[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100551471":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":30,"responsibleParty":106,"collaborators":10,"id":108,"slug":109,"hasResults":110,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":114,"eligibilityCriteria":115,"healthyVolunteers":110,"sex":116,"minAge":117,"maxAge":118,"enrollmentInfo":119,"targetDuration":10,"studyType":122,"phases":10,"briefSummary":123,"conditions":124,"keywords":126,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":140},{"fullName":5,"class":6},"Hospices Civils de Lyon","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Intensive care unit patient with shock, who don't be in perioperative of cardiac surgery",null,"Patients of age superior or equal of 18 years, with a vasopressor support superior 0.5 µg\u002Fkg\u002Fmin of equivalent norepinephrine during more than 30 minutes.\n\nThe patients are not in perioperative of cardiac surgery (between the beginning of the intervention and 7 days after).\n\nThe patients have a monitoring of arterial pressure with a radial arterial catheter, and the physician decided to have a monitoring of arterial pressure with a femoral arterial catheter.",[13],"Other: Non-invasive blood pressure measurements",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Non-invasive blood pressure measurements","Non-invasive blood pressure measurements to the tension cuff three times in a row on each side (right arm and left arm)",[9],[20,26],{"name":21,"role":22,"phone":23,"phoneExt":24,"email":25},"Matthias Jacquet-lagreze, Dr","CONTACT","0783426888","+33","matthias.jacquet-lagreze@chu-lyon.fr",{"name":27,"role":22,"phone":28,"phoneExt":24,"email":29},"Martin Ruste, Dr","0472118956","martin.ruste@chu-lyon.fr",[31,47,61,71,82,95],{"facility":32,"status":33,"city":34,"state":10,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Département d'anesthésie Réanimation Hôpital Cardiologique Louis Pradel\u002FGroupement Hospitalier Est","RECRUITING","Bron","69500","France","FR",{"type":39,"coordinates":40},"Point",[41,42],4.91303,45.73865,{"lat":42,"lon":41},[45],{"name":46,"role":22,"phone":23,"phoneExt":24,"email":25},"Matthias Jacquet-Lagreze, Dr",{"facility":48,"status":33,"city":49,"state":10,"zip":50,"country":36,"countryCode":37,"cosmosGeoPoint":51,"geoPoint":55,"contacts":56},"Hopital Edouard heriot\u002FGroupement hospitalier Centre, service de médecine intensive réanimation","Lyon","69003",{"type":39,"coordinates":52},[53,54],4.84789,45.74906,{"lat":54,"lon":53},[57],{"name":58,"role":22,"phone":59,"phoneExt":24,"email":60},"Neven Stevic, Dr","0472112838","neven.stevic@chu-lyon.fr",{"facility":62,"status":33,"city":49,"state":10,"zip":50,"country":36,"countryCode":37,"cosmosGeoPoint":63,"geoPoint":65,"contacts":66},"Hôpital Edouard Heriot\u002F Groupement hospitalier Centre, service d'anesthésie réanimation",{"type":39,"coordinates":64},[53,54],{"lat":54,"lon":53},[67],{"name":68,"role":22,"phone":69,"phoneExt":24,"email":70},"Stanislas Abrard, Dr","0472112310","Stanislas.abrard@chu-lyon.fr",{"facility":72,"status":33,"city":49,"state":10,"zip":73,"country":36,"countryCode":37,"cosmosGeoPoint":74,"geoPoint":76,"contacts":77},"Hôpital de la Croix-Rousse\u002FGroupement hospitalier Nord, service d'anesthésie réanimation","69004",{"type":39,"coordinates":75},[53,54],{"lat":54,"lon":53},[78],{"name":79,"role":22,"phone":80,"phoneExt":24,"email":81},"Marie-Charlotte Delignette, Dr","0472309070","Marie-charlotte.delignette@chu-lyon.fr",{"facility":83,"status":33,"city":49,"state":10,"zip":84,"country":36,"countryCode":37,"cosmosGeoPoint":85,"geoPoint":87,"contacts":88},"Hôpital Saint Joseph Saint Luc","69007",{"type":39,"coordinates":86},[53,54],{"lat":54,"lon":53},[89,93],{"name":90,"role":22,"phone":91,"phoneExt":24,"email":92},"Emmanuel Vivier, Dr","04 78 61 83 