[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100581369":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":15,"collaborators":10,"id":19,"slug":20,"hasResults":21,"nctId":22,"briefTitle":23,"officialTitle":24,"acronym":10,"eligibilityCriteria":25,"healthyVolunteers":21,"sex":26,"minAge":27,"maxAge":10,"enrollmentInfo":28,"targetDuration":10,"studyType":31,"phases":10,"briefSummary":32,"conditions":33,"keywords":10,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"1-First group will include the control group (22) 2- Second group will include PD patients",null,"22 people will be included in the control group who don't have PD and 22 patients with PD will be enrolled from the clinic of movement disorders of neuropsychiatry hospital of Assiut University and divided into early PD less than 3 years and late more than 3 years",{"label":13,"type":10,"description":14,"interventionNames":10},"1-First group will include the control group (22)","2-Second will include PD patients (22) whose will be collected from the clinic of movement disorders of Neuropsychiatry hospital of Assiut University and then divided into :a-early PD less than 3 years b-late PD more than 3 years",{"type":16,"investigatorFullName":17,"investigatorTitle":18,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Shrouk Mohammed Hossam Eldien Abdelmohsen","principle investigator","100581369","the-relationship-between-homocysteine-and-manifestation-of-parkinsons-disease-patients-100581369",false,"NCT06849414","The Relationship Between Homocysteine and Manifestation of Parkinson's Disease Patients","The Relationship Between Blood Homocysteine Level and Motor and Cognitive Manifestation of Parkinson's Disease Patients","Inclusion Criteria:\n\n* 1-Inpatients or outpatients from the clinic of movement disorders of neuropsychiatry hospital of Assiut university 2-The age group of the patients is those above 40 years\n\nExclusion Criteria:\n\n* 1-Secondary parkinsonism associated with specific causes such as infections, medication-induced, poisoning, cerebral arteriosclerosis, and trauma 2-Parkinsonism accompanied by other neurodegenerative disease ( specifically multiple syste atrophy, progressive supranuclear palsy, and dementia with Lewy bodies).\n\n  3-Presence of significant memory or cognitive decline preceding the onset of PD symptoms, as reported by both the patient and\u002For family members 4-Significant intracranial lesions detected on brain MRI 5-Unable to cooperate in completing the clinical scale assessment and blood sample collection.\n\n  6-Recent or current use of medications such as antiepileptic drugs and certain chemotherapy drugs that can impact blood Hcy levels or the presence of thyroid dysfunction or renal insufficiency that affects Hcy metabolism.","ALL","40 Years",{"count":29,"type":30},44,"ESTIMATED","OBSERVATIONAL","* The aim of the current study is to investigate the association between blood homocysteine level and motor as well as cognitive manifestation of PD patients in Assiut governorate.\n* Secondary goal is to investigate the association between levels of serum ferritin, iron as well as acute phase proteins (fibrinogen, D-dimer, CRP) and manifestation of PD.",[34],"Parkinson's Disease","NOT_YET_RECRUITING","2025-02-24",{"date":38,"type":39},"2025-02-27","ACTUAL",{"date":41,"type":30},"2025-06",{"date":43,"type":30},"2026-07",{"name":5,"class":6}]