[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624489":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":26,"locations":34,"responsibleParty":47,"collaborators":19,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":19,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":19,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":75,"whyStopped":19,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Lancaster University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Bodyweight push-up and squat variations","EXPERIMENTAL","The participant will select a variation of the push-up and squat. This will either be beginner, intermediate or advanced. Muscle activity in the triceps and quadriceps muscle groups will be measured for the push-up and squat patterns respectively.",[13],"Other: Resistance Exercise Protocol",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Resistance Exercise Protocol","The intervention involves performing progressive variations of squat and push-up patterns to technical failure while monitored by EMG electrodes on the triceps and quadriceps. Participants verbally signal a \"moderate\" discomfort threshold (5\u002F10) during each set to identify the repetition gap between perceived strain and actual physical exhaustion. This structured exercise task serves to calibrate subjective effort against objective muscle activation (%MVC) to map the physiological mechanics of fatigue.",[9],null,[21,24],{"name":22,"affiliation":5,"role":23},"Paul Hendrickse, PhD","PRINCIPAL_INVESTIGATOR",{"name":25,"affiliation":5,"role":23},"Lawrence Hayes, PhD",[27,32],{"name":28,"role":29,"phone":30,"phoneExt":19,"email":31},"Matthew Davitt, Msc","CONTACT","07743061291","m.davitt@lancaster.ac.uk",{"name":22,"role":29,"phone":30,"phoneExt":19,"email":33},"p.hendrickse@lancaster.ac.uk",[35],{"facility":5,"status":19,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":19},"Lancaster","Lancashire","LA1 4YW","United Kingdom","UK",{"type":42,"coordinates":43},"Point",[44,45],-2.79988,54.04649,{"lat":45,"lon":44},{"type":23,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Matthew Davitt","PhD Student","100624489","the-perceived-point-of-muscular-discomfort-vs-the-point-of-failure-in-the-ageing-population--a-pilot-study-100624489",false,"NCT07410299","The Perceived Point of Muscular Discomfort vs the Point of Failure in the Ageing Population- a Pilot Study","The Perceived Point of Moderate Muscular Discomfort vs the Point of Technical Failure in the Ageing Population- a Pilot Study.","Inclusion Criteria:\n\n* Aged 60-80 years of age.\n* Physically capable of resistance training.\n* Able to walk unassisted.\n\nExclusion Criteria:\n\n* Major cardiovascular (e.g. myocardial infarction, angioplasty within the last year, coronary artery bypass graft), neurological (e.g. Parkinson's disease, Alzheimer's, major anxiety or depressive disorders), muscular (e.g., muscular dystrophies, myopathies, myositis) or uncontrolled metabolic conditions (e.g. Type 1 or 2 diabetes).\n* Severe obesity (BMI \\>39).\n* Have undertaken regular resistance exercise in the last 12 months.\n* Any upper or lower body musculoskeletal injury that impairs the participants ability to perform a repetition as fast as possible.\n* Acute or terminal illnesses (e.g. severe locals or systemic infections, cancer).\n* Current residence being within a setting of care.\n* Experience of muscle pain from taking statins.",true,"ALL","60 Years","80 Years",{"count":62,"type":63},15,"ESTIMATED","INTERVENTIONAL",[66],"NA","This is an investigation into the differences in muscle activation and numerical difference in reps between the feeling of moderate discomfort and technical failure during a set of bodyweight resistance exercise.\n\nThe investigators know that resistance training is an essential tool for older people to maintain muscle function, valuable independence and autonomy in daily tasks. The idea of completing a set of resistance training activity to the point of failing a repetition due to fatigue regularly has been shown to not be appealing and could be a reason why there are low participation rates among older people for in weight training regularly.\n\nResearch has also shown that it is not necessary to train to failure (being unable to continue to complete repetitions of an exercise with the proper technique due to fatigue), but the investigators would like to know if training to a point of moderate discomfort can also allow for the muscles to gain the positive changes associated with weight training, potentially making it more accessible and enjoyable.\n\nUsing bodyweight exercises (a squat pattern and a push up pattern) the investigators will see how many repetitions after the point of perceived moderate discomfort is stated at which the point of failure is. the investigators will also measure muscle activation in the quadriceps and triceps with EMG (a device that can detect the muscles' electrical activity\u002F how hard it is working) to see at which point the muscle is working the hardest.",[69],"Muscle Fatigue Caused by Repetitive Muscle Exercise",[71,72,73,74],"fatigue","Ageing population","resistance exercise","electromyography","NOT_YET_RECRUITING","2026-02-07",{"date":78,"type":79},"2026-02-13","ACTUAL",{"date":81,"type":63},"2026-02-10",{"date":83,"type":63},"2026-03-10",{"name":5,"class":6},1]