[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629712":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":40,"locations":24,"responsibleParty":46,"collaborators":49,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":24,"enrollmentInfo":62,"targetDuration":24,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":74,"whyStopped":24,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":24},{"fullName":5,"class":6},"Stanford University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PROACT Platform - Minimally Facilitated Testing","EXPERIMENTAL","The Minimally Facilitated testing arm is a simplified version of the PROACT-AI platform, that provides participants with access to low-cost testing only, in addition to standard of care.",[13],"Other: Minimally facilitated platform",{"label":15,"type":10,"description":16,"interventionNames":17},"PROACT Platform - AI","The AI-powered arm will provide participants access to low-cost testing via an AI-powered platform as well as provide additional features including genetic education, motivational interviewing, family communication, and complete follow-up surveys.",[18],"Other: AI-powered platform",[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Minimally facilitated platform","This group will receive access to low-cost genetic testing via an email link and an access code.",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"AI-powered platform","This group will receive access to low-cost genetic testing via an AI-powered platform that will also provide genetic education, motivational interviewing, and family communication",[15],[30,33,35,38],{"name":31,"affiliation":5,"role":32},"Allison Kurian, MD","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":5,"role":32},"Jennifer Lee Caswell-Jin, MD",{"name":36,"affiliation":37,"role":32},"Steven Katz, MD","University of Michigan",{"name":39,"affiliation":37,"role":32},"Lawrence An, MD",[41],{"name":42,"role":43,"phone":44,"phoneExt":24,"email":45},"Sonia Rios-Ventura","CONTACT","6507258762","proactprogram@stanford.edu",{"type":32,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Jennifer Lee Caswell-Jin","Assistant Professor of Medicine (Oncology)",[50],{"name":37,"class":6},"100629712","the-preventive-risk-outreach-and-cascade-testing-100629712",false,"NCT07478237","The Preventive Risk Outreach And Cascade Testing","The Preventive Risk Outreach and Cascade Testing (PROACT)","PROACT","Inclusion Criteria - Probands\n\n1. Age ≥ 18 years old.\n2. Known to carry a pathogenic or likely pathogenic variant in a gene included in the 2024 current Color Health Cancer Panel Test.\n3. Have at least one (1) first- or second-degree relative who is living in the United States and has not yet had germline genetic testing.\n\nExclusion Criteria - Probands\n\n1\\. Unable to read and write English or Spanish.\n\nInclusion Criteria - Relatives\n\n1. Age ≥ 18 years old.\n2. Resides in the United States.\n\nExclusion Criteria - Relatives\n\n1. Completed genetic testing by a clinician within the last 5 years that included the pathogenic or likely pathogenic variant.\n2. Not a first- or second-degree relative of the proband.",true,"ALL","18 Years",{"count":63,"type":64},400,"ESTIMATED","INTERVENTIONAL",[67],"NA","The goal of this clinical trial is to learn whether a new online program developed by the research team is able to help families learn about family cancer risk and how to reduce this risk, as well as help interested family members get low-cost, at-home genetic testing for cancer risk.",[70,71],"Genetic Predisposition","Family Members",[73],"Cascade genetic testing","NOT_YET_RECRUITING","2026-05-11",{"date":77,"type":78},"2026-05-14","ACTUAL",{"date":80,"type":64},"2026-06",{"date":82,"type":64},"2029-12",{"name":5,"class":6}]