98","evivier@saintjosephsaintluc.fr",{"name":90,"role":94,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"facility":96,"status":33,"city":49,"state":10,"zip":97,"country":36,"countryCode":37,"cosmosGeoPoint":98,"geoPoint":100,"contacts":101},"Centre hospitalier Lyon Sud\u002FGroupement hospitalier Sud, Service d'anesthésie réanimation médecine intensive","69495",{"type":39,"coordinates":99},[53,54],{"lat":54,"lon":53},[102],{"name":103,"role":22,"phone":104,"phoneExt":24,"email":105},"Auguste Dargent, Dr","04 78 86 20 06","Auguste.dargent@chu-lyon.fr",{"type":107,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100551471","the-prevalence-of-the-aortic-to-radial-pressure-gradient-in-states-of-shock-outside-the-context-of-cardiac-surgery-a-prospective-study-100551471",false,"NCT06460519","The Prevalence of the Aortic to Radial Pressure Gradient in States of Shock, Outside the Context of Cardiac Surgery, a Prospective Study","Prevalence of the Aortic to Radial Pressure Gradient in States of Shock","PARECHOC","Inclusion Criteria:\n\n* age superior or equal 18 years\n* Vasopressors support superior or equal 0.5 µg\u002Fkg\u002Fmin of equivalent norepinephrine\n* Invasive monitoring of blood pressure with a radial arterial catheter and a femoral arterial catheter decided by de physician\n* Beginning of the shock less than 48 hours.\n* Consent\n\nExclusion Criteria:\n\n* perioperative of cardiac surgery (between the beginning of the surgery and 7 days after)\n* pregnant woman or breast-feeding\n* Major person under protection\n* Person with privation of liberty by a justice decision, or an administrative decision","ALL","18 Years","99 Years",{"count":120,"type":121},180,"ESTIMATED","OBSERVATIONAL","First described in cardiac surgery, the aortic to radial pressure gradient (ATRAP) is the cause of an underestimation of the aortic pressure with a measure assumed with a radial catheter, and he can concert 1 of 3rd patients. The risks factor well known are small height, previous hypertension, long and difficult surgery, radial artery diameter less than 1.8mm.\n\nThe ATRAP definition is a pressure difference between radial and femoral (same of the aortic pressure) pressure of 25mmHg on the systolic pressure, or a pressure difference on the mean pressure of 10mmHg, both measures realised by arterial canulation, and with a duration superior than 5 minutes.\n\nIf this gradient appears in pathophysiological specifics situations, there is a risk of inappropriate administration of vasopressors, with more hospitalisation days, more side effect of vasopressors like an augmentation of myocardial work.\n\nThe ATRAP is documented in septic shock with a prevalence between 21% and 27%. The ATRAP can appear in shocks, moreover with doses of equivalent norepinephrine of 0.5 µg\u002Fkg\u002Fmin who is use for the definition of refractive shock, the difference between the two pressure is higher if the dose of equivalent norepinephrine is higher than 1µg\u002Fkg\u002Fmin. But the prevalence and risks factors are barely unknowns in this situation.\n\nMost of the time, a radial arterial catheter is used for hemodynamic monitoring for his simplicity of utilisation and the lows complications associated. Some medical teams in cardiac surgeries, or in intensive care unit (ICU) for the management of shocks used often radial and femoral arterial catheter. It seems there is no at risk for the utilisation of a radial and femoral arterial canulation.\n\nOut of the situation of cardiac surgery, there is a lack of information of the ATRAP, the objective of the study is to evaluate the prevalence of the ATRAP in shock, out of the situation of cardiac surgery.",[125],"Shock",[127,128,129,130],"Radial artery","Femoral artery","Norepinephrine equivalent","Intensive care unit","2026-04-14",{"date":133,"type":134},"2026-04-17","ACTUAL",{"date":136,"type":134},"2024-10-03",{"date":138,"type":121},"2027-11-03",{"name":5,"class":6},6]