[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580397":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":10,"centralContacts":26,"locations":32,"responsibleParty":50,"collaborators":10,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":10,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":76,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Neijiang No.2 People's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"The expression of FosB positive group",null,"Researcher will incorporate the positive expression of FosB protein in laryngeal cancer tissues into the positive study group by immunohistochemical methods!",[13],"Other: the expression positive in laryngeal cancer tissue",{"label":15,"type":10,"description":16,"interventionNames":17},"The expression of FosB negative group","Researcher will incorporate the positive expression of FOSB protein in laryngeal cancer tissues into the positive study group and vice versa into the negative study group by immunohistochemical methods!",[18],"Other: the expression negative in laryngeal cancer tissue",[20,23],{"type":6,"name":21,"description":16,"armGroupLabels":22,"otherNames":10},"the expression negative in laryngeal cancer tissue",[15],{"type":6,"name":24,"description":16,"armGroupLabels":25,"otherNames":10},"the expression positive in laryngeal cancer tissue",[9],[27],{"name":28,"role":29,"phone":30,"phoneExt":10,"email":31},"Yang Ji","CONTACT","+86 18283201832","450638020@qq.com",[33],{"facility":34,"status":10,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Cllinical Laboratory of Chuanbei Medical College","Nanchong","China\u002FSiChuan","637000","China","CN",{"type":41,"coordinates":42},"Point",[43,44],106.08473,30.79508,{"lat":44,"lon":43},[47],{"name":48,"role":29,"phone":49,"phoneExt":10,"email":31},"Yang Ji, master","0086+18283201832",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Yang ji","associate professor","100580397","the-relationship-between-the-differential-expression-of-fosb-protein-in-laryngeal-cancer-tissues-and-clinical-prognosis-100580397",false,"NCT06836765","The Relationship Between The Differential Expression Of FosB Protein In Laryngeal Cancer Tissues And Clinical Prognosis","Expression Of FosB Gene In Laryngeal Cancer Tissues And It's Clinical Prognosis Significance","Inclusion Criteria:\n\n* laryngeal squamous cell carcinoma was diagnosed ,and biopsy was confirmed by two pathologists;\n* Primary tumor of Laryngeal ,and there was no distant metastasis;\n* Standard treatment such as surgery and Preliminarily-diagnosed parients;\n* full clinical and pathological data information and good follow-up;\n* there was no previous fatal diseases such as complicated tumors.\n\nExclusion Criteria:\n\n* Secondary cancer or cancer with distant metastasis;\n* Patients who have not seen a doctor for the first time or have received surgery or radiotherapy or chemotherapy in other hospitals;\n* Clinical and pathological data were missing and loss to follow-up;\n* Patients who abandoned treatment or standard treatment procedures has not been completed;\n* The past medical history of other lethal diseases such as complicated tumors.","ALL","35 Years","90 Years",{"count":65,"type":66},100,"ESTIMATED","OBSERVATIONAL","To determine whether there is statisstical difference in FosB (FBJ murine osteosarcoma viral oncogene homolog B) protein expression between laryngeal cancer tissue and adjacent tissue through immunohistochemistry methods.\n\nIf there are differences, further the investigators will collect relevant patients information,such as clinical stages, pathological types, clinical prognosis and so on. ultimately analyze whether it is related to the expression of FOsB in laryngeal cancer tissue and adjacent tissues",[70],"Laryngeal Carcinoma",[72,73,74,75],"Laryngeal cancer","FosB(FBJ murine osteosarcoma viral oncogene homolog B) gene","Immunohistochemistry","Cox regression analysis","NOT_YET_RECRUITING","2025-02-14",{"date":79,"type":80},"2025-02-20","ACTUAL",{"date":82,"type":66},"2025-04-01",{"date":84,"type":66},"2025-05-01",{"name":52,"class":6},1]