[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623004":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":7,"responsibleParty":21,"collaborators":7,"id":23,"slug":24,"hasResults":25,"nctId":26,"briefTitle":27,"officialTitle":28,"acronym":29,"eligibilityCriteria":30,"healthyVolunteers":25,"sex":31,"minAge":32,"maxAge":7,"enrollmentInfo":33,"targetDuration":7,"studyType":36,"phases":7,"briefSummary":37,"conditions":38,"keywords":40,"overallStatus":45,"whyStopped":7,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":7},{"fullName":5,"class":6},"Fondazione Ricerca e Innovazione Cardiovascolare ETS","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Filippo Luca Gurgoglione","A.O.U. di Parma","PRINCIPAL_INVESTIGATOR",[14,19],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"Filippo Gurguglione","CONTACT","+393312048150","mailto:filippolucagurgoglione@gmail.com",{"name":20,"role":16,"phone":7,"phoneExt":7,"email":7},"Beatrice Barbano",{"type":22,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100623004","the-piccoleto-ix-pheno-study-100623004",false,"NCT07390994","The PICCOLETO IX PHENO Study","Prognostic Impact of PHENOtyping de Novo Coronary Artery Disease Prior to Drug-Coated Balloon Angioplasty by Optical Coherence Tomography (PICCOLETO IX PHENO)","PIX-PHENO","Inclusion Criteria:\n\n* Chronic coronary syndrome or acute coronary syndrome diagnosis (per ESC guidelines).\n* De novo obstructive CAD: ≥50% left main stenosis, or any stenosis ≥70%, or FFR \\\u003C0.80 in any other major epicardial vessel, or MLA deemed ischemic at intravascular imaging.\n* OCT assessment of the target segment phenotype prior to lesion preparation and DCB angioplasty.\n* Successful DCB angioplasty according to DCB ARC criteria.\n* Patients who underwent DCB-only PCI, or hybrid DCB-DES PCI with at least 20 mm of the target segment treated with DCB.\n\nExclusion Criteria:\n\n* Previous revascularization of the target segment with stent.\n* Hybrid DCB-DES PCI with DCB-treated segment \\\u003C20 mm and\u002For lacking complete OCT assessment of the DCB-treated segment and\u002For bailout stenting.\n* Lack of at least 6 months of clinical follow up.\n* PCI of chronic total occlusion.","ALL","18 Years",{"count":34,"type":35},600,"ESTIMATED","OBSERVATIONAL","To investigate whether pre-procedural OCT-derived de novo coronary lesion phenotype (lipid-rich, fibrotic, calcific; and ACS mechanisms such as plaque rupture\u002Ferosion\u002Fcalcified nodule) is associated with clinical outcomes after DCB angioplasty.",[39],"Coronary Artery Disease",[41,42,43,44],"Drug-Coated Balloon","Optical Coherence Tomography","Percutaneous Coronary Intervention","Plaque phenotype","NOT_YET_RECRUITING","2026-01-29",{"date":48,"type":49},"2026-02-05","ACTUAL",{"date":51,"type":35},"2026-01-09",{"date":53,"type":35},"2027-04-20",{"name":5,"class":6}]