[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631652":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":39,"responsibleParty":63,"collaborators":18,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":18,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":18,"enrollmentInfo":74,"targetDuration":18,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":85,"overallStatus":42,"whyStopped":18,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Central Denmark Region","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"POCT-supported assessment","EXPERIMENTAL","Ambulance clusters in the intervention arm use prehospital point-of-care testing (POCT) integrated with telemedical consultation. For clinically stable patients in whom conveyance is uncertain, ambulance clinicians may perform on-scene biochemical testing (electrolytes, renal function, C-reactive protein, hemoglobin, leukocyte count) following approval from an Emergency Medical Dispatch Centre (EMDC) physician. Test results support clinical decision-making regarding hospital conveyance in addition to standard EMS assessment.",[13],"Diagnostic Test: Point-of-care testing (POCT)",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard care","NO_INTERVENTION","Ambulance clusters in the control arm provide standard prehospital assessment and care according to regional EMS guidelines. Decisions regarding hospital conveyance or non-conveyance are based on clinical evaluation and telemedical consultation as needed, without access to point-of-care blood testing.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DIAGNOSTIC_TEST","Point-of-care testing (POCT)","On-scene biochemical testing performed using portable point-of-care devices. non-conveyance.",[9],[26],{"name":27,"affiliation":28,"role":29},"Martin F Gude, MD, PhD","Prehospital Emergency Medical Services, Central Denmark Region. Denmark","PRINCIPAL_INVESTIGATOR",[31,35],{"name":27,"role":32,"phone":33,"phoneExt":18,"email":34},"CONTACT","004525343621","martgude@rm.dk",{"name":36,"role":32,"phone":37,"phoneExt":18,"email":38},"Ulla Væggemose, PhD","004578414912","ulla.vaeggemose@ph.rm.dk",[40],{"facility":41,"status":42,"city":43,"state":18,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Prehospital Emergency Medical Services, Central Denmark Region, Denmark","RECRUITING","Aarhus N","8200","Denmark","DK",{"type":48,"coordinates":49},"Point",[50,51],10.17317,56.20367,{"lat":51,"lon":50},[54,58,62],{"name":55,"role":32,"phone":56,"phoneExt":18,"email":57},"Mille S Jensen, BSc","004551164460","misjns@rm.dk",{"name":59,"role":32,"phone":60,"phoneExt":18,"email":61},"Nicoline B Jensen, BSc","004523261931","nibuje@rm.dk",{"name":27,"role":29,"phone":18,"phoneExt":18,"email":18},{"type":64,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100631652","the-pre-poct-non-conveyance-trial-prehospital-point-of-care-testing-to-support-non-conveyance-decisions-100631652",false,"NCT07503470","The Pre-POCT-Non-Conveyance Trial: Prehospital Point-of-Care Testing to Support Non-Conveyance Decisions","Prehospital Point-of-Care Testing to Support Decision-Making in Alternative and Non-Conveyance Pathways: A Matched Parallel Cluster-Randomised Trial. The Pre-POCT-Non-Conveyance Trial","Inclusion Criteria:\n\n* Adults aged ≥18 years\n* Emergency call or general practitioner-commissioned ambulance dispatch following telephone triage only, including video streaming triage, resulting in ambulance dispatch\n* Initial on-scene assessments performed by the ambulance crew\n* Patients initially considered for hospital conveyance based on clinical assessment\n* Following telemedical consultation with an Emergency Medical Dispatch Centre (EMDC) physician, deemed eligible for point-of-care blood testing (POCT)\n* Hemodynamically and clinically stable according to predefined operational stability criteria (including Glasgow Coma Scale, blood pressure, oxygen saturation, and heart rate), with final eligibility determined by the EMDC physician based on overall clinical assessment and the patient's baseline status\n\nExclusion Criteria:\n\n* Non-emergency calls (e.g., interfacility transport or scheduled patient transport)\n* General practitioner-commissioned ambulance dispatches where the patient has been physically assessed by a general practitioner or another physician before ambulance arrival\n* Immediate need for emergency transport to hospital as determined by clinical assessment\n* Persistent unstable vital signs outside predefined operational thresholds, except for known chronic baseline deviations (e.g., reduced oxygen saturation in patients with chronic obstructive pulmonary disease or chronic tachyarrhythmia in atrial fibrillation)\n* Inability to obtain venous or capillary blood samples\n* Prior participation in the study within 30 days (to ensure complete outcome follow-up)","ALL","18 Years",{"count":75,"type":76},1500,"ESTIMATED","INTERVENTIONAL",[79],"NA","The goal of this clinical trial is to evaluate whether rapid blood tests performed in the ambulance can be implemented in routine prehospital assessment of adults who are initially considered for transport to hospital. Ambulance clinicians frequently assess adults who are transported to hospital but discharged shortly after arrival without requiring advanced diagnostic testing or treatment.\n\nIn this study, researchers will examine whether adding rapid point-of-care blood testing (POCT) at the scene supports ambulance clinicians and Emergency Medical Dispatch Centre (EMDC) physicians in making more informed decisions about hospital conveyance. POCT provides rapid measurements of biomarkers including infection markers, electrolytes, kidney function, blood counts, and total carbon dioxide, a proxy measure related to acid-base status.\n\nTen ambulance clusters will participate in a matched, cluster-randomized design. Half will provide standard care, and half will have access to POCT following consultation with an EMDC physician in patients who would otherwise be considered for hospital transport.\n\nThe main question is whether prehospital POCT can be performed, documented, and made available before the final conveyance decision in routine ambulance-based assessment. The study will also examine whether access to POCT is associated with a higher proportion of patients remaining at home rather than being transported to hospital.\n\nSafety outcomes will include hospital admission within 24 hours among non-conveyed patients, short-stay hospitalization, intensive care unit (ICU) admission, and 30-day mortality.\n\nThis study will evaluate the implementation of POCT-supported decision-making in prehospital care and explore whether it may increase non-conveyance without compromising patient safety.",[82,83,84],"Prehospital Emergency Medical Services","Prehospital Emergency Care","Point of Care Testing",[86,87,88,89,90],"emergency medical services","point of care testing","POCT","Non-conveyance","decision-making","2026-05-29",{"date":93,"type":94},"2026-06-01","ACTUAL",{"date":96,"type":94},"2026-05-26",{"date":98,"type":76},"2027-12-31",{"name":5,"class":6},1]