[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560919":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":24,"centralContacts":28,"locations":38,"responsibleParty":69,"collaborators":10,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":74,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":85,"studyType":86,"phases":10,"briefSummary":87,"conditions":88,"keywords":92,"overallStatus":40,"whyStopped":10,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Women with > 3 months amenorrhea",null,"Women aged 18-40 years old with a diagnosis of functional hypothalamic amenorrhea, or lab results that are within the inclusion criteria.",[13,14],"Other: Automated Self-Administered 24-hour Dietary Assessment Tool (ASA24)","Other: REVEAL Questionnaire",[16,20],{"type":6,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"Automated Self-Administered 24-hour Dietary Assessment Tool (ASA24)","Subjects will complete the ASA food diary for 2 weekdays and 1 weekend day",[9],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"REVEAL Questionnaire","Subjects will complete the REVEAL questionnaire form. This form includes questions about current and past medical history, including reproductive history, lifestyle specifics, and assessment of current health status.",[9],[25],{"name":26,"affiliation":5,"role":27},"Chrisandra Shufelt, MD","PRINCIPAL_INVESTIGATOR",[29,34],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"Chandler E. Palmer, MHA","CONTACT","904-953-5438","palmer.chandler@mayo.edu",{"name":35,"role":31,"phone":36,"phoneExt":10,"email":37},"Chrisandra L Shufelt, MD","904 953-7224","DLREVEAL@exchange.mayo.edu",[39,58],{"facility":5,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Jacksonville","Florida","32224","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-81.65565,30.33218,{"lat":50,"lon":49},[53,54,57],{"name":26,"role":31,"phone":10,"phoneExt":10,"email":37},{"name":55,"role":56,"phone":10,"phoneExt":10,"email":10},"Stephanie Faubion, MD","SUB_INVESTIGATOR",{"name":26,"role":27,"phone":10,"phoneExt":10,"email":10},{"facility":5,"status":40,"city":59,"state":60,"zip":61,"country":44,"countryCode":45,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"Rochester","Minnesota","55905",{"type":47,"coordinates":63},[64,65],-92.4699,44.02163,{"lat":65,"lon":64},[68],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},{"type":27,"investigatorFullName":70,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Chrisandra L. Shufelt, MD","Chair and Professor of Medicine","100560919","the-registry-of-very-early-estrogen-and-anovulation-100560919",false,"NCT06583408","The REgistry of Very Early Estrogen and AnovuLation","REVEAL","Inclusion Criteria:\n\n* 3 or more months of consecutive amenorrhea with a diagnosis of functional hypothalamic amenorrhea or screening hormones consistent with functional hypothalamic amenorrhea including but not limited to:\n\n  * Estradiol: \\\u003C 50pg\u002FmL\n  * LH: \\\u003C 10 IU\u002FmL\n  * FSH: \\\u003C 10 IU\n  * Testosterone: 2 - 45 ng\u002FdL\n  * Free Testosterone: 0.1 - 6.4 pg\u002FmL\n  * FT4: 0.93 - 1.70 ng\u002FdL\n  * Prolactin: \\\u003C 20 ng\u002FmL\n  * AMH: \\> 1 ng\u002FmL\n  * Urine or serum human chorionic gonadotropin: Negative\n* LH:FSH Ratio \\\u003C1\n* No signs of male-like hair growth on the upper lip, chin, chest, abdomen, buttocks, or back\n* Does not have a diagnosis for secondary amenorrhea, including prolactinoma, PCOS, premature ovarian insufficiency, pituitary surgery, infection, or infarction\n* Premenopausal status determined by WISE criteria\n* Able to give informed consent\n* Able to read English\n\nExclusion Criteria:\n\n* Parturition\u002Flactating in the last 6-12 months\n* Lack of consent","FEMALE","18 Years","40 Years",{"count":83,"type":84},100000,"ESTIMATED","5 Years","OBSERVATIONAL","The purpose of this study is to to build a registry of women with early estrogen loss due to Functional Hypothalamic Amenorrhea (FHA) to understand the prevalence, racial and ethnic diversity of this condition.",[89,90,91],"Hypothalamic Amenorrhea, Functional","Hypothalamic Amenorrhea","Functional Hypogonadotropic Hypogonadism",[93,94,95],"Anovulation","Estrogen Loss","Hypoestrogenemia","2025-11-18",{"date":98,"type":99},"2025-11-21","ACTUAL",{"date":101,"type":99},"2024-07-01",{"date":103,"type":84},"2029-08-01",{"name":5,"class":6},2]