[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100510830":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":27,"centralContacts":32,"locations":41,"responsibleParty":61,"collaborators":10,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":65,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":10,"studyType":77,"phases":10,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University College Cork","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Low fibre consumers",null,"Healthy adults consuming less than or equal to 18 grams of fibre per day.",[13],"Other: Dietary fibre",{"label":15,"type":10,"description":16,"interventionNames":17},"Moderate fibre consumers","Healthy adults consuming between 18.1-24.9 grams of fibre per day.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"High fibre consumers","Healthy adults consuming greater than or equal to 25 grams of fibre per day.",[13],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Dietary fibre","Habitual dietary consumption from a variety of foods will be assessed using 7-day food logs entered by the participant and assessed for accuracy by a dietitian.",[19,9,15],[28],{"name":29,"affiliation":30,"role":31},"John F Cryan, PhD","APC Microbiome Irealnd","PRINCIPAL_INVESTIGATOR",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Elizabeth Schneider, PhD","CONTACT","(+353) 021 4901721","eschneider@ucc.ie",{"name":39,"role":35,"phone":36,"phoneExt":10,"email":40},"Revathy Munuswamy, PhD","RMunuswamy@ucc.ie",[42],{"facility":43,"status":44,"city":45,"state":10,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"APC Microbiome Ireland","RECRUITING","Cork","T12YT20","Ireland","IE",{"type":50,"coordinates":51},"Point",[52,53],-8.47061,51.89797,{"lat":53,"lon":52},[56,57,58],{"name":39,"role":35,"phone":36,"phoneExt":10,"email":40},{"name":29,"role":31,"phone":10,"phoneExt":10,"email":10},{"name":59,"role":60,"phone":10,"phoneExt":10,"email":10},"Gerard Clarke, PhD","SUB_INVESTIGATOR",{"type":62,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100510830","the-relationship-between-diet-cognition-stress-and-the-gut-microbiota-100510830",false,"NCT05931536","The Relationship Between Diet, Cognition, Stress, and the Gut Microbiota","The Relationship Between Diet, Cognition, Stress, and the Gut Microbiota: A Cross-sectional Study in Healthy Adults","NMB","Inclusion Criteria:\n\n* Be able to give written informed consent.\n* Be between 18 and 50 years of age.\n* Have a body mass index (BMI) between 18.5-29.9 Kg\u002Fm2.\n* Be in generally good health as determined by the investigator.\n\nExclusion Criteria:\n\n* Are less than 18 and greater than 50 years of age.\n* Have a BMI below 18.5 or above 29.9 Kg\u002Fm2.\n* Have a significant acute or chronic coexisting illness \\[cardiovascular, gastrointestinal (GI) \\[to include functional GI disorders, inflammatory bowel disease, coeliac disease, lactose intolerance, food allergies\\], immunological, psychiatric \\[to include formal or as determined by MINI Psychiatric interview, diagnosis of current major depression, anxiety disorder, bipolar spectrum disorder, schizophrenia, other DSM-IV Axis I disorder\\], neurodevelopmental disorders, immunological, metabolic disorders \\[to include type I or II diabetes\\], or any condition which contraindicates, in the investigators judgement, entry to the study.\n* Have a condition or taking a medication that the investigator believes would interfere with the objectives of the study, pose a safety risk, or confound the interpretation of the study results; all psychoactive medications \\[to include anxiolytics, antipsychotics, antidepressants, anticonvulsants, centrally acting corticosteroids, and opioid pain relievers), laxatives, enemas, antibiotics, anti-coagulants, over-the counter non-steroidal anti-inflammatories (NSAIDS). Subjects should have a wash-out period of 4 weeks.\n* Current prebiotic or probiotic supplement use (a wash-out period of 4 weeks after cessation will allow entry to the study).\n* Females who are peri-menopausal, menopausal or post-menopausal.\n* Females who are pregnant or planning a pregnancy, or lactating.\n* Participants who are not fluent in English.\n* Are colour blind.\n* Have dyslexia or dyscalculia.\n* Are a current habitual daily smoker.\n* Individuals who, in the opinion of the investigator, are considered to be poor attendees or unlikely for any reason to be able to comply with the trial.\n* Subjects receiving treatment involving experimental drugs. If the subject has been in a recent experimental trial, these must have been completed not less than 30 days prior to this study.\n* Have a malignant disease or any concomitant end-stage organ disease.\n* Have completed a study in our laboratory in the past 4 years.","ALL","18 Years","50 Years",{"count":75,"type":76},350,"ESTIMATED","OBSERVATIONAL","This study aims to investigate the relationship between diet and the microbiota-gut-brain axis.",[80],"Healthy",[82,83,84,85,24],"Microbiota-gut-brain axis","Diet","Cognition","Stress","2024-09-20",{"date":88,"type":89},"2024-09-24","ACTUAL",{"date":91,"type":89},"2022-07-14",{"date":93,"type":76},"2025-07-14",{"name":5,"class":6},1]