[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100390586":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":36,"centralContacts":40,"locations":46,"responsibleParty":61,"collaborators":22,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":22,"eligibilityCriteria":69,"healthyVolunteers":66,"sex":70,"minAge":71,"maxAge":22,"enrollmentInfo":72,"targetDuration":22,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":22,"overallStatus":49,"whyStopped":22,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Subjects at risk for NAFLD","Adult Olmsted County residents identified as at risk for NAFLD will receive Magnetic Resonance Imaging (MRE,) blood tests,and possible biopsy.",[12,13,14,15],"Diagnostic Test: Magnetic Resonance Elastography","Other: Blood draw","Procedure: Liver biopsy","Procedure: Fibro Scan",[17,23,27,32],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"DIAGNOSTIC_TEST","Magnetic Resonance Elastography","Combines MRI imaging with sound waves to create a visual map (elastogram) showing the stiffness of body tissues.",[9],null,{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":22},"Blood draw","Clinical blood tests with a focus on liver function parameters and diabetes",[9],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":22},"PROCEDURE","Liver biopsy","If indicated per MRE results a biopsy will be taken of the liver.",[9],{"type":28,"name":33,"description":34,"armGroupLabels":35,"otherNames":22},"Fibro Scan","If indicated per MRE results a fibroscan will be performed of the liver.",[9],[37],{"name":38,"affiliation":5,"role":39},"ALINA M ALLEN, MD","PRINCIPAL_INVESTIGATOR",[41],{"name":42,"role":43,"phone":44,"phoneExt":22,"email":45},"Jodie A Cogswell","CONTACT","507-266-3995","cogswell.jodie@mayo.edu",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":22},"Mayo Clinic in Rochester","RECRUITING","Rochester","Minnesota","55905","United States","US",{"type":56,"coordinates":57},"Point",[58,59],-92.4699,44.02163,{"lat":59,"lon":58},{"type":39,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":22,"oldOrganization":22},"Alina M. Allen","Principal Investigator","100390586","the-olmsted-nafld-epidemiology-study-tones-100390586",false,"NCT04365855","The Olmsted NAFLD Epidemiology Study (TONES)","Inclusion Criteria:\n\n* Olmsted County residents at the time of search\n* Age 18 or older\n* No personal history of NAFLD diagnosis (administrative codes)\n\nExclusion Criteria:\n\n* Alcohol in excess (more than 20 gm per week in women and 30 gm per week in men)\n* Currently pregnant\n* Have contraindications to MRI (MRI incompatible implanted devices, severe claustrophobia)","ALL","18 Years",{"count":73,"type":74},800,"ESTIMATED","INTERVENTIONAL",[77],"NA","Researchers are assessing the prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) in the population and assembling a well-characterized cohort of adults with NAFLD and NASH to validate models of NAFLD diagnosis and determine long-term outcomes.",[80,81],"Non-Alcoholic Fatty Liver Disease","Non-Alcoholic Steatohepatitis","2026-01-14",{"date":84,"type":85},"2026-01-16","ACTUAL",{"date":87,"type":85},"2020-10-10",{"date":89,"type":74},"2028-06",{"name":5,"class":6},1]