronic kidney disease, or chronic respiratory disease )\n* All participants are able to communicate in either Chinese or English and provide informed consent.\n\nExclusion Criteria:\n\n* People with a documented diagnosis of COVID-19 during the study period.","ALL","18 Years",{"count":54,"type":55},250000,"ESTIMATED","OBSERVATIONAL","Objectives and aim: To evaluate the long-term spill-over (indirect) effect of Coronavirus disease (COVID-19) on health outcomes and healthcare utilization among people with non-communicable diseases and without COVID-19.\n\nDesign: A population-based cohort study using electronic health records of the Hospital Authority (HA) clinical management system, economic modeling, and serial cross-sectional surveys on healthcare service utilization.\n\nSetting: HA public hospitals and outpatient clinics in Hong Kong\n\nParticipants: People aged ≥ 18 years with a documented diagnosis of diabetes mellitus, hypertension, cardiovascular disease, cancer, chronic respiratory disease, and chronic kidney disease; without COVID-19; attending HA services between 2010 and 2024.\n\nMain outcome measures: All-cause mortality, disease-specific outcomes, healthcare service utilization, and costs.\n\nMethods: The annual incidence of each outcome in each year between 2010 and 2024 will be calculated. An interrupted time-series analysis to assess the changes in outcomes between pre-and-post-COVID-19 outbreak periods. Long term health economic impact of healthcare disruptions during the COVID-19 outbreak will be modeled using microsimulation. Multivariable Cox proportional hazards regression and Poisson\u002Fnegative binomial regression to evaluate the effect of different modes of care on the risk of the outcomes.\n\nImplications: Findings will inform policies and practices on contingency care plans to avoid excessive morbidity and mortality and to assure the quality of care for patients with NCD as part of the territorial response to the health crisis.",[59,60,61,62,63,64,65],"Diabetes Mellitus","Hypertension","Cancer","Cardiovascular Diseases","Chronic Respiratory Disease","Kidney Disease, Chronic","Noncommunicable Diseases",[67,68,69,70,65],"COVID-19 Pandemic","Morality","Complication","Utilization, Health Care","2022-02-20",{"date":73,"type":74},"2022-03-08","ACTUAL",{"date":76,"type":74},"2021-06-21",{"date":78,"type":55},"2026-06-30",{"name":5,"class":6},1]