[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100527194":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":23,"locations":29,"responsibleParty":46,"collaborators":50,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":18,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":18,"overallStatus":32,"whyStopped":18,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Hvidovre University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intermittent carbohydrate restriction","EXPERIMENTAL","Four weeks of intermittent carbohydrate restriction: a dietary regime alternating between two days of restricting carbohydrate intake to 70-90 grams, while energy intake is ad libitum, from fat- and protein-containing foods, and two days of non-restricted diet.",[13],"Other: Dietary macronutrient composition",{"label":15,"type":16,"description":17,"interventionNames":18},"Control arm","NO_INTERVENTION","Four weeks of free-living with no dietary restrictions.",null,[20],{"type":6,"name":21,"description":9,"armGroupLabels":22,"otherNames":18},"Dietary macronutrient composition",[9],[24],{"name":25,"role":26,"phone":27,"phoneExt":18,"email":28},"Amanda Schaufuss, MSc","CONTACT","+4530270261","amanda.schaufuss@regionh.dk",[30],{"facility":31,"status":32,"city":33,"state":18,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Department of Endocrinology, Hvidovre Hospital","RECRUITING","Hvidovre","2650","Denmark","DK",{"type":38,"coordinates":39},"Point",[40,41],12.47708,55.64297,{"lat":41,"lon":40},[44],{"name":45,"role":26,"phone":18,"phoneExt":18,"email":18},"Kirstine Nyvold Bojsen-Møller, MD, PhD",{"type":47,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Kirstine Nyvold Bojsen-Moeller","MD, PhD, Associate Professor",[51,53],{"name":52,"class":6},"University of Copenhagen",{"name":54,"class":6},"Danish Research Centre for Magnetic Resonance","100527194","the-metabolic-impact-of-intermittent-carbohydrate-restriction-in-individuals-with-type-2-diabetes-100527194",false,"NCT06144593","The Metabolic Impact of Intermittent Carbohydrate Restriction in Individuals With Type 2 Diabetes","INTERCARB","Inclusion Criteria:\n\n* Men or women\n* 35-75 years old\n* BMI \\>27 kg\u002Fm2\n* Known type 2 diabetes in stable glucose lowering therapy (for three months) or with HbA1c \\>48 mmol\u002Fmol if no glucose lowering therapy\n\nExclusion Criteria:\n\n* Anemia (hemoglobin \\\u003C8 mmol\u002FL for men and \\\u003C7 mmol\u002FL for women)\n* TSH outside reference range\n* Treatment with insulin, sulfonylurea, or SGLT2-inhibitors\n* Treatment with systemic corticosteroids\n* HbA1c \\>70 mmol\u002Fmol\n* eGFR \\\u003C60 ml\u002Fmin\u002F1.73 m2\n* Contraindications for MR-scan: abdominal height exceed limitations of the MR-scanner, pacemaker or other electronic device implanted, implanted metal devices, severe claustrophobia\n* Food allergies (including lactose and gluten intolerance)\n* Vegetarian\u002Fvegan diet or following of specific dietary plans\n* Alcohol consumptions \\>84\u002F168 g\u002Fweek (women\u002Fmen)\n* Strenuous activity level \\> 120 minutes per week\n* Weight loss (\\>5 kg) within the last three months or previous bariatric surgery\n* High risk of fibrosis of the liver (estimated by FIB4 score \\> 3.25)","ALL","35 Years","75 Years",{"count":66,"type":67},14,"ESTIMATED","INTERVENTIONAL",[70],"NA","The primary aim of this randomized cross-over intervention study is to investigate the effect of four weeks of intermittent carbohydrate restriction (alternating between two days of normal dietary intake and two days of carbohydrate restriction to 70-90 grams) on 24-hour average sensor glucose in individuals with type 2 diabetes compared with a four-week control period with normal dietary intake.",[73,74,75,76],"Diabetes Mellitus, Type 2","Overweight and Obesity","Non-Alcoholic Fatty Liver Disease","Metabolic Syndrome","2024-06-05",{"date":79,"type":80},"2024-06-06","ACTUAL",{"date":82,"type":80},"2024-01-03",{"date":84,"type":67},"2025-09-01",{"name":5,"class":6},1]