[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100502116":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":32,"centralContacts":44,"locations":55,"responsibleParty":71,"collaborators":32,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":32,"eligibilityCriteria":79,"healthyVolunteers":75,"sex":80,"minAge":81,"maxAge":32,"enrollmentInfo":82,"targetDuration":32,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":92,"overallStatus":57,"whyStopped":32,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"E-DA Hospital","OTHER",[8,15,21],{"label":9,"type":10,"description":11,"interventionNames":12},"One biopsy","EXPERIMENTAL","Obtain one biopsy specimen at the proximal part of the the longest columnar-lined esophagus for patients with suspected Barrett's Esophagus",[13,14],"Procedure: One biopsy","Device: Endoscopy",{"label":16,"type":17,"description":18,"interventionNames":19},"Three biopsy","ACTIVE_COMPARATOR","Obtain three biopsy specimens at the proximal, middle and distal part of the longest columnar-lined esophagus for patients with suspected Barrett's Esophagus",[20,14],"Procedure: Three biopsy",{"label":22,"type":23,"description":24,"interventionNames":25},"Seattle protocol","SHAM_COMPARATOR","Obtain 4-quadrant biopsy specimens at intervals of every 1 to 2 cm throughout the the columnar-lined esophagus for patients with suspected Barrett's Esophagus",[26,14],"Procedure: Seattle protocol",[28,33,36,39],{"type":29,"name":9,"description":30,"armGroupLabels":31,"otherNames":32},"PROCEDURE","To do one biopsy at the proximal part of the longest columnar-lined esophagus.",[9],null,{"type":29,"name":16,"description":34,"armGroupLabels":35,"otherNames":32},"To do three biopsy at the proximal, middle and distal part of the longest columnar-lined esophagus.",[16],{"type":29,"name":22,"description":37,"armGroupLabels":38,"otherNames":32},"To do 4-quadrant biopsy every 1-2 cm at the esophagogastric junction. Seattle protocol has been considered as the gold standard biopsy protocol for patients with suspected Barrett's Esophagus.",[22],{"type":40,"name":41,"description":42,"armGroupLabels":43,"otherNames":32},"DEVICE","Endoscopy","The participants will receive meticulous endoscopic examination with narrow-band imaging.",[9,22,16],[45,51],{"name":46,"role":47,"phone":48,"phoneExt":49,"email":50},"Ying-Nan Tsai, M.D","CONTACT","886-7-6150011","252294","littlepig9933@gmail.com",{"name":52,"role":47,"phone":48,"phoneExt":53,"email":54},"Wen-Lun Wang, Ph.D","251346","warrengodr@gmail.com",[56],{"facility":5,"status":57,"city":58,"state":32,"zip":59,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"RECRUITING","Kaohsiung City","82445","Taiwan","TW",{"type":63,"coordinates":64},"Point",[65,66],120.31333,22.61626,{"lat":66,"lon":65},[69],{"name":70,"role":47,"phone":48,"phoneExt":49,"email":50},"Ying Nan Tsai, M.D",{"type":72,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR","100502116","the-prevalence-risk-factors-and-optimal-biopsy-protocol-of-be-100502116",false,"NCT05818072","The Prevalence, Risk Factors and Optimal Biopsy Protocol of BE","The Prevalence, Risk Factors and Optimal Biopsy Protocol of Barrett's Esophagus in Taiwan - A Prospective Randomized Study","Inclusion Criteria:\n\n* Adults with columnar-lined esophagus\n\nExclusion Criteria:\n\n* A prior history of endoscopic treatment for Barrett's Esophagus\n* A prior history of upper gastrointestinal malignancy\n* A prior history of total or subtotal gastrectomy\n* Esophageal varices noted during the procedure\n* Uncontrolled coagulopathy\n* Taking antiplatelet drug or anticoagulant","ALL","20 Years",{"count":83,"type":84},165,"ESTIMATED","INTERVENTIONAL",[87],"NA","Detections of goblet cells and dysplasia are crucial for diagnosis and determining the surveillance program of Barrett's esophagus (BE). However, the optimal biopsy numbers and their yield rates of intestinal metaplasia (IM) and dysplasia are still uncertain, especially in Asia. The aim of this study was to determine the optimal biopsy protocol of BE.",[90,91],"Barrett's Esophagus","Intestinal Metaplasia",[90,93,94],"Columnar-lined esophagus","Intestinal metaplasia","2023-05-09",{"date":97,"type":98},"2023-05-11","ACTUAL",{"date":100,"type":98},"2023-03-13",{"date":102,"type":84},"2026-12-31",{"name":5,"class":6},1